RiTeK: A Dataset for Large Language Models Complex Reasoning over Textual Knowledge Graphs in Medicine
On the map: LLM reasoning → Clinical and biomedical applications
Abstract (arXiv)
Answering complex real-world questions in the medical domain often requires accurate retrieval from medical Textual Knowledge Graphs (medical TKGs), as the relational path information from TKGs could enhance the inference ability of Large Language Models (LLMs). However, the main bottlenecks lie in the scarcity of existing medical TKGs, the limited expressiveness of their topological structures, and the lack of comprehensive evaluations of current retrievers for medical TKGs. To address these challenges, we first develop a Dataset1 for LLMs Complex Reasoning over medical Textual Knowledge Graphs (RiTeK), covering a broad range of topological structures. Specifically, we synthesize realistic user queries integrating diverse topological structures, relational information, and complex textual descriptions. We conduct a rigorous medical expert evaluation process to assess and validate the quality of our synthesized queries. RiTeK also serves as a comprehensive benchmark dataset for evaluating the capabilities of retrieval systems built upon LLMs. By assessing 11 representative retrievers on this benchmark, we observe that existing methods struggle to perform well, revealing notable limitations in current LLM-driven retrieval approaches. These findings highlight the pressing need for more effective retrieval systems tailored for semi-structured data in the medical domain.
Key facts. Cited by 6 papers in the map (data through 7 Oct 2026). Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning. Builds on 18 of its 35 references that are in the map. First posted on arXiv 17 Oct 2024.
Builds on
18 of 35 references.
References · 18
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6 more
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Built on by
Citing papers per year: 2024: 1; 2025: 2; 2026: 3.
6 papers.
- 2025A Survey of Graph Retrieval-Augmented Generation for Customized Large Language Modelscited by 85
- 2024RARE: Retrieval-Augmented Reasoning Enhancement for Large Language Modelscited by 24
- 2026EvolveRouter: Co-Evolving Routing and Prompt for Multi-Agent Question Answeringcited by 13
- 2025AutoGraph-R1: End-to-End Reinforcement Learning for Knowledge Graph Constructioncited by 6
- 2026GLEN-Bench: A Graph-Language based Benchmark for Nutritional Healthcited by 6
- 2026In-Context Optimization for Retrieval-Augmented Generation: A Gradient-Descent Perspectivecited by 0
- 2026In-Context Optimization for Retrieval-Augmented Generation: A Gradient-Descent Perspective25 May 2026
- 2026EvolveRouter: Co-Evolving Routing and Prompt for Multi-Agent Question Answering6 Apr 2026
- 2026GLEN-Bench: A Graph-Language based Benchmark for Nutritional Health26 Jan 2026
- 2025AutoGraph-R1: End-to-End Reinforcement Learning for Knowledge Graph Construction17 Oct 2025
- 2025A Survey of Graph Retrieval-Augmented Generation for Customized Large Language Models21 Jan 2025
- 2024RARE: Retrieval-Augmented Reasoning Enhancement for Large Language Models3 Dec 2024
Similar, not cited
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- 2026ReGraM: Region-First Knowledge Graph Reasoning for Medical Question Answering
- 2024MedG-KRP: Medical Graph Knowledge Representation Probing
- 2023HyKGE: A Hypothesis Knowledge Graph Enhanced Framework for Accurate and Reliable Medical LLMs Responses
- 2025Agentic Medical Knowledge Graphs Enhance Medical Question Answering: Bridging the Gap Between LLMs and Evolving Medical Knowledge
- 2025MKG-Rank: Enhancing Large Language Models with Knowledge Graph for Multilingual Medical Question Answering
- 2024Reasoning-Enhanced Healthcare Predictions with Knowledge Graph Community Retrieval
- 2025MedKGent: A Large Language Model Agent Framework for Constructing Temporally Evolving Medical Knowledge Graph
- 2023Leveraging Medical Knowledge Graphs Into Large Language Models for Diagnosis Prediction: Design and Application Study