A Unified Benchmark for Dynamic Medical Treatment Reinforcement Learning
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Abstract (arXiv)
Medical treatment recommendation poses several challenges to reinforcement learning (RL): patient physiology evolves in continuous time, measurements and interventions are performed at irregular intervals, and treatment effects vary substantially across individuals. Existing RL formulations and simulated environments, however, are based on discrete-time MDPs with fixed decision intervals. Thus, it remains difficult to evaluate whether RL methods can handle time-interval-dependent disease progression, personalized treatment response, and safety between consecutive measurement points. To address this gap, we introduce MedGym, a benchmark environment for dynamic treatment recommendation. MedGym models longitudinal patient evolution in a continuous-time framework and constructs a configurable medical RL benchmark from clinical data by using Physics-Informed Neural Networks. The resulting benchmark enables direct comparison between discrete-time and continuous-time methods under irregular treatment timing and patient-specific dynamics. Furthermore, MedGym supports evaluation from clinically important perspectives, such as personalization and trajectory-level safety. By providing a standardized and configurable benchmark for continuous-time dynamic treatment, MedGym enables more realistic and informative evaluation of medical RL methods.
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References · 21
- 2017Proximal Policy Optimization Algorithmscited by 14,441
- 2018Soft Actor-Critic: Off-Policy Maximum Entropy Deep Reinforcement Learning with a Stochastic Actorcited by 4,635
- 2013Playing Atari with Deep Reinforcement Learningcited by 3,211
- 2015Trust Region Policy Optimizationcited by 2,503
- 2020Offline Reinforcement Learning: Tutorial, Review, and Perspectives on Open Problemscited by 1,873
- 2020Conservative Q-Learning for Offline Reinforcement Learningcited by 1,777
- 2019Reinforcement Learning in Healthcare: A Surveycited by 308
- 2016Data-Efficient Off-Policy Policy Evaluation for Reinforcement Learningcited by 285
- 2022A Survey on Offline Reinforcement Learning: Taxonomy, Review, and Open Problemscited by 228
- 2019Empirical Study of Off-Policy Policy Evaluation for Reinforcement Learningcited by 121
- 2022A Review of Off-Policy Evaluation in Reinforcement Learningcited by 92
- 2017Continuous State-Space Models for Optimal Sepsis Treatment - a Deep Reinforcement Learning Approachcited by 68
9 more
- 2018Evaluating Reinforcement Learning Algorithms in Observational Health Settingscited by 60
- 2025MedAgentGym: A Scalable Agentic Training Environment for Code-Centric Reasoning in Biomedical Data Sciencecited by 22
- 2024When to Sense and Control? A Time-adaptive Approach for Continuous-Time RLcited by 9
- 2024DTR-Bench: An in silico Environment and Benchmark Platform for Reinforcement Learning Based Dynamic Treatment Regimecited by 8
- 2024ICU-Sepsis: A Benchmark MDP Built from Real Medical Datacited by 6
- 2021Synthetic Acute Hypotension and Sepsis Datasets Based on MIMIC-III and Published as Part of the Health Gym Projectcited by 5
- 2025Offline Guarded Safe Reinforcement Learning for Medical Treatment Optimization Strategiescited by 4
- 2025Guardian-regularized Safe Offline Reinforcement Learning for Smart Weaning of Mechanical Circulatory Devicescited by 2
- 2020Lagrangian Duality in Reinforcement Learningcited by 1
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