A Diffusion-Based Generative Prior Approach to Sparse-view Computed Tomography
On the map: Diffusion models → Medical imaging and segmentation
Abstract (arXiv)
The reconstruction of X-rays CT images from sparse or limited-angle geometries is a highly challenging task. The lack of data typically results in artifacts in the reconstructed image and may even lead to object distortions. For this reason, the use of deep generative models in this context has great interest and potential success. In the Deep Generative Prior (DGP) framework, the use of diffusion-based generative models is combined with an iterative optimization algorithm for the reconstruction of CT images from sinograms acquired under sparse geometries, to maintain the explainability of a model-based approach while introducing the generative power of a neural network. There are therefore several aspects that can be further investigated within these frameworks to improve reconstruction quality, such as image generation, the model, and the iterative algorithm used to solve the minimization problem, for which we propose modifications with respect to existing approaches. The results obtained even under highly sparse geometries are very promising, although further research is clearly needed in this direction.
Key facts. No citing papers in the map yet (data through 7 Oct 2026). Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models. Builds on 28 of its 51 references that are in the map. First posted on arXiv 11 Feb 2026.
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28 of 51 references.
Closest ancestors · 4
Same direction, newest first
- 2024MSDiff: Multi-Scale Diffusion Model for Ultra-Sparse View CT Reconstruction9 May
- 2022Solving 3D Inverse Problems using Pre-trained 2D Diffusion Models19 Nov
- 2022Diffusion Models for Medical Image Analysis: A Comprehensive Survey14 Nov
- 2021Solving Inverse Problems in Medical Imaging with Score-Based Generative Models15 Nov
Other references · 24
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- 2020Exploiting Deep Generative Prior for Versatile Image Restoration and Manipulationcited by 225
12 more
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- 2017A Review of Convolutional Neural Networks for Inverse Problems in Imagingcited by 81
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- 2023Image Restoration by Denoising Diffusion Models with Iteratively Preconditioned Guidancecited by 43
- 2018Physics-Based Generative Adversarial Models for Image Restoration and Beyondcited by 37
- 2018Modeling Sparse Deviations for Compressed Sensing using Generative Modelscited by 33
- 2021A survey on Variational Autoencoders from a GreenAI perspectivecited by 22
- 2021Regularising Inverse Problems with Generative Machine Learning Modelscited by 22
- 2022To be or not to be stable, that is the question: understanding neural networks for inverse problemscited by 8
- 2022Image Embedding for Denoising Generative Modelscited by 7
- 2023Constrained Regularization by Denoising with Automatic Parameter Selectioncited by 6
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- 2026Towards reconstructing experimental sparse-view X-ray CT data with diffusion models
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- 2025Physics-Guided Null-Space Diffusion with Sparse Masking for Corrective Sparse-View CT Reconstruction
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- 2023Data-iterative Optimization Score Model for Stable Ultra-Sparse-View CT Reconstruction