Mirror: A Multi-Agent System for AI-Assisted Ethics Review
On the map: LLM agents and tool use → General LLM agent frameworks and benchmarks
Abstract (arXiv)
Ethics review is a foundational mechanism of modern research governance, yet contemporary systems face increasing strain as ethical risks arise as structural consequences of large-scale, interdisciplinary scientific practice. The demand for consistent and defensible decisions under heterogeneous risk profiles exposes limitations in institutional review capacity rather than in the legitimacy of ethics oversight. Recent advances in large language models (LLMs) offer new opportunities to support ethics review, but their direct application remains limited by insufficient ethical reasoning capability, weak integration with regulatory structures, and strict privacy constraints on authentic review materials. In this work, we introduce Mirror, an agentic framework for AI-assisted ethical review that integrates ethical reasoning, structured rule interpretation, and multi-agent deliberation within a unified architecture. At its core is EthicsLLM, a foundational model fine-tuned on EthicsQA, a specialized dataset of 41K question-chain-of-thought-answer triples distilled from authoritative ethics and regulatory corpora. EthicsLLM provides detailed normative and regulatory understanding, enabling Mirror to operate in two complementary modes. Mirror-ER (expedited Review) automates expedited review through an executable rule base that supports efficient and transparent compliance checks for minimal-risk studies. Mirror-CR (Committee Review) simulates full-board deliberation through coordinated interactions among expert agents, an ethics secretary agent, and a principal investigator agent, producing structured, committee-level assessments across ten ethical dimensions. Empirical evaluations demonstrate that Mirror significantly improves the quality, consistency, and professionalism of ethics assessments compared with strong generalist LLMs.
Key facts. No citing papers in the map yet (data through 7 Oct 2026). Placed in General LLM agent frameworks and benchmarks, one of 16 directions in LLM agents and tool use. Builds on 8 of its 27 references that are in the map. First posted on arXiv 9 Feb 2026.
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