Modeling Challenging Patient Interactions: LLMs for Medical Communication Training
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Abstract (arXiv)
Effective patient communication is pivotal in healthcare, yet traditional medical training often lacks exposure to diverse, challenging interpersonal dynamics. To bridge this gap, this study proposes the use of Large Language Models (LLMs) to simulate authentic patient communication styles, specifically the "accuser" and "rationalizer" personas derived from the Satir model, while also ensuring multilingual applicability to accommodate diverse cultural contexts and enhance accessibility for medical professionals. Leveraging advanced prompt engineering, including behavioral prompts, author's notes, and stubbornness mechanisms, we developed virtual patients (VPs) that embody nuanced emotional and conversational traits. Medical professionals evaluated these VPs, rating their authenticity (accuser: 3.8 ± 1.0; rationalizer: 3.7 ± 0.8 on a 5-point Likert scale (from one to five)) and correctly identifying their styles. Emotion analysis revealed distinct profiles: the accuser exhibited pain, anger, and distress, while the rationalizer displayed contemplation and calmness, aligning with predefined, detailed patient description including medical history. Sentiment scores (on a scale from zero to nine) further validated these differences in the communication styles, with the accuser adopting negative (3.1 ± 0.6) and the rationalizer more neutral (4.0 ± 0.4) tone. These results underscore LLMs' capability to replicate complex communication styles, offering transformative potential for medical education. This approach equips trainees to navigate challenging clinical scenarios by providing realistic, adaptable patient interactions, enhancing empathy and diagnostic acumen. Our findings advocate for AI-driven tools as scalable, cost-effective solutions to cultivate nuanced communication skills, setting a foundation for future innovations in healthcare training.
Key facts. Cited by 7 papers in the map (data through 14 Oct 2026). Builds on 13 of its 38 references that are in the map. First posted on arXiv 28 Mar 2025.
Builds on
13 of 38 references.
References · 13
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- 2019Language Models as Knowledge Bases?cited by 1,936
- 2020GoEmotions: A Dataset of Fine-Grained Emotionscited by 486
- 2023Better Zero-Shot Reasoning with Role-Play Promptingcited by 223
- 2024Roleplay-doh: Enabling Domain-Experts to Create LLM-simulated Patients via Eliciting and Adhering to Principlescited by 73
- 2024Interactive Agents: Simulating Counselor-Client Psychological Counseling via Role-Playing LLM-to-LLM Interactionscited by 43
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- 2024Leveraging Large Language Model as Simulated Patients for Clinical Educationcited by 21
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Built on by
Citing papers per year: 2025: 4; 2026: 3.
7 papers.
- 2025RECAP: Transparent Inference-Time Emotion Alignment for Medical Dialogue Systemscited by 3
- 2025Human or LLM as Standardized Patients? A Comparative Study for Medical Educationcited by 2
- 2025When Avatars Have Personality: Effects on Engagement and Communication in Immersive Medical Trainingcited by 0
- 2025An Agentic AI Framework for Training General Practitioner Student Skillscited by 0
- 2026Safeguarding Privacy: Privacy-Preserving Detection of Mind Wandering and Disengagement Using Federated Learning in Online Educationcited by 0
- 2026Beyond Prompt: Fine-grained Simulation of Cognitively Impaired Standardized Patients via Stochastic Steeringcited by 0
- 2026From Pattern Recognizers to Personalized Companions: A Survey of Large Language Models in Mental Healthcited by 0
- 2026From Pattern Recognizers to Personalized Companions: A Survey of Large Language Models in Mental Health21 Sep 2026
- 2026Beyond Prompt: Fine-grained Simulation of Cognitively Impaired Standardized Patients via Stochastic Steering14 Apr 2026
- 2026Safeguarding Privacy: Privacy-Preserving Detection of Mind Wandering and Disengagement Using Federated Learning in Online Education10 Feb 2026
- 2025An Agentic AI Framework for Training General Practitioner Student Skills20 Dec 2025
- 2025Human or LLM as Standardized Patients? A Comparative Study for Medical Education12 Nov 2025
- 2025When Avatars Have Personality: Effects on Engagement and Communication in Immersive Medical Training17 Sep 2025
- 2025RECAP: Transparent Inference-Time Emotion Alignment for Medical Dialogue Systems12 Sep 2025