Knowledge-Infused LLM-Powered Conversational Health Agent: A Case Study for Diabetes Patients
On the map: LLM agents and tool use → Medical and scientific domain agents
Abstract (arXiv)
Effective diabetes management is crucial for maintaining health in diabetic patients. Large Language Models (LLMs) have opened new avenues for diabetes management, facilitating their efficacy. However, current LLM-based approaches are limited by their dependence on general sources and lack of integration with domain-specific knowledge, leading to inaccurate responses. In this paper, we propose a knowledge-infused LLM-powered conversational health agent (CHA) for diabetic patients. We customize and leverage the open-source openCHA framework, enhancing our CHA with external knowledge and analytical capabilities. This integration involves two key components: 1) incorporating the American Diabetes Association dietary guidelines and the Nutritionix information and 2) deploying analytical tools that enable nutritional intake calculation and comparison with the guidelines. We compare the proposed CHA with GPT4. Our evaluation includes 100 diabetes-related questions on daily meal choices and assessing the potential risks associated with the suggested diet. Our findings show that the proposed agent demonstrates superior performance in generating responses to manage essential nutrients.
Key facts. Cited by 9 papers in the map (data through 7 Oct 2026). Placed in Medical and scientific domain agents, one of 16 directions in LLM agents and tool use. Builds on 4 of its 26 references that are in the map. First posted on arXiv 15 Feb 2024.
Builds on
4 of 26 references.
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Other references · 3
- 2021LoRA: Low-Rank Adaptation of Large Language Modelscited by 14,084
- 2023Tree of Thoughts: Deliberate Problem Solving with Large Language Modelscited by 3,155
- 2024Personal LLM Agents: Insights and Survey about the Capability, Efficiency and Securitycited by 257
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Citing papers per year: 2024: 4; 2025: 3; 2026: 2.
9 papers.
- 2024Two Tales of Persona in LLMs: A Survey of Role-Playing and Personalizationcited by 203
- 2025Advancing and Benchmarking Personalized Tool Invocation for LLMscited by 7
- 2024Graph-Augmented LLMs for Personalized Health Insights: A Case Study in Sleep Analysiscited by 3
- 2024Copiloting Diagnosis of Autism in Real Clinical Scenarios via LLMscited by 3
- 2024Accuracy and Consistency of LLMs in the Registered Dietitian Exam: The Impact of Prompt Engineering and Knowledge Retrievalcited by 2
- 2025SePA: A Search-enhanced Predictive Agent for Personalized Health Coachingcited by 1
- 2025Personalized Causal Graph Reasoning for LLMs: An Implementation for Dietary Recommendationscited by 0
- 2026If Only My CGM Could Speak: A Privacy-Preserving Agent for Question Answering over Continuous Glucose Datacited by 0
- 2026Investigating the Ability of Large Language Models to Analyze Recipes for Diabetescited by 0
- 2026Investigating the Ability of Large Language Models to Analyze Recipes for Diabetes3 Sep 2026
- 2026If Only My CGM Could Speak: A Privacy-Preserving Agent for Question Answering over Continuous Glucose Data18 Apr 2026
- 2025SePA: A Search-enhanced Predictive Agent for Personalized Health Coaching5 Sep 2025
- 2025Advancing and Benchmarking Personalized Tool Invocation for LLMs7 May 2025
- 2025Personalized Causal Graph Reasoning for LLMs: An Implementation for Dietary Recommendations28 Feb 2025
- 2024Copiloting Diagnosis of Autism in Real Clinical Scenarios via LLMs8 Oct 2024
- 2024Accuracy and Consistency of LLMs in the Registered Dietitian Exam: The Impact of Prompt Engineering and Knowledge Retrieval6 Aug 2024
- 2024Graph-Augmented LLMs for Personalized Health Insights: A Case Study in Sleep Analysis24 Jun 2024
- 2024Two Tales of Persona in LLMs: A Survey of Role-Playing and Personalization3 Jun 2024
Similar, not cited
Close in wording, no citation either way
- 2025Advice for Diabetes Self-Management by ChatGPT Models: Challenges and Recommendations
- 2025A Survey of LLM-based Agents in Medicine: How far are we from Baymax?
- 2025CGM-Led Multimodal Tracking with Chatbot Support: An Autoethnography in Sub-Health ↗
- 2026ClinQueryAgent: A Conversational Agent for Population Health Management
- 2026HealthLoopQA: A Context-Aware Question Answering Benchmark for Interpreting Wearable Monitoring Data in Diabetes Care
- 2023Large Language Models Illuminate a Progressive Pathway to Artificial Healthcare Assistant: A Review
- 2025An LLM-Powered Agent for Physiological Data Analysis: A Case Study on PPG-based Heart Rate Estimation
- 2026A knowledge-guided agentic framework for mitigating patient-context ambiguity in health queries