MedMambaLite: Hardware-Aware Mamba for Medical Image Classification
On the map: State-space sequence models (S4, Mamba) → Mamba for medical image analysis
Abstract (arXiv)
AI-powered medical devices have driven the need for real-time, on-device inference such as biomedical image classification. Deployment of deep learning models at the edge is now used for applications such as anomaly detection and classification in medical images. However, achieving this level of performance on edge devices remains challenging due to limitations in model size and computational capacity. To address this, we present MedMambaLite, a hardware-aware Mamba-based model optimized through knowledge distillation for medical image classification. We start with a powerful MedMamba model, integrating a Mamba structure for efficient feature extraction in medical imaging. We make the model lighter and faster in training and inference by modifying and reducing the redundancies in the architecture. We then distill its knowledge into a smaller student model by reducing the embedding dimensions. The optimized model achieves 94.5% overall accuracy on 10 MedMNIST datasets. It also reduces parameters 22.8x compared to MedMamba. Deployment on an NVIDIA Jetson Orin Nano achieves 35.6 GOPS/J energy per inference. This outperforms MedMamba by 63% improvement in energy per inference.
Key facts. Cited by 4 papers in the map (data through 7 Oct 2026). Placed in Mamba for medical image analysis, one of 10 directions in State-space sequence models (S4, Mamba). Builds on 22 of its 41 references that are in the map. First posted on arXiv 7 Aug 2025.
Builds on
22 of 41 references.
Closest ancestors · 3
Same direction, newest first
- 2024A Comprehensive Survey of Mamba Architectures for Medical Image Analysis: Classification, Segmentation, Restoration and Beyond3 Oct
- 2024MedMamba: Vision Mamba for Medical Image Classification6 Mar
- 2024VM-UNet: Vision Mamba UNet for Medical Image Segmentation4 Feb
Other references · 19
- 2015Deep Residual Learning for Image Recognitioncited by 51,809
- 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,604
- 2015Distilling the Knowledge in a Neural Networkcited by 10,076
- 2023Mamba: Linear-Time Sequence Modeling with Selective State Spacescited by 4,616
- 2020Knowledge Distillation: A Surveycited by 1,578
- 2024Vision Mamba: Efficient Visual Representation Learning with Bidirectional State Space Modelcited by 1,051
- 2024VMamba: Visual State Space Modelcited by 955
- 2021MedMNIST v2 -- A large-scale lightweight benchmark for 2D and 3D biomedical image classificationcited by 682
- 2018Aleatoric uncertainty estimation with test-time augmentation for medical image segmentation with convolutional neural networkscited by 278
- 2024MambaVision: A Hybrid Mamba-Transformer Vision Backbonecited by 222
- 2020PAD-UFES-20: a skin lesion dataset composed of patient data and clinical images collected from smartphonescited by 116
- 2023MedViT: A Robust Vision Transformer for Generalized Medical Image Classificationcited by 89
7 more
- 2018Recalibrating Fully Convolutional Networks with Spatial and Channel 'Squeeze & Excitation' Blockscited by 75
- 2025GenAI at the Edge: Comprehensive Survey on Empowering Edge Devicescited by 14
- 2023Squeezed Edge YOLO: Onboard Object Detection on Edge Devicescited by 8
- 2024TinyM2Net-V3: Memory-Aware Compressed Multimodal Deep Neural Networks for Sustainable Edge Deploymentcited by 4
- 2025MambaLiteSR: Image Super-Resolution with Low-Rank Mamba using Knowledge Distillationcited by 3
- 2025EDEN: Entorhinal Driven Egocentric Navigation Toward Robotic Deploymentcited by 3
- 2025MedCL: Learning Consistent Anatomy Distribution for Scribble-supervised Medical Image Segmentationcited by 1
Built on by
Citing papers per year: 2025: 1; 2026: 3.
4 papers.
- 2025EdgeNavMamba: Mamba Optimized Object Detection for Energy Efficient Edge Devicescited by 2
- 2026Efficient Deep Learning for Medical Imaging: Bridging the Gap Between High-Performance AI and Clinical Deploymentcited by 1
- 2026TinyNeRV: Compact Neural Video Representations via Capacity Scaling, Distillation, and Low-Precision Inferencecited by 0
- 2026Nutri-ATLAS: Embodied Agent for Tabulated Lookup and Assistance for Smarter nutritioncited by 0
- 2026Nutri-ATLAS: Embodied Agent for Tabulated Lookup and Assistance for Smarter nutrition26 Sep 2026
- 2026TinyNeRV: Compact Neural Video Representations via Capacity Scaling, Distillation, and Low-Precision Inference10 Apr 2026
- 2026Efficient Deep Learning for Medical Imaging: Bridging the Gap Between High-Performance AI and Clinical Deployment31 Jan 2026
- 2025EdgeNavMamba: Mamba Optimized Object Detection for Energy Efficient Edge Devices16 Oct 2025
Similar, not cited
Close in wording, no citation either way
- 2026Is Mamba Reliable for Medical Imaging?
- 2024Mamba-UNet: UNet-Like Pure Visual Mamba for Medical Image Segmentation
- 2025SpectMamba: Integrating Frequency and State Space Models for Enhanced Medical Image Detection
- 2025MobileViM: A Light-weight and Dimension-independent Vision Mamba for 3D Medical Image Analysis
- 2025MedVKAN: Efficient Feature Extraction with Mamba and KAN for Medical Image Segmentation
- 2025MambaVesselNet++: A Hybrid CNN-Mamba Architecture for Medical Image Segmentation
- 2025EVM-Fusion: An Explainable Vision Mamba Architecture with Neural Algorithmic Fusion
- 2024nnMamba: 3D Biomedical Image Segmentation, Classification and Landmark Detection with State Space Model