A Survey on Memory-Efficient Transformer-Based Model Training in AI for Science
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Abstract (arXiv)
Scientific research faces high costs and inefficiencies with traditional methods, but the rise of deep learning and large language models (LLMs) offers innovative solutions. This survey reviews transformer-based LLM applications across scientific fields such as biology, medicine, chemistry, and meteorology, underscoring their role in advancing research. However, the continuous expansion of model size has led to significant memory demands, hindering further development and application of LLMs for science. This survey systematically reviews and categorizes memory-efficient pre-training techniques for large-scale transformers, including algorithm-level, system-level, and hardware-software co-optimization. Using AlphaFold 2 as an example, we demonstrate how tailored memory optimization methods can reduce storage needs while preserving prediction accuracy. By bridging model efficiency and scientific application needs, we hope to provide insights for scalable and cost-effective LLM training in AI for science.
Key facts. Cited by 3 papers in the map (data through 7 Oct 2026). Builds on 69 of its 112 references that are in the map. First posted on arXiv 21 Jan 2025.
Builds on
69 of 112 references.
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Citing papers per year: 2025: 1; 2026: 2.
3 papers.
- 2025Preconditioned Norms: A Unified Framework for Steepest Descent, Quasi-Newton and Adaptive Methodscited by 9
- 2026GRASS: Gradient-based Adaptive Layer-wise Importance Sampling for Memory-efficient Large Language Model Fine-tuningcited by 1
- 2026Memory-Efficient Activation Checkpointing with Sliding Window and Hirschberg's Algorithm for 0/1 Knapsack Solving in PyTorchcited by 0
- 2026Memory-Efficient Activation Checkpointing with Sliding Window and Hirschberg's Algorithm for 0/1 Knapsack Solving in PyTorch9 Aug 2026
- 2026GRASS: Gradient-based Adaptive Layer-wise Importance Sampling for Memory-efficient Large Language Model Fine-tuning9 Apr 2026
- 2025Preconditioned Norms: A Unified Framework for Steepest Descent, Quasi-Newton and Adaptive Methods12 Oct 2025