mlsanityData to 14 Oct 2026

A Reality Check of Vision-Language Pre-training in Radiology: Have We Progressed Using Text?

arXiv 2504.05227 ↗First posted 7 Apr 2025cs.CVcited by 2

On the map: Multimodal LLMs / vision-language models → Medical vision-language models

Abstract (arXiv)

Vision-language pre-training has recently gained popularity as it allows learning rich feature representations using large-scale data sources. This paradigm has quickly made its way into the medical image analysis community. In particular, there is an impressive amount of recent literature developing vision-language models for radiology. However, the available medical datasets with image-text supervision are scarce, and medical concepts are fine-grained, involving expert knowledge that existing vision-language models struggle to encode. In this paper, we propose to take a prudent step back from the literature and revisit supervised, unimodal pre-training, using fine-grained labels instead. We conduct an extensive comparison demonstrating that unimodal pre-training is highly competitive and better suited to integrating heterogeneous data sources. Our results also question the potential of recent vision-language models for open-vocabulary generalization, which have been evaluated using optimistic experimental settings. Finally, we study novel alternatives to better integrate fine-grained labels and noisy text supervision.

Key facts. Cited by 2 papers in the map (data through 14 Oct 2026). Placed in Medical vision-language models, one of 16 directions in Multimodal LLMs / vision-language models. Builds on 40 of its 58 references that are in the map. First posted on arXiv 7 Apr 2025.

Builds on

40 of 58 references.

Closest ancestors · 3

Same direction, newest first

  1. 2024Few-shot Adaptation of Medical Vision-Language Models5 Sep
  2. 2023CXR-CLIP: Toward Large Scale Chest X-ray Language-Image Pre-training20 Oct
  3. 2023A Foundation Language-Image Model of the Retina (FLAIR): Encoding Expert Knowledge in Text Supervision15 Aug

Other references · 37

  1. 2015Deep Residual Learning for Image Recognitioncited by 52,096
  2. 2021Learning Transferable Visual Models From Natural Language Supervisioncited by 33,744
  3. 2021Scaling Up Visual and Vision-Language Representation Learning With Noisy Text Supervisioncited by 3,864
  4. 2020Supervised Contrastive Learningcited by 2,829
  5. 2019CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparisoncited by 1,423
  6. 2017A Survey on Deep Learning in Medical Image Analysiscited by 1,186
  7. 2019Publicly Available Clinical BERT Embeddingscited by 1,002
  8. 2017ChestX-ray8: Hospital-scale Chest X-ray Database and Benchmarks on Weakly-Supervised Classification and Localization of Common Thorax Diseasescited by 972
  9. 2020Contrastive Learning of Medical Visual Representations from Paired Images and Textcited by 641
  10. 2022MedCLIP: Contrastive Learning from Unpaired Medical Images and Textcited by 570
  11. 2019Transfusion: Understanding Transfer Learning for Medical Imagingcited by 368
  12. 2022Making the Most of Text Semantics to Improve Biomedical Vision--Language Processingcited by 339
25 more
  1. 2020CheXbert: Combining Automatic Labelers and Expert Annotations for Accurate Radiology Report Labeling Using BERTcited by 337
  2. 2021Big Self-Supervised Models Advance Medical Image Classificationcited by 320
  3. 2021RadGraph: Extracting Clinical Entities and Relations from Radiology Reportscited by 319
  4. 2019PadChest: A large chest x-ray image dataset with multi-label annotated reportscited by 309
  5. 2023What's "up" with vision-language models? Investigating their struggle with spatial reasoningcited by 254
  6. 2020VinDr-CXR: An open dataset of chest X-rays with radiologist's annotationscited by 239
  7. 2020Can AI help in screening Viral and COVID-19 pneumonia?cited by 200
  8. 2022Multi-Granularity Cross-modal Alignment for Generalized Medical Visual Representation Learningcited by 159
  9. 2023MedKLIP: Medical Knowledge Enhanced Language-Image Pre-Training in Radiologycited by 149
  10. 2023On the Challenges and Perspectives of Foundation Models for Medical Image Analysiscited by 135
  11. 2023Knowledge-enhanced Visual-Language Pre-training on Chest Radiology Imagescited by 128
  12. 2021Generalized Radiograph Representation Learning via Cross-supervision between Images and Free-text Radiology Reportscited by 80
  13. 2017NegBio: a high-performance tool for negation and uncertainty detection in radiology reportscited by 79
  14. 2023Advancing Radiograph Representation Learning with Masked Record Modelingcited by 75
  15. 2020Why Do Better Loss Functions Lead to Less Transferable Features?cited by 73
  16. 2023A Closer Look at the Few-Shot Adaptation of Large Vision-Language Modelscited by 67
  17. 2022Long-Tailed Classification of Thorax Diseases on Chest X-Ray: A New Benchmark Studycited by 45
  18. 2023MultiTalent: A Multi-Dataset Approach to Medical Image Segmentationcited by 45
  19. 2021Revisiting the Transferability of Supervised Pretraining: an MLP Perspectivecited by 36
  20. 2021Rethinking Supervised Pre-training for Better Downstream Transferringcited by 35
  21. 2020CheXpert++: Approximating the CheXpert labeler for Speed,Differentiability, and Probabilistic Outputcited by 23
  22. 2022No Reason for No Supervision: Improved Generalization in Supervised Modelscited by 23
  23. 2022When are Lemons Purple? The Concept Association Bias of Vision-Language Modelscited by 23
  24. 2023Towards Foundation Models and Few-Shot Parameter-Efficient Fine-Tuning for Volumetric Organ Segmentationcited by 17
  25. 2022Radiology Text Analysis System (RadText): Architecture and Evaluationcited by 5

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Cited by year (2026 to 14 Oct)

Citing papers per year: 2026: 2.

2 papers.

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Close in wording, no citation either way

  1. 2023Vision-Language Modelling For Radiological Imaging and Reports In The Low Data Regime
  2. 2025More performant and scalable: Rethinking contrastive vision-language pre-training of radiology in the LLM era
  3. 2025Comprehensive language-image pre-training for 3D medical image understanding
  4. 2025Large-scale and Fine-grained Vision-language Pre-training for Enhanced CT Image Understanding
  5. 2025Evaluating Vision Language Models (VLMs) for Radiology: A Comprehensive Analysis
  6. 2026Learning to Read Where to Look: Disease-Aware Vision-Language Pretraining for 3D CT
  7. 2024DeViDe: Faceted medical knowledge for improved medical vision-language pre-training
  8. 2023Multi-modal Pre-training for Medical Vision-language Understanding and Generation: An Empirical Study with A New Benchmark