MedRep: Medical Concept Representation for General Electronic Health Record Foundation Models
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Abstract (arXiv)
Electronic health record (EHR) foundation models have been an area ripe for exploration with their improved performance in various medical tasks. Despite the rapid advances, there exists a fundamental limitation: Processing unseen medical codes out of vocabulary. This problem limits the generalizability of EHR foundation models and the integration of models trained with different vocabularies. To alleviate this problem, we propose a set of novel medical concept representations (MedRep) for EHR foundation models based on the observational medical outcome partnership (OMOP) common data model (CDM). For concept representation learning, we enrich the information of each concept with a minimal definition through large language model (LLM) prompts and complement the text-based representations through the graph ontology of OMOP vocabulary. Our approach outperforms the vanilla EHR foundation model and the model with a previously introduced medical code tokenizer in diverse prediction tasks. We also demonstrate the generalizability of MedRep through external validation.
Key facts. Cited by 4 papers in the map (data through 14 Oct 2026). Builds on 23 of its 60 references that are in the map. First posted on arXiv 11 Apr 2025.
Builds on
23 of 60 references.
References · 23
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11 more
- 2019BEHRT: Transformer for Electronic Health Recordscited by 263
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Built on by
Citing papers per year: 2025: 1; 2026: 3.
4 papers.
- 2025Count-Based Approaches Remain Strong: A Benchmark Against Transformer and LLM Pipelines on Structured EHRcited by 3
- 2026A General Multimodal Probing Framework for Data Fusion and Prediction with Frozen Large Language Models: Evidence from Multimodal EHR Datacited by 0
- 2026GLoC-EHR: Evidence-Cited Clinical Reasoning over Global Context and Local EHR Eventscited by 0
- 2026Bridging the EHR Divide: Asymmetric Contrastive Learning for Cross-National Medical Representation Transfercited by 0
- 2026Bridging the EHR Divide: Asymmetric Contrastive Learning for Cross-National Medical Representation Transfer4 Oct 2026
- 2026GLoC-EHR: Evidence-Cited Clinical Reasoning over Global Context and Local EHR Events1 Oct 2026
- 2026A General Multimodal Probing Framework for Data Fusion and Prediction with Frozen Large Language Models: Evidence from Multimodal EHR Data27 Jun 2026
- 2025Count-Based Approaches Remain Strong: A Benchmark Against Transformer and LLM Pipelines on Structured EHR2 Nov 2025