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ARMR: Adaptively Responsive Network for Medication Recommendation

arXiv 2507.04428 ↗First posted 6 Jul 2025cs.AI cs.LGcited by 0

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Abstract (arXiv)

Medication recommendation is a crucial task in healthcare, especially for patients with complex medical conditions. However, existing methods often struggle to effectively balance the reuse of historical medications with the introduction of new drugs in response to the changing patient conditions. In order to address this challenge, we propose an Adaptively Responsive network for Medication Recommendation (ARMR), a new method which incorporates 1) a piecewise temporal learning component that distinguishes between recent and distant patient history, enabling more nuanced temporal understanding, and 2) an adaptively responsive mechanism that dynamically adjusts attention to new and existing drugs based on the patient's current health state and medication history. Experiments on the MIMIC-III and MIMIC-IV datasets indicate that ARMR has better performance compared with the state-of-the-art baselines in different evaluation metrics, which contributes to more personalized and accurate medication recommendations. The source code is publicly avaiable at: https://github.com/seucoin/armr2.

Key facts. No citing papers in the map yet (data through 7 Oct 2026). Builds on 12 of its 30 references that are in the map. First posted on arXiv 6 Jul 2025.

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References · 12

  1. 2016Layer Normalizationcited by 5,579
  2. 2023Mamba: Linear-Time Sequence Modeling with Selective State Spacescited by 4,616
  3. 2016RETAIN: An Interpretable Predictive Model for Healthcare using Reverse Time Attention Mechanismcited by 344
  4. 2015Doctor AI: Predicting Clinical Events via Recurrent Neural Networkscited by 205
  5. 2019Pre-training of Graph Augmented Transformers for Medication Recommendationcited by 124
  6. 2018GAMENet: Graph Augmented MEmory Networks for Recommending Medication Combinationcited by 79
  7. 2021SafeDrug: Dual Molecular Graph Encoders for Recommending Effective and Safe Drug Combinationscited by 51
  8. 2021Change Matters: Medication Change Prediction with Recurrent Residual Networkscited by 37
  9. 2022Conditional Generation Net for Medication Recommendationcited by 28
  10. 2018Dual Memory Neural Computer for Asynchronous Two-view Sequential Learningcited by 27
  11. 2024Large Language Model Distilling Medication Recommendation Modelcited by 25
  12. 2016A Physician Advisory System for Chronic Heart Failure Management Based on Knowledge Patternscited by 13

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