mlsanityData to 7 Oct 2026

XrayClaw: Cooperative-Competitive Multi-Agent Alignment for Trustworthy Chest X-ray Diagnosis

arXiv 2604.02695 ↗First posted 3 Apr 2026cs.CVcited by 5

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Abstract (arXiv)

Chest X-ray (CXR) interpretation is a fundamental yet complex clinical task that increasingly relies on artificial intelligence for automation. However, traditional monolithic models often lack the nuanced reasoning required for trustworthy diagnosis, frequently leading to logical inconsistencies and diagnostic hallucinations. While multi-agent systems offer a potential solution by simulating collaborative consultations, existing frameworks remain susceptible to consensus-based errors when instantiated by a single underlying model. This paper introduces XrayClaw, a novel framework that operationalizes multi-agent alignment through a sophisticated cooperative-competitive architecture. XrayClaw integrates four specialized cooperative agents to simulate a systematic clinical workflow, alongside a competitive agent that serves as an independent auditor. To reconcile these distinct diagnostic pathways, we propose Competitive Preference Optimization, a learning objective that penalizes illogical reasoning by enforcing mutual verification between analytical and holistic interpretations. Extensive empirical evaluations on the MS-CXR-T, MIMIC-CXR, and CheXbench benchmarks demonstrate that XrayClaw achieves state-of-the-art performance in diagnostic accuracy, clinical reasoning fidelity, and zero-shot domain generalization. Our results indicate that XrayClaw effectively mitigates cumulative hallucinations and enhances the overall reliability of automated CXR diagnosis, establishing a new paradigm for trustworthy medical imaging analysis.

Key facts. Cited by 5 papers in the map (data through 7 Oct 2026). Builds on 34 of its 46 references that are in the map. First posted on arXiv 3 Apr 2026.

Builds on

34 of 46 references.

References · 34

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22 more
  1. 2025MedRAX: Medical Reasoning Agent for Chest X-raycited by 68
  2. 2025MAM: Modular Multi-Agent Framework for Multi-Modal Medical Diagnosis via Role-Specialized Collaborationcited by 39
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  4. 2024CXPMRG-Bench: Pre-training and Benchmarking for X-ray Medical Report Generation on CheXpert Plus Datasetcited by 33
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Cited by year (2026 to 7 Oct)

Citing papers per year: 2026: 5.

5 papers.

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  1. 2025CXRAgent: Director-Orchestrated Multi-Stage Reasoning for Chest X-Ray Interpretation
  2. 2025RadAgents: Multimodal Agentic Reasoning for Chest X-ray Interpretation with Radiologist-like Workflows
  3. 2026Which Tool Response Should I Trust? Tool-Expertise-Aware Chest X-ray Agent with Multimodal Agentic Learning
  4. 2025AT-CXR: Uncertainty-Aware Agentic Triage for Chest X-rays
  5. 2026CXReasonAgent: Evidence-Grounded Diagnostic Reasoning Agent for Chest X-rays
  6. 2026DUCX: Decomposing Unfairness in Tool-Using Chest X-ray Agents
  7. 2026Reliability Stress Tests and Decision-Time Routing for Chest X-ray Vision-Language Models
  8. 2025PASS: Probabilistic Agentic Supernet Sampling for Interpretable and Adaptive Chest X-Ray Reasoning