Toward Autonomous Long-Horizon Engineering for ML Research
On the map: LLM agents and tool use → Web, search, and research agents
Abstract (arXiv)
Agentic systems increasingly automate pieces of AI research. Yet turning underspecified research objectives into runnable, experimentally validated ML systems remains a central bottleneck. We study this operational setting as long-horizon ML research engineering: converting a research specification into a runnable ML system through repeated implementation, experimentation, and refinement. The central challenge is to sustain cumulative project progress across heterogeneous stages under delayed, confounded feedback. We introduce AiScientist, a multi-agent system built around thin control over thick state: a lightweight hierarchical research team coordinates through a File-as-Bus workspace that preserves decision-relevant artifacts across roles and invocations. On PaperBench, AiScientist improves over the strongest matched baselines by 9.92 and 11.15 points with Gemini-3-Flash and GLM-5, respectively. On MLE-Bench Lite, it reaches 81.82 Any Medal% under both backbones, improving over the strongest matched baselines by 4.55 and 16.67 points, and exceeding a Codex/GPT-5.5 xhigh frontier harness reference by 13.64 Any Medal points. Ablations and process analyses show that durable project state is central to later-round refinement: removing File-as-Bus lowers PaperBench score by 6.41 points and MLE-Bench Lite Any Medal% by 31.82 points. These results suggest that long-horizon AI research is not only a problem of stronger local reasoning, but a systems problem of maintaining cumulative, inspectable project progress.
Key facts. Cited by 16 papers in the map (data through 13 Oct 2026). Placed in Web, search, and research agents, one of 16 directions in LLM agents and tool use. Builds on 34 of its 41 references that are in the map. First posted on arXiv 14 Apr 2026.
Builds on
34 of 41 references.
Closest ancestors · 9
Same direction, newest first
- 2026MARS: Modular Agent with Reflective Search for Automated AI Research2 Feb
- 2025AI Research Agents for Machine Learning: Search, Exploration, and Generalization in MLE-bench3 Jul
- 2025MLE-STAR: Machine Learning Engineering Agent via Search and Targeted Refinement27 May
- 2025AI-Researcher: Autonomous Scientific Innovation24 May
- 2025PiFlow: Principle-Aware Scientific Discovery with Multi-Agent Collaboration21 May
- 2025R&D-Agent: An LLM-Agent Framework Towards Autonomous Data Science20 May
- 2025The AI Scientist-v2: Workshop-Level Automated Scientific Discovery via Agentic Tree Search10 Apr
- 2025Agent Laboratory: Using LLM Agents as Research Assistants8 Jan
- 2024MLE-bench: Evaluating Machine Learning Agents on Machine Learning Engineering9 Oct
Other references · 25
- 2023MetaGPT: Meta Programming for A Multi-Agent Collaborative Frameworkcited by 1,777
- 2023CAMEL: Communicative Agents for "Mind" Exploration of Large Language Model Societycited by 1,365
- 2024The AI Scientist: Towards Fully Automated Open-Ended Scientific Discoverycited by 1,041
- 2025Why Do Multi-Agent LLM Systems Fail?cited by 573
- 2026GLM-5: from Vibe Coding to Agentic Engineeringcited by 542
- 2025PaperBench: Evaluating AI's Ability to Replicate AI Researchcited by 303
- 2025AIDE: AI-Driven Exploration in the Space of Codecited by 213
- 2025AgentRxiv: Towards Collaborative Autonomous Researchcited by 70
- 2025Paper2Code: Automating Code Generation from Scientific Papers in Machine Learningcited by 68
- 2025DeepScientist: Advancing Frontier-Pushing Scientific Findings Progressivelycited by 61
- 2025Beyond Self-Talk: A Communication-Centric Survey of LLM-Based Multi-Agent Systemscited by 59
- 2025ML-Master: Towards AI-for-AI via Integration of Exploration and Reasoningcited by 59
13 more
- 2025CodeScientist: End-to-End Semi-Automated Scientific Discovery with Code-based Experimentationcited by 55
- 2025Table-Critic: A Multi-Agent Framework for Collaborative Criticism and Refinement in Table Reasoningcited by 32
- 2026Toward Ultra-Long-Horizon Agentic Science: Cognitive Accumulation for Machine Learning Engineeringcited by 27
- 2025LoongFlow: Directed Evolutionary Search via a Cognitive Plan-Execute-Summarize Paradigmcited by 22
- 2025The FM Agentcited by 21
- 2026BeyondSWE: Can Current Code Agent Survive Beyond Single-Repo Bug Fixing?cited by 21
- 2026Immersion in the GitHub Universe: Scaling Coding Agents to Masterycited by 20
- 2025DeepCode: Open Agentic Codingcited by 15
- 2026daVinci-Env: Open SWE Environment Synthesis at Scalecited by 13
- 2026KAPSO: A Knowledge-grounded framework for Autonomous Program Synthesis and Optimizationcited by 11
- 2025Reflective Paper-to-Code Reproduction Enabled by Fine-Grained Verificationcited by 10
- 2025C-3PO: Compact Plug-and-Play Proxy Optimization to Achieve Human-like Retrieval-Augmented Generationcited by 9
- 2026Idea2Story: An Automated Pipeline for Transforming Research Concepts into Complete Scientific Narrativescited by 8
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Citing papers per year: 2026: 16.
16 papers.
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- 2026Toward Generalist Autonomous Research via Hypothesis-Tree Refinementcited by 15
- 2026AutoResearchBench: Benchmarking AI Agents on Complex Scientific Literature Discoverycited by 10
- 2026Frontis-MA1: Training an AI4AI Model towards Recursive Self-Improvement in Machine Learning Engineeringcited by 8
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- 2026Engineering Reliable Coding Agents: Evaluating and Operating the System Around the Model14 Aug 2026
- 2026CalibForge: Adversarial Solver Calibration for Scaling Learnable Terminal Tasks6 Aug 2026
- 2026Frontis-MA1: Training an AI4AI Model towards Recursive Self-Improvement in Machine Learning Engineering30 Jul 2026
- 2026Making AI Scientists Auditable from Evidence to Claim17 Jun 2026
4 more
- 2026MDForge: Agentic Molecular Dynamics Pipeline Design under Sparse Simulator Feedback11 Jun 2026
- 2026Toward Generalist Autonomous Research via Hypothesis-Tree Refinement10 Jun 2026
- 2026GEAR: Genetic AutoResearch for Agentic Code Evolution8 May 2026
- 2026AutoResearchBench: Benchmarking AI Agents on Complex Scientific Literature Discovery28 Apr 2026
- 2026AutoResearchBench: Benchmarking AI Agents on Complex Scientific Literature Discoverycited by 10
- 2026GEAR: Genetic AutoResearch for Agentic Code Evolutioncited by 4
- 2026ScienceFlow: A long-horizon agent for ML research, scientific discovery and beyondcited by 3
- 2026MDForge: Agentic Molecular Dynamics Pipeline Design under Sparse Simulator Feedbackcited by 2
- 2026Engineering Reliable Coding Agents: Evaluating and Operating the System Around the Modelcited by 2
- 2026Advancing Model Research in AgentX: Long-Horizon Autonomy for Industrial Recommender Systemscited by 0
- 2026How Much of a Harness Does a Strong Agent Need for Autonomous ML Engineering?cited by 0
- 2026How Much of a Harness Does a Strong Agent Need for Autonomous ML Engineering?30 Sep 2026
- 2026Advancing Model Research in AgentX: Long-Horizon Autonomy for Industrial Recommender Systems24 Sep 2026
- 2026ScienceFlow: A long-horizon agent for ML research, scientific discovery and beyond14 Aug 2026
- 2026Engineering Reliable Coding Agents: Evaluating and Operating the System Around the Model14 Aug 2026
- 2026MDForge: Agentic Molecular Dynamics Pipeline Design under Sparse Simulator Feedback11 Jun 2026
- 2026GEAR: Genetic AutoResearch for Agentic Code Evolution8 May 2026
- 2026AutoResearchBench: Benchmarking AI Agents on Complex Scientific Literature Discovery28 Apr 2026
- 2026Toward Generalist Autonomous Research via Hypothesis-Tree Refinementcited by 15
- 2026CalibForge: Adversarial Solver Calibration for Scaling Learnable Terminal Taskscited by 5
- 2026Repo-To-Skill: Distilling GitHub Repositories Into AI4AI Skillscited by 2
- 2026Making AI Scientists Auditable from Evidence to Claimcited by 1
- 2026ReproAgent: Contract-Guided Paper-to-Code Reproductioncited by 1
- 2026Strategy Accumulation and Guided Execution for Automated LLM Fine-Tuningcited by 0
- 2026PEAR: Progressive Evidence-Based AutoResearch for Industrial Search Systemscited by 0
- 2026PEAR: Progressive Evidence-Based AutoResearch for Industrial Search Systems28 Sep 2026
- 2026Strategy Accumulation and Guided Execution for Automated LLM Fine-Tuning6 Sep 2026
- 2026Repo-To-Skill: Distilling GitHub Repositories Into AI4AI Skills2 Sep 2026
- 2026ReproAgent: Contract-Guided Paper-to-Code Reproduction25 Aug 2026
- 2026CalibForge: Adversarial Solver Calibration for Scaling Learnable Terminal Tasks6 Aug 2026
- 2026Making AI Scientists Auditable from Evidence to Claim17 Jun 2026
- 2026Toward Generalist Autonomous Research via Hypothesis-Tree Refinement10 Jun 2026
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