Unified Cross-Modal Medical Image Synthesis with Hierarchical Mixture of Product-of-Experts
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Abstract (arXiv)
We propose a deep mixture of multimodal hierarchical variational auto-encoders called MMHVAE that synthesizes missing images from observed images in different modalities. MMHVAE's design focuses on tackling four challenges: (i) creating a complex latent representation of multimodal data to generate high-resolution images; (ii) encouraging the variational distributions to estimate the missing information needed for cross-modal image synthesis; (iii) learning to fuse multimodal information in the context of missing data; (iv) leveraging dataset-level information to handle incomplete data sets at training time. Extensive experiments are performed on the challenging problem of pre-operative brain multi-parametric magnetic resonance and intra-operative ultrasound imaging.
Key facts. Cited by 8 papers in the map (data through 7 Oct 2026). Builds on 33 of its 56 references that are in the map. First posted on arXiv 25 Oct 2024.
Builds on
33 of 56 references.
References · 33
- 2018The Unreasonable Effectiveness of Deep Features as a Perceptual Metriccited by 11,029
- 2018MobileNetV2: Inverted Residuals and Linear Bottleneckscited by 4,773
- 2017Squeeze-and-Excitation Networkscited by 4,763
- 2016Image-to-Image Translation with Conditional Adversarial Networkscited by 4,510
- 2019Semantic Image Synthesis with Spatially-Adaptive Normalizationcited by 1,295
- 2020NVAE: A Deep Hierarchical Variational Autoencodercited by 635
- 2018Identifying the Best Machine Learning Algorithms for Brain Tumor Segmentation, Progression Assessment, and Overall Survival Prediction in the BRATS Challengecited by 508
- 2016Ladder Variational Autoencoderscited by 315
- 2021SynthSeg: Segmentation of brain MRI scans of any contrast and resolution without retrainingcited by 235
- 2022BBDM: Image-to-image Translation with Brownian Bridge Diffusion Modelscited by 222
- 2018Multimodal Generative Models for Scalable Weakly-Supervised Learningcited by 200
- 2019Variational Mixture-of-Experts Autoencoders for Multi-Modal Deep Generative Modelscited by 177
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- 2021ResViT: Residual vision transformers for multi-modal medical image synthesiscited by 177
- 2023On Memorization in Diffusion Modelscited by 122
- 2019BIVA: A Very Deep Hierarchy of Latent Variables for Generative Modelingcited by 109
- 2016HeMIS: Hetero-Modal Image Segmentationcited by 102
- 2019Missing MRI Pulse Sequence Synthesis using Multi-Modal Generative Adversarial Networkcited by 98
- 2015Hierarchical Variational Modelscited by 89
- 2020Hi-Net: Hybrid-fusion Network for Multi-modal MR Image Synthesiscited by 86
- 2021Generalized Multimodal ELBOcited by 86
- 2019Disentangled Representation Learning in Cardiac Image Analysiscited by 69
- 2019Hetero-Modal Variational Encoder-Decoder for Joint Modality Completion and Segmentationcited by 68
- 2023CoLa-Diff: Conditional Latent Diffusion Model for Multi-Modal MRI Synthesiscited by 64
- 2022CrossMoDA 2021 challenge: Benchmark of Cross-Modality Domain Adaptation techniques for Vestibular Schwannoma and Cochlea Segmentationcited by 58
- 2019DiamondGAN: Unified Multi-Modal Generative Adversarial Networks for MRI Sequences Synthesiscited by 36
- 2019CollaGAN : Collaborative GAN for Missing Image Data Imputationcited by 33
- 2022A Novel Unified Conditional Score-based Generative Framework for Multi-modal Medical Image Completioncited by 23
- 2020Self-Supervised Ultrasound to MRI Fetal Brain Image Synthesiscited by 18
- 2020Learning joint segmentation of tissues and brain lesions from task-specific hetero-modal domain-shifted datasetscited by 15
- 2023Unified Brain MR-Ultrasound Synthesis using Multi-Modal Hierarchical Representationscited by 13
- 2018PIMMS: Permutation Invariant Multi-Modal Segmentationcited by 9
- 2024Patient-Specific Real-Time Segmentation in Trackerless Brain Ultrasoundcited by 7
- 2022RESECT-SEG: Open access annotations of intra-operative brain tumor ultrasound imagescited by 6
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Citing papers per year: 2025: 3; 2026: 5.
8 papers.
- 2025Virtual Full-stack Scanning of Brain MRI via Imputing Any Quantised Codecited by 4
- 2025A 3D Cross-modal Keypoint Descriptor for MR-US Matching and Registrationcited by 3
- 2025The Brain Resection Multimodal Image Registration (ReMIND2Reg) 2025 Challengecited by 3
- 2026A Systematic Benchmark of Intraoperative Ultrasound-to-MR Synthesis for Brain Tumour Surgerycited by 2
- 2026Data-driven registration and modeling of brain deformation for image-guided neurosurgerycited by 0
- 2026MeDUET: Disentangled Unified Pretraining for 3D Medical Image Synthesis and Analysiscited by 0
- 2026What neurosurgeons need to see: synthetic intra-operative MRI from ultrasound for brain-shift compensation in brain tumour surgerycited by 0
- 2026Posterior Samplings are Missing Modalities Generators for Medical Image Translationcited by 0
- 2026Posterior Samplings are Missing Modalities Generators for Medical Image Translation21 Jul 2026
- 2026What neurosurgeons need to see: synthetic intra-operative MRI from ultrasound for brain-shift compensation in brain tumour surgery3 Jun 2026
- 2026A Systematic Benchmark of Intraoperative Ultrasound-to-MR Synthesis for Brain Tumour Surgery30 May 2026
- 2026MeDUET: Disentangled Unified Pretraining for 3D Medical Image Synthesis and Analysis19 Feb 2026
- 2026Data-driven registration and modeling of brain deformation for image-guided neurosurgery9 Feb 2026
- 2025The Brain Resection Multimodal Image Registration (ReMIND2Reg) 2025 Challenge13 Aug 2025
- 2025A 3D Cross-modal Keypoint Descriptor for MR-US Matching and Registration24 Jul 2025
- 2025Virtual Full-stack Scanning of Brain MRI via Imputing Any Quantised Code30 Jan 2025