Time Matters: Examine Temporal Effects on Biomedical Language Models
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Abstract (arXiv)
Time roots in applying language models for biomedical applications: models are trained on historical data and will be deployed for new or future data, which may vary from training data. While increasing biomedical tasks have employed state-of-the-art language models, there are very few studies have examined temporal effects on biomedical models when data usually shifts across development and deployment. This study fills the gap by statistically probing relations between language model performance and data shifts across three biomedical tasks. We deploy diverse metrics to evaluate model performance, distance methods to measure data drifts, and statistical methods to quantify temporal effects on biomedical language models. Our study shows that time matters for deploying biomedical language models, while the degree of performance degradation varies by biomedical tasks and statistical quantification approaches. We believe this study can establish a solid benchmark to evaluate and assess temporal effects on deploying biomedical language models.
Key facts. Cited by 7 papers in the map (data through 7 Oct 2026). Builds on 17 of its 43 references that are in the map. First posted on arXiv 24 Jul 2024.
Builds on
17 of 43 references.
References · 17
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5 more
- 2020BioALBERT: A Simple and Effective Pre-trained Language Model for Biomedical Named Entity Recognitioncited by 19
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Built on by
Citing papers per year: 2024: 2; 2025: 3; 2026: 2.
7 papers.
- 2025Protein Large Language Models: A Comprehensive Surveycited by 18
- 2025Examining and Adapting Time for Multilingual Classification via Mixture of Temporal Expertscited by 9
- 2024Predicting 30-Day Hospital Readmission in Medicare Patients: Insights from an LSTM Deep Learning Modelcited by 8
- 2026Safeguarding LLM Agents against Long-Horizon Threats via Shadow Memorycited by 6
- 2024Examining Imbalance Effects on Performance and Demographic Fairness of Clinical Language Modelscited by 4
- 2025Affective-ROPTester: Capability and Bias Analysis of LLMs in Predicting Retinopathy of Prematuritycited by 3
- 2026Knowledge-driven Augmentation and Retrieval for Integrative Temporal Adaptationcited by 1
- 2026Safeguarding LLM Agents against Long-Horizon Threats via Shadow Memory4 May 2026
- 2026Knowledge-driven Augmentation and Retrieval for Integrative Temporal Adaptation23 Apr 2026
- 2025Affective-ROPTester: Capability and Bias Analysis of LLMs in Predicting Retinopathy of Prematurity8 Jul 2025
- 2025Protein Large Language Models: A Comprehensive Survey21 Feb 2025
- 2025Examining and Adapting Time for Multilingual Classification via Mixture of Temporal Experts12 Feb 2025
- 2024Examining Imbalance Effects on Performance and Demographic Fairness of Clinical Language Models23 Dec 2024
- 2024Predicting 30-Day Hospital Readmission in Medicare Patients: Insights from an LSTM Deep Learning Model23 Oct 2024