Demo: Generative AI helps Radiotherapy Planning with User Preference
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Abstract (arXiv)
Radiotherapy planning is a highly complex process that often varies significantly across institutions and individual planners. Most existing deep learning approaches for 3D dose prediction rely on reference plans as ground truth during training, which can inadvertently bias models toward specific planning styles or institutional preferences. In this study, we introduce a novel generative model that predicts 3D dose distributions based solely on user-defined preference flavors. These customizable preferences enable planners to prioritize specific trade-offs between organs-at-risk (OARs) and planning target volumes (PTVs), offering greater flexibility and personalization. Designed for seamless integration with clinical treatment planning systems, our approach assists users in generating high-quality plans efficiently. Comparative evaluations demonstrate that our method can surpasses the Varian RapidPlan model in both adaptability and plan quality in some scenarios.
Key facts. Cited by 2 papers in the map (data through 7 Oct 2026). Builds on 14 of its 29 references that are in the map. First posted on arXiv 8 Dec 2025.
Builds on
14 of 29 references.
References · 14
- 2020Denoising Diffusion Probabilistic Modelscited by 20,851
- 2021High-Resolution Image Synthesis with Latent Diffusion Modelscited by 18,694
- 2022Hierarchical Text-Conditional Image Generation with CLIP Latentscited by 6,539
- 2017Neural Discrete Representation Learningcited by 4,650
- 2025Wan: Open and Advanced Large-Scale Video Generative Modelscited by 2,536
- 2017Arbitrary Style Transfer in Real-time with Adaptive Instance Normalizationcited by 1,998
- 2020Understanding Contrastive Representation Learning through Alignment and Uniformity on the Hyperspherecited by 1,393
- 2022MONAI: An open-source framework for deep learning in healthcarecited by 438
- 2023MedNeXt: Transformer-driven Scaling of ConvNets for Medical Image Segmentationcited by 161
- 2020OpenKBP: The open-access knowledge-based planning grand challengecited by 30
- 2023DoseDiff: Distance-aware Diffusion Model for Dose Prediction in Radiotherapycited by 10
- 2024Multi-Agent Reinforcement Learning Meets Leaf Sequencing in Radiotherapycited by 6
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Citing papers per year: 2026: 2.
2 papers.