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Democratising Clinical AI through Dataset Condensation for Classical Clinical Models

arXiv 2603.09356 ↗First posted 10 Mar 2026cs.LG cs.AI cs.CRcited by 0

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Abstract (arXiv)

Dataset condensation (DC) learns a compact synthetic dataset that enables models to match the performance of full-data training, prioritising utility over distributional fidelity. While typically explored for computational efficiency, DC also holds promise for healthcare data democratisation, especially when paired with differential privacy, allowing synthetic data to serve as a safe alternative to real records. However, existing DC methods rely on differentiable neural networks, limiting their compatibility with widely used clinical models such as decision trees and Cox regression. We address this gap using a differentially private, zero-order optimisation framework that extends DC to non-differentiable models using only function evaluations. Empirical results across six datasets, including both classification and survival tasks, show that the proposed method produces condensed datasets that preserve model utility while providing effective differential privacy guarantees - enabling model-agnostic data sharing for clinical prediction tasks without exposing sensitive patient information.

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References · 18

  1. 2016Communication-Efficient Learning of Deep Networks from Decentralized Datacited by 7,592
  2. 2017A Unified Approach to Interpreting Model Predictionscited by 6,488
  3. 2016Membership Inference Attacks against Machine Learning Modelscited by 2,221
  4. 2020The Future of Digital Health with Federated Learningcited by 625
  5. 2021Tabular Data: Deep Learning is Not All You Needcited by 530
  6. 2021Dataset Condensation with Distribution Matchingcited by 362
  7. 2023Dataset Distillation: A Comprehensive Reviewcited by 126
  8. 2022Privacy for Free: How does Dataset Condensation Help Privacy?cited by 119
  9. 2023Towards Lossless Dataset Distillation via Difficulty-Aligned Trajectory Matchingcited by 118
  10. 2023Generative models improve fairness of medical classifiers under distribution shiftscited by 90
  11. 2024Private Fine-tuning of Large Language Models with Zeroth-order Optimizationcited by 41
  12. 2020Survival regression with accelerated failure time model in XGBoostcited by 37
6 more
  1. 2022No Free Lunch in "Privacy for Free: How does Dataset Condensation Help Privacy"cited by 23
  2. 2019DR-GAN: Conditional Generative Adversarial Network for Fine-Grained Lesion Synthesis on Diabetic Retinopathy Imagescited by 10
  3. 2024A Review on Generative AI Models for Synthetic Medical Text, Time Series, and Longitudinal Datacited by 10
  4. 2024Synthesizing Multimodal Electronic Health Records via Predictive Diffusion Modelscited by 7
  5. 2023Data Encoding For Healthcare Data Democratisation and Information Leakage Preventioncited by 3
  6. 2023Medical records condensation: a roadmap towards healthcare data democratisationcited by 3

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