Can AI agents conduct open-ended AI research? Early evidence from two case studies
Not on the map. Why?
Abstract (arXiv)
Forecasts of explosive AI progress hinge on AI agents automating AI research. But evidence on whether agents can carry out open-ended AI research is thin. Current evaluations either test agents on narrow, verifiable tasks, which excludes open-ended research, or submit AI-generated papers to blind peer review, which is overstretched, stochastic, and suffers from poor review quality. We introduce a third way to measure progress towards AI R&D automation. An agent takes on the central, open-ended research question of a high-quality unpublished paper, and the paper's original authors grade its output. We call these shadow evaluations. We ran shadow evaluations on two unpublished NeurIPS 2026 submissions, giving frontier agents six days and thousands of dollars of compute. The agents completed all of the engineering without human help, yet could not make substantial progress towards answering the research questions. As a result, both papers were unambiguously rejected by the authors. We identify five recurring failure modes: poor judgment about the bar for publishable research, uncreative responses to shortcomings in the research design, ineffective backtracking from dead ends, poor resource awareness, and instruction drift. A robustness check with a second model and scaffold reproduced these failures. We release the expert reviews, survey responses, agent repositories, and logs. Our results provide early evidence that today's agents can do the engineering of AI research, but struggle with critical parts of the research lifecycle.
Key facts. Cited by 7 papers in the map (data through 7 Oct 2026). Builds on 30 of its 47 references that are in the map. First posted on arXiv 29 Jul 2026.
Builds on
30 of 47 references.
References · 30
- 2024The AI Scientist: Towards Fully Automated Open-Ended Scientific Discoverycited by 1,002
- 2025AlphaEvolve: A coding agent for scientific and algorithmic discoverycited by 763
- 2024MLE-bench: Evaluating Machine Learning Agents on Machine Learning Engineeringcited by 429
- 2025Agent Laboratory: Using LLM Agents as Research Assistantscited by 405
- 2025The AI Scientist-v2: Workshop-Level Automated Scientific Discovery via Agentic Tree Searchcited by 375
- 2024Automated Design of Agentic Systemscited by 360
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- 2025PaperBench: Evaluating AI's Ability to Replicate AI Researchcited by 286
- 2024RE-Bench: Evaluating frontier AI R&D capabilities of language model agents against human expertscited by 153
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- 2024CORE-Bench: Fostering the Credibility of Published Research Through a Computational Reproducibility Agent Benchmarkcited by 115
18 more
- 2025MLGym: A New Framework and Benchmark for Advancing AI Research Agentscited by 111
- 2025AI-Researcher: Autonomous Scientific Innovationcited by 88
- 2025MLR-Bench: Evaluating AI Agents on Open-Ended Machine Learning Researchcited by 57
- 2025CodeScientist: End-to-End Semi-Automated Scientific Discovery with Code-based Experimentationcited by 54
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- 2025EXP-Bench: Can AI Conduct AI Research Experiments?cited by 36
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- 2025MLRC-Bench: Can Language Agents Solve Machine Learning Research Challenges?cited by 27
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Built on by
Citing papers per year: 2026: 7.
7 papers.
- 2026Training AI Scientists to Replicate Researchcited by 4
- 2026How Do Agents Fail on AutoResearch: End-to-End Diagnostic Evaluation on 100 Real-World Frontier Research Taskscited by 4
- 2026Aspire: Can Models Self-Evolve from Vague Goals?cited by 2
- 2026The Emerging AI Paper-Review Arms Race: Adversarial Co-Evolution in Scholarly Publishingcited by 1
- 2026The Evolutionary Origin of Values: implications for AI alignment, sentience and existential riskcited by 0
- 2026A Pathway to General-Purpose Scientific AI: Multimodal Comprehension of Scientific Imagescited by 0
- 2026Agents Are Systems, Not Models: Rethinking Agentic Evaluationcited by 0
- 2026Agents Are Systems, Not Models: Rethinking Agentic Evaluation1 Oct 2026
- 2026The Emerging AI Paper-Review Arms Race: Adversarial Co-Evolution in Scholarly Publishing7 Sep 2026
- 2026Aspire: Can Models Self-Evolve from Vague Goals?31 Aug 2026
- 2026How Do Agents Fail on AutoResearch: End-to-End Diagnostic Evaluation on 100 Real-World Frontier Research Tasks14 Aug 2026
- 2026A Pathway to General-Purpose Scientific AI: Multimodal Comprehension of Scientific Images14 Aug 2026
- 2026Training AI Scientists to Replicate Research13 Aug 2026
- 2026The Evolutionary Origin of Values: implications for AI alignment, sentience and existential risk4 Aug 2026