Once-For-All: A Train-Once and Select-Anytime Framework for Multimodal Instruction Tuning

Multimodal instruction tuning is widely used to adapt multimodal large language models (MLLMs), yet the large-scale image-text datasets it relies on are often highly redundant. Existing data selection methods are commonly tied to specific datasets, target models, or training states, requiring retraining or recomputation when transferred to new settings. We ask whether a selection signal can instead be learned once and reused across datasets and models. We propose OnceSelect, a reusable data selector trained once and directly applied to unseen datasets. OnceSelect encodes image-instruction pairs in a frozen joint multimodal space, clusters them into pseudo-labels capturing coarse semantic structure, and trains a lightweight selector using a fixed validation macro-accuracy criterion. Low-confidence samples under the learned partition are treated as informative candidates. As the selector is independent of the downstream MLLM, it can be transferred across datasets without retraining or model-dependent scoring, while selected subsets can be reused across model architectures. Using only 15% of LLaVA-625K, OnceSelect retains 99.2% of full-data aggregate performance across nine evaluation metrics. Without retraining, it achieves 103.4% and 102.5% relative performance on unseen Vision-Flan-186K and LRV-Sub-180K. The same 93.7K LLaVA subset further achieves 99.9-106.7% relative performance across Qwen3-VL and InternVL3 models without model-specific scoring or reselection. These results demonstrate efficient and reusable multimodal data selection across datasets and model architectures. Code is available at https://github.com/DMK041218/OnceSelect