mlsanityData to 7 Oct 2026

47B Mixture-of-Experts Beats 671B Dense Models on Chinese Medical Examinations

arXiv 2511.21701 ↗First posted 16 Nov 2025cs.CL cs.LGcited by 1

On the map: Mixture-of-experts → Medical and biomedical MoE

Abstract (arXiv)

The rapid advancement of large language models(LLMs) has prompted significant interest in their potential applications in medical domains. This paper presents a comprehensive benchmark evaluation of 27 state-of-the-art LLMs on Chinese medical examination questions, encompassing seven medical specialties across two professional levels. We introduce a robust evaluation framework that assesses model performance on 2,800 carefully curated questions from cardiovascular, gastroenterology, hematology, infectious diseases, nephrology, neurology, and respiratory medicine domains. Our dataset distinguishes between attending physician and senior physician difficulty levels, providing nuanced insights into model capabilities across varying complexity. Our empirical analysis reveals substantial performance variations among models, with Mixtral-8x7B achieving the highest overall accuracy of 74.25%, followed by DeepSeek-R1-671B at 64.07%. Notably, we observe no consistent correlation between model size and performance, as evidenced by the strong performance of smaller mixture-of-experts architectures. The evaluation demonstrates significant performance gaps between medical specialties, with models generally performing better on cardiovascular and neurology questions compared to gastroenterology and nephrology domains. Furthermore, our analysis indicates minimal performance degradation between attending and senior physician levels for top-performing models, suggesting robust generalization capabilities. This benchmark provides critical insights for the deployment of LLMs in medical education and clinical decision support systems, highlighting both the promise and current limitations of these technologies in specialized medical contexts.

Key facts. Cited by 1 paper in the map (data through 7 Oct 2026). Placed in Medical and biomedical MoE, one of 12 directions in Mixture-of-experts. Builds on 20 of its 40 references that are in the map. First posted on arXiv 16 Nov 2025.

Builds on

20 of 40 references.

References · 20

  1. 2020Language Models are Few-Shot Learnerscited by 32,199
  2. 2023GPT-4 Technical Reportcited by 18,132
  3. 2022Large Language Models Encode Clinical Knowledgecited by 1,807
  4. 2024Mixtral of Expertscited by 1,785
  5. 2020What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Examscited by 1,324
  6. 2019PubMedQA: A Dataset for Biomedical Research Question Answeringcited by 1,271
  7. 2020Domain-Specific Language Model Pretraining for Biomedical Natural Language Processingcited by 996
  8. 2024DeepSeekMoE: Towards Ultimate Expert Specialization in Mixture-of-Experts Language Modelscited by 834
  9. 2023Capabilities of GPT-4 on Medical Challenge Problemscited by 630
  10. 2022MedMCQA : A Large-scale Multi-Subject Multi-Choice Dataset for Medical domain Question Answeringcited by 525
  11. 2023Towards Expert-Level Medical Question Answering with Large Language Modelscited by 382
  12. 2024BioMistral: A Collection of Open-Source Pretrained Large Language Models for Medical Domainscited by 299
8 more
  1. 2023MEDITRON-70B: Scaling Medical Pretraining for Large Language Modelscited by 272
  2. 2023HuatuoGPT, towards Taming Language Model to Be a Doctorcited by 211
  3. 2023HuaTuo: Tuning LLaMA Model with Chinese Medical Knowledgecited by 161
  4. 2023DoctorGLM: Fine-tuning your Chinese Doctor is not a Herculean Taskcited by 130
  5. 2023Zhongjing: Enhancing the Chinese Medical Capabilities of Large Language Model through Expert Feedback and Real-world Multi-turn Dialoguecited by 118
  6. 2021CBLUE: A Chinese Biomedical Language Understanding Evaluation Benchmarkcited by 99
  7. 2023PMC-LLaMA: Towards Building Open-source Language Models for Medicinecited by 87
  8. 2023MedAlign: A Clinician-Generated Dataset for Instruction Following with Electronic Medical Recordscited by 54

Built on by

Cited by year (2026 to 7 Oct)

Citing papers per year: 2026: 1.

1 paper.

Similar, not cited

Close in wording, no citation either way

  1. 2023Benchmarking Large Language Models on CMExam -- A Comprehensive Chinese Medical Exam Dataset
  2. 2023MedBench: A Large-Scale Chinese Benchmark for Evaluating Medical Large Language Models
  3. 2024Development and bilingual evaluation of Japanese medical large language model within reasonably low computational resources
  4. 2024MedExpQA: Multilingual Benchmarking of Large Language Models for Medical Question Answering
  5. 2025MedBench v4: A Robust and Scalable Benchmark for Evaluating Chinese Medical Language Models, Multimodal Models, and Intelligent Agents
  6. 2025MTCMB: A Multi-Task Benchmark Framework for Evaluating LLMs on Knowledge, Reasoning, and Safety in Traditional Chinese Medicine
  7. 2026Assessing Large Language Models for Medical QA: Zero-Shot and LLM-as-a-Judge Evaluation
  8. 2025PersianMedQA: Evaluating Large Language Models on a Persian-English Bilingual Medical Question Answering Benchmark