Mechanistically Guided LoRA Improves Paraphrase Consistency in Medical Vision-Language Models
On the map: Multimodal LLMs / vision-language models → Medical vision-language models
Abstract (arXiv)
Medical Vision-Language Models can give different yes or no answers to rephrasings of the same clinical question. We study this in MedGemma-4B using PSF-Med Sadanandan and Behzadan (2025), which provides paraphrase pairs for systematic consistency evaluation on medical VQA. On MIMIC-CXR binary questions (n = 158), the baseline flip rate is 14.6% and mean margin difference is 1.63 logits. We validate that Gemma Scope 2 Sparse Autoencoders (SAEs) transfer to MedGemma activations, achieving R2 ~= 0.997 on both medical and general text (n = 100 prompts each, p < 0.001 for exceeding a 0.95 threshold). We then fine-tune Low-Rank Adaptation (LoRA) adapters with a combined loss that balances paraphrase consistency with answer accuracy. This combined approach prevents mode collapse that occurs with pure consistency training while reducing flip rate from 14.6% to 4.4% (p = 0.002, two-proportion z-test) and margin difference from 1.63 to 0.33 (79.5% reduction). Accuracy remains stable at 84.2% baseline versus 82.3% after training (-1.9pp, not significant). On PadChest Balanced (n = 250), flip rate drops from 13.6% to 7.8%, mean margin difference drops from 1.08 to 0.35 (67.9% reduction), and accuracy increases from 66.4% to 69.4%. A layer-range ablation shows that early layers reduce margin differences more than mechanistically selected middle layers.
Key facts. Cited by 2 papers in the map (data through 7 Oct 2026). Placed in Medical vision-language models, one of 16 directions in Multimodal LLMs / vision-language models. Builds on 10 of its 25 references that are in the map. First posted on arXiv 24 Feb 2026.
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- 2022Locating and Editing Factual Associations in GPTcited by 2,609
- 2023Sparse Autoencoders Find Highly Interpretable Features in Language Modelscited by 1,359
- 2019Publicly Available Clinical BERT Embeddingscited by 995
- 2020Beyond Accuracy: Behavioral Testing of NLP models with CheckListcited by 979
- 2021SLAKE: A Semantically-Labeled Knowledge-Enhanced Dataset for Medical Visual Question Answeringcited by 444
- 2024Sparse Feature Circuits: Discovering and Editing Interpretable Causal Graphs in Language Modelscited by 412
- 2021Measuring and Improving Consistency in Pretrained Language Modelscited by 361
- 2019PadChest: A large chest x-ray image dataset with multi-label annotated reportscited by 308
- 2019Cycle-Consistency for Robust Visual Question Answeringcited by 105
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- 2026PSF-Med: Measuring and Explaining Paraphrase Sensitivity in Medical Vision Language Models
- 2025Knowing or Guessing? Robust Medical Visual Question Answering via Joint Consistency and Contrastive Learning
- 2024The Limited Impact of Medical Adaptation of Large Language and Vision-Language Models
- 2026Consistent but Dangerous: Per-Sample Safety Classification Reveals False Reliability in Medical Vision-Language Models
- 2026Do Medical Vision Language Models Actually See? A Counterfactual Grounding Framework and Hard-Negative Contrastive Training for Visually-Reliant Medical VLMs
- 2025Uncertainty-Driven Expert Control: Enhancing the Reliability of Medical Vision-Language Models
- 2024Fusion of Domain-Adapted Vision and Language Models for Medical Visual Question Answering
- 2026To Agree or To Be Right? The Grounding-Sycophancy Tradeoff in Medical Vision-Language Models