Causality extraction from medical text using Large Language Models (LLMs)
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Abstract (arXiv)
This study explores the potential of natural language models, including large language models, to extract causal relations from medical texts, specifically from Clinical Practice Guidelines (CPGs). The outcomes causality extraction from Clinical Practice Guidelines for gestational diabetes are presented, marking a first in the field. We report on a set of experiments using variants of BERT (BioBERT, DistilBERT, and BERT) and using Large Language Models (LLMs), namely GPT-4 and LLAMA2. Our experiments show that BioBERT performed better than other models, including the Large Language Models, with an average F1-score of 0.72. GPT-4 and LLAMA2 results show similar performance but less consistency. We also release the code and an annotated a corpus of causal statements within the Clinical Practice Guidelines for gestational diabetes.
Key facts. Cited by 7 papers in the map (data through 7 Oct 2026). Builds on 19 of its 73 references that are in the map. First posted on arXiv 13 Jul 2024.
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19 of 73 references.
References · 19
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7 more
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Citing papers per year: 2024: 2; 2025: 4; 2026: 1.
7 papers.
- 2025A Survey on Enhancing Causal Reasoning Ability of Large Language Modelscited by 8
- 2024Counterfactual Causal Inference in Natural Language with Large Language Modelscited by 7
- 2024A Survey of Event Causality Identification: Taxonomy, Challenges, Assessment, and Prospectscited by 6
- 2025Refine Medical Diagnosis Using Generation Augmented Retrieval and Clinical Practice Guidelinescited by 1
- 2026Benchmarking LLMs for Pairwise Causal Discovery in Biomedical and Multi-Domain Contextscited by 1
- 2025Quantifying Symptom Causality in Clinical Decision Making: An Exploration Using CausaLMcited by 0
- 2025Zero-Shot Event Causality Identification via Multi-source Evidence Fuzzy Aggregation with Large Language Modelscited by 0
- 2026Benchmarking LLMs for Pairwise Causal Discovery in Biomedical and Multi-Domain Contexts21 Jan 2026
- 2025Refine Medical Diagnosis Using Generation Augmented Retrieval and Clinical Practice Guidelines22 Jun 2025
- 2025Zero-Shot Event Causality Identification via Multi-source Evidence Fuzzy Aggregation with Large Language Models6 Jun 2025
- 2025Quantifying Symptom Causality in Clinical Decision Making: An Exploration Using CausaLM25 Mar 2025
- 2025A Survey on Enhancing Causal Reasoning Ability of Large Language Models12 Mar 2025
- 2024A Survey of Event Causality Identification: Taxonomy, Challenges, Assessment, and Prospects15 Nov 2024
- 2024Counterfactual Causal Inference in Natural Language with Large Language Models8 Oct 2024