mlsanityData to 14 Oct 2026

Discovering Pathology Rationale and Token Allocation for Efficient Multimodal Pathology Reasoning

arXiv 2505.15687 ↗First posted 21 May 2025cs.CV cs.AIcited by 4

Not on the map. Why?

Abstract (arXiv)

Multimodal pathological image understanding has garnered widespread interest due to its potential to improve diagnostic accuracy and enable personalized treatment through integrated visual and textual data. However, existing methods exhibit limited reasoning capabilities, which hamper their ability to handle complex diagnostic scenarios. Additionally, the enormous size of pathological images leads to severe computational burdens, further restricting their practical deployment. To address these limitations, we introduce a novel bilateral reinforcement learning framework comprising two synergistic branches. One reinforcement branch enhances the reasoning capability by enabling the model to learn task-specific decision processes, i.e., pathology rationales, directly from labels without explicit reasoning supervision. While the other branch dynamically allocates a tailored number of tokens to different images based on both their visual content and task context, thereby optimizing computational efficiency. We apply our method to various pathological tasks such as visual question answering, cancer subtyping, and lesion detection. Extensive experiments show an average +41.7 absolute performance improvement with 70.3% lower inference costs over the base models, achieving both reasoning accuracy and computational efficiency.

Key facts. Cited by 4 papers in the map (data through 14 Oct 2026). Builds on 28 of its 43 references that are in the map. First posted on arXiv 21 May 2025.

Builds on

28 of 43 references.

References · 28

  1. 2019PyTorch: An Imperative Style, High-Performance Deep Learning Librarycited by 20,305
  2. 2017Proximal Policy Optimization Algorithmscited by 15,215
  3. 2023Visual Instruction Tuningcited by 7,869
  4. 2025DeepSeek-R1: Incentivizing Reasoning Capability in LLMs via Reinforcement Learningcited by 6,330
  5. 2025Qwen2.5-VL Technical Reportcited by 5,587
  6. 2023Improved Baselines with Visual Instruction Tuningcited by 4,418
  7. 2018Attention-based Deep Multiple Instance Learningcited by 1,095
  8. 2024Cambrian-1: A Fully Open, Vision-Centric Exploration of Multimodal LLMscited by 838
  9. 2024Eyes Wide Shut? Exploring the Visual Shortcomings of Multimodal LLMscited by 735
  10. 2025Visual-RFT: Visual Reinforcement Fine-Tuningcited by 513
  11. 2020PathVQA: 30000+ Questions for Medical Visual Question Answeringcited by 475
  12. 2018Deep Learning for Generic Object Detection: A Surveycited by 392
16 more
  1. 2023Quilt-1M: One Million Image-Text Pairs for Histopathologycited by 194
  2. 2025Med-R1: Reinforcement Learning for Generalizable Medical Reasoning in Vision-Language Modelscited by 144
  3. 2024BiomedParse: a biomedical foundation model for image parsing of everything everywhere all at oncecited by 111
  4. 2024MambaMIL: Enhancing Long Sequence Modeling with Sequence Reordering in Computational Pathologycited by 88
  5. 2018MILD-Net: Minimal Information Loss Dilated Network for Gland Instance Segmentation in Colon Histology Imagescited by 87
  6. 2023Quilt-LLaVA: Visual Instruction Tuning by Extracting Localized Narratives from Open-Source Histopathology Videoscited by 86
  7. 2016DCAN: Deep Contour-Aware Networks for Accurate Gland Segmentationcited by 84
  8. 2024Foundation Model for Advancing Healthcare: Challenges, Opportunities, and Future Directionscited by 77
  9. 2024A Multimodal Knowledge-enhanced Whole-slide Pathology Foundation Modelcited by 59
  10. 2023PathAsst: A Generative Foundation AI Assistant Towards Artificial General Intelligence of Pathologycited by 57
  11. 2024PathMMU: A Massive Multimodal Expert-Level Benchmark for Understanding and Reasoning in Pathologycited by 43
  12. 2024In-context learning enables multimodal large language models to classify cancer pathology imagescited by 38
  13. 2024CPath-Omni: A Unified Multimodal Foundation Model for Patch and Whole Slide Image Analysis in Computational Pathologycited by 34
  14. 2021UniToPatho, a labeled histopathological dataset for colorectal polyps classification and adenoma dysplasia gradingcited by 33
  15. 2024Towards A Generalizable Pathology Foundation Model via Unified Knowledge Distillationcited by 31
  16. 2024Vim4Path: Self-Supervised Vision Mamba for Histopathology Imagescited by 19

Built on by

Cited by year (2026 to 14 Oct)

Citing papers per year: 2025: 2; 2026: 2.

4 papers.

Similar, not cited

Close in wording, no citation either way

  1. 2026ReinPath: A Multimodal Reinforcement Learning Approach for Pathology
  2. 2025Patho-R1: A Multimodal Reinforcement Learning-Based Pathology Expert Reasoner
  3. 2025PathVLM-R1: A Reinforcement Learning-Driven Reasoning Model for Pathology Visual-Language Tasks
  4. 2025A Versatile Pathology Co-pilot via Reasoning Enhanced Multimodal Large Language Model
  5. 2025PathFound: An Agentic Multimodal Model Activating Evidence-seeking Pathological Diagnosis
  6. 2026See, Measure, and Reason: Learning Visually Grounded Reasoning in Pathology
  7. 2026PathReasoner-R1: Instilling Structured Reasoning into Pathology Vision-Language Model via Knowledge-Guided Policy Optimization
  8. 2026Multimodal Model for Computational Pathology:Representation Learning and Image Compression