mlsanityData to 7 Oct 2026

AI Agents Can Already Autonomously Perform Experimental High Energy Physics

arXiv 2603.20179 ↗First posted 20 Mar 2026hep-ex cs.AI cs.LGcited by 10

On the map: LLM agents and tool use → Web, search, and research agents

Abstract (arXiv)

Large language model-based AI agents are now able to autonomously execute substantial portions of a high energy physics (HEP) analysis pipeline with minimal expert-curated input. Given access to a HEP dataset, an execution framework, and a corpus of prior experimental literature, we find that Claude Code succeeds in automating all stages of a typical analysis: event selection, background estimation, uncertainty quantification, statistical inference, and paper drafting. We argue that the experimental HEP community is underestimating the current capabilities of these systems, and that most proposed agentic workflows are too narrowly scoped or scaffolded to specific analysis structures. We present a proof-of-concept framework, Just Furnish Context (JFC), that integrates autonomous analysis agents with literature-based knowledge retrieval and multi-agent review, and show that this is sufficient to plan, execute, and document a credible high energy physics analysis. We demonstrate this by conducting analyses on open data from ALEPH, DELPHI, and CMS to perform electroweak, QCD, and Higgs boson measurements. We present two of those results in a condensed short paper form -- a CMS Run1 Open Data H→ τ^+τ^- to demonstrate performance on a well-established result, and the first Lund plane measurement on LEP data -- a genuinely novel result and, to our knowledge, the first produced autonomously by an AI agent. Rather than replacing physicists, these tools promise to offload the repetitive technical burden of analysis code development, freeing researchers to focus on physics insight, truly novel method development, and rigorous validation. Given these developments, we advocate for new strategies for how the community trains students, organizes analysis efforts, and allocates human expertise.

Key facts. Cited by 10 papers in the map (data through 7 Oct 2026). Placed in Web, search, and research agents, one of 16 directions in LLM agents and tool use. Builds on 13 of its 85 references that are in the map. First posted on arXiv 20 Mar 2026.

Builds on

13 of 85 references.

Closest ancestors · 5

Same direction, newest first

  1. 2026Agentic AI -- Physicist Collaboration in Experimental Particle Physics: A Proof-of-Concept Measurement with LEP Open Data5 Mar
  2. 2026GRACE: an Agentic AI for Particle Physics Experiment Design and Simulation31 Jan
  3. 2025Automating High Energy Physics Data Analysis with LLM-Powered Agents8 Dec
  4. 2025Agents of Discovery10 Sep
  5. 2024Language agents achieve superhuman synthesis of scientific knowledge10 Sep

Other references · 8

  1. 2023GPT-4 Technical Reportcited by 18,132
  2. 2016XGBoost: A Scalable Tree Boosting Systemcited by 5,120
  3. 2023SWE-bench: Can Language Models Resolve Real-World GitHub Issues?cited by 3,193
  4. 2023Nougat: Neural Optical Understanding for Academic Documentscited by 240
  5. 2024Xiwu: A Basis Flexible and Learnable LLM for High Energy Physicscited by 7
  6. 2026An End-to-end Architecture for Collider Physics and Beyondcited by 5
  7. 2025Pixi: Unified Software Development and Distribution for Robotics and AIcited by 2
  8. 2026CelloAI Benchmarks: Toward Repeatable Evaluation of AI Assistantscited by 2

Built on by

Cited by year (2026 to 7 Oct)

Citing papers per year: 2026: 10.

10 papers.

Similar, not cited

Close in wording, no citation either way

  1. 2026HepScript: A Dual-Use DSL for Human-AI Collaborative Data Analysis Workflows in High-Energy Physics
  2. 2025Agentic Artificial Intelligence for Multistage Physics Experiments at a Large-Scale User Facility Particle Accelerator
  3. 2026From Experimental Limits to Physical Insight: A Retrieval-Augmented Multi-Agent Framework for Interpreting Searches Beyond the Standard Model
  4. 2025PhysMaster: Building an Autonomous AI Physicist for Theoretical and Computational Physics Research
  5. 2026AI Agents, Language, Deep Learning and the Next Revolution in Science
  6. 2025Towards autonomous quantum physics research using LLM agents with access to intelligent tools
  7. 2026Grounded autonomous scrutiny at scale: emergent critique from reproduction of published computational physics papers
  8. 2025Can Theoretical Physics Research Benefit from Language Agents?