KDH-MLTC: Knowledge Distillation for Healthcare Multi-Label Text Classification
On the map: Knowledge distillation → Knowledge distillation for LLMs
Abstract (arXiv)
The increasing volume of healthcare textual data requires computationally efficient, yet highly accurate classification approaches able to handle the nuanced and complex nature of medical terminology. This research presents Knowledge Distillation for Healthcare Multi-Label Text Classification (KDH-MLTC), a framework leveraging model compression and Large Language Models (LLMs). The proposed approach addresses conventional healthcare Multi-Label Text Classification (MLTC) challenges by integrating knowledge distillation and sequential fine-tuning, subsequently optimized through Particle Swarm Optimization (PSO) for hyperparameter tuning. KDH-MLTC transfers knowledge from a more complex teacher LLM (i.e., BERT) to a lighter student LLM (i.e., DistilBERT) through sequential training adapted to MLTC that preserves the teacher's learned information while significantly reducing computational requirements. As a result, the classification is enabled to be conducted locally, making it suitable for healthcare textual data characterized by sensitivity and, therefore, ensuring HIPAA compliance. The experiments conducted on three medical literature datasets of different sizes, sampled from the Hallmark of Cancer (HoC) dataset, demonstrate that KDH-MLTC achieves superior performance compared to existing approaches, particularly for the largest dataset, reaching an F1 score of 82.70%. Additionally, statistical validation and an ablation study are carried out, proving the robustness of KDH-MLTC. Furthermore, the PSO-based hyperparameter optimization process allowed the identification of optimal configurations. The proposed approach contributes to healthcare text classification research, balancing efficiency requirements in resource-constrained healthcare settings with satisfactory accuracy demands.
Key facts. Cited by 2 papers in the map (data through 14 Oct 2026). Placed in Knowledge distillation for LLMs, one of 12 directions in Knowledge distillation. Builds on 15 of its 33 references that are in the map. First posted on arXiv 12 May 2025.
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15 of 33 references.
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Other references · 14
- 2018BERT: Pre-training of Deep Bidirectional Transformers for Language Understandingcited by 40,399
- 2019RoBERTa: A Robustly Optimized BERT Pretraining Approachcited by 13,372
- 2015Distilling the Knowledge in a Neural Networkcited by 10,324
- 2019DistilBERT, a distilled version of BERT: smaller, faster, cheaper and lightercited by 4,307
- 2019ALBERT: A Lite BERT for Self-supervised Learning of Language Representationscited by 2,790
- 2019BioBERT: a pre-trained biomedical language representation model for biomedical text miningcited by 1,947
- 2014FitNets: Hints for Thin Deep Netscited by 1,653
- 2020Knowledge Distillation: A Surveycited by 1,603
- 2019TinyBERT: Distilling BERT for Natural Language Understandingcited by 1,167
- 2019Relational Knowledge Distillationcited by 889
- 2019ClinicalBERT: Modeling Clinical Notes and Predicting Hospital Readmissioncited by 493
- 2020Comparing BERT against traditional machine learning text classificationcited by 46
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Citing papers per year: 2025: 1; 2026: 1.
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- 2023Distilling Large Language Models for Biomedical Knowledge Extraction: A Case Study on Adverse Drug Events
- 2025Benchmarking Open-Source Large Language Models on Healthcare Text Classification Tasks
- 2024Performance-Guided LLM Knowledge Distillation for Efficient Text Classification at Scale
- 2025CKD-EHR:Clinical Knowledge Distillation for Electronic Health Records