Medical Vision Language Pretraining: A survey
On the map: Multimodal LLMs / vision-language models → Medical vision-language models
Abstract (arXiv)
Medical Vision Language Pretraining (VLP) has recently emerged as a promising solution to the scarcity of labeled data in the medical domain. By leveraging paired/unpaired vision and text datasets through self-supervised learning, models can be trained to acquire vast knowledge and learn robust feature representations. Such pretrained models have the potential to enhance multiple downstream medical tasks simultaneously, reducing the dependency on labeled data. However, despite recent progress and its potential, there is no such comprehensive survey paper that has explored the various aspects and advancements in medical VLP. In this paper, we specifically review existing works through the lens of different pretraining objectives, architectures, downstream evaluation tasks, and datasets utilized for pretraining and downstream tasks. Subsequently, we delve into current challenges in medical VLP, discussing existing and potential solutions, and conclude by highlighting future directions. To the best of our knowledge, this is the first survey focused on medical VLP.
Key facts. Cited by 24 papers in the map (data through 7 Oct 2026). Placed in Medical vision-language models, one of 16 directions in Multimodal LLMs / vision-language models. Builds on 114 of its 161 references that are in the map. First posted on arXiv 11 Dec 2023.
Builds on
114 of 161 references.
Closest ancestors · 19
Same direction, newest first
- 2023CXR-CLIP: Toward Large Scale Chest X-ray Language-Image Pre-training20 Oct
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- 2023Enhancing Representation in Radiography-Reports Foundation Model: A Granular Alignment Algorithm Using Masked Contrastive Learning12 Sep
- 2023A Foundation Language-Image Model of the Retina (FLAIR): Encoding Expert Knowledge in Text Supervision15 Aug
- 2023Exploring Transfer Learning in Medical Image Segmentation using Vision-Language Models15 Aug
- 2023M-FLAG: Medical Vision-Language Pre-training with Frozen Language Models and Latent Space Geometry Optimization17 Jul
- 2023Knowledge Boosting: Rethinking Medical Contrastive Vision-Language Pre-Training14 Jul
- 2023Multi-modal Pre-training for Medical Vision-language Understanding and Generation: An Empirical Study with A New Benchmark10 Jun
- 2023Generative Text-Guided 3D Vision-Language Pretraining for Unified Medical Image Segmentation7 Jun
- 2023LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day1 Jun
- 2023BiomedGPT: A Generalist Vision-Language Foundation Model for Diverse Biomedical Tasks26 May
7 more
- 2023MedBLIP: Bootstrapping Language-Image Pre-training from 3D Medical Images and Texts18 May
- 2023Multi-task Paired Masking with Alignment Modeling for Medical Vision-Language Pre-training13 May
- 2023Vision-Language Modelling For Radiological Imaging and Reports In The Low Data Regime30 Mar
- 2022Self-supervised vision-language pretraining for Medical visual question answering24 Nov
- 2022RoentGen: Vision-Language Foundation Model for Chest X-ray Generation23 Nov
- 2022Medical Image Understanding with Pretrained Vision Language Models: A Comprehensive Study30 Sep
- 2021Multi-modal Understanding and Generation for Medical Images and Text via Vision-Language Pre-Training24 May
Other references · 95
- 2017Attention Is All You Needcited by 59,932
- 2015Deep Residual Learning for Image Recognitioncited by 51,809
- 2018BERT: Pre-training of Deep Bidirectional Transformers for Language Understandingcited by 40,204
- 2021Learning Transferable Visual Models From Natural Language Supervisioncited by 33,456
- 2020An Image is Worth 16x16 Words: Transformers for Image Recognition at Scalecited by 29,915
- 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,604
- 2021Swin Transformer: Hierarchical Vision Transformer using Shifted Windowscited by 12,082
- 2020A Simple Framework for Contrastive Learning of Visual Representationscited by 11,979
- 2021Masked Autoencoders Are Scalable Vision Learnerscited by 7,339
- 2021Scaling Up Visual and Vision-Language Representation Learning With Noisy Text Supervisioncited by 3,848
- 2019ViLBERT: Pretraining Task-Agnostic Visiolinguistic Representations for Vision-and-Language Taskscited by 2,219
- 2022Visual Prompt Tuningcited by 1,674
38 more
- 2021LAION-400M: Open Dataset of CLIP-Filtered 400 Million Image-Text Pairscited by 1,544
- 2015Show, Attend and Tell: Neural Image Caption Generation with Visual Attentioncited by 1,421
- 2019CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparisoncited by 1,410
- 2019VisualBERT: A Simple and Performant Baseline for Vision and Languagecited by 1,291
- 2021Grounded Language-Image Pre-trainingcited by 1,147
- 2020Domain-Specific Language Model Pretraining for Biomedical Natural Language Processingcited by 996
- 2019Publicly Available Clinical BERT Embeddingscited by 995
- 2017ChestX-ray8: Hospital-scale Chest X-ray Database and Benchmarks on Weakly-Supervised Classification and Localization of Common Thorax Diseasescited by 969
- 2021MedMNIST v2 -- A large-scale lightweight benchmark for 2D and 3D biomedical image classificationcited by 682
- 2019Unified Language Model Pre-training for Natural Language Understanding and Generationcited by 668
- 2020Contrastive Learning of Medical Visual Representations from Paired Images and Textcited by 636
- 2022MedCLIP: Contrastive Learning from Unpaired Medical Images and Textcited by 564
- 2019End-to-End Learning of Visual Representations from Uncurated Instructional Videoscited by 506
- 2023BiomedCLIP: a multimodal biomedical foundation model pretrained from fifteen million scientific image-text pairscited by 506
- 2020PathVQA: 30000+ Questions for Medical Visual Question Answeringcited by 467
- 2021SLAKE: A Semantically-Labeled Knowledge-Enhanced Dataset for Medical Visual Question Answeringcited by 444
- 2018Rotation Equivariant CNNs for Digital Pathologycited by 420
- 2021Supervision Exists Everywhere: A Data Efficient Contrastive Language-Image Pre-training Paradigmcited by 405
- 2022Making the Most of Text Semantics to Improve Biomedical Vision--Language Processingcited by 336
- 2020CheXbert: Combining Automatic Labelers and Expert Annotations for Accurate Radiology Report Labeling Using BERTcited by 329
- 2021RadGraph: Extracting Clinical Entities and Relations from Radiology Reportscited by 310
- 2019PadChest: A large chest x-ray image dataset with multi-label annotated reportscited by 308
- 2021TransBTS: Multimodal Brain Tumor Segmentation Using Transformercited by 265
- 2020COVID-Net: A Tailored Deep Convolutional Neural Network Design for Detection of COVID-19 Cases from Chest X-Ray Imagescited by 264
- 2020VinDr-CXR: An open dataset of chest X-rays with radiologist's annotationscited by 236
- 2023Improving CLIP Training with Language Rewritescited by 216
- 2023PMC-CLIP: Contrastive Language-Image Pre-training using Biomedical Documentscited by 212
- 2023Learning to Exploit Temporal Structure for Biomedical Vision-Language Processingcited by 210
- 2016Validation, comparison, and combination of algorithms for automatic detection of pulmonary nodules in computed tomography images: the LUNA16 challengecited by 198
- 2016Skin Lesion Analysis toward Melanoma Detection: A Challenge at the International Symposium on Biomedical Imaging (ISBI) 2016, hosted by the International Skin Imaging Collaboration (ISIC)cited by 197
- 2023Quilt-1M: One Million Image-Text Pairs for Histopathologycited by 192
- 2021ResViT: Residual vision transformers for multi-modal medical image synthesiscited by 177
- 2023Towards Generalist Foundation Model for Radiology by Leveraging Web-scale 2D&3D Medical Datacited by 176
- 2022Multi-Granularity Cross-modal Alignment for Generalized Medical Visual Representation Learningcited by 159
- 2023MedKLIP: Medical Knowledge Enhanced Language-Image Pre-Training in Radiologycited by 149
- 2020Improving Factual Completeness and Consistency of Image-to-Text Radiology Report Generationcited by 139
- 2023Visual Language Pretrained Multiple Instance Zero-Shot Transfer for Histopathology Imagescited by 132
- 2020Intriguing Properties of Contrastive Lossescited by 129
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- 2025Hallucination-Aware Multimodal Benchmark for Gastrointestinal Image Analysis with Large Vision-Language Models11 May 2025
- 2024SJTU:Spatial judgments in multimodal models towards unified segmentation through coordinate detection3 Dec 2024
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- 2024TuneVLSeg: Prompt Tuning Benchmark for Vision-Language Segmentation Models7 Oct 2024
- 2024PromptSmooth: Certifying Robustness of Medical Vision-Language Models via Prompt Learning29 Aug 2024
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- 2025Brain Imaging Foundation Models, Are We There Yet? A Systematic Review of Foundation Models for Brain Imaging and Biomedical Research16 Jun 2025
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- 2025CLIP-KOA: Enhancing Knee Osteoarthritis Diagnosis with Multi-Modal Learning and Symmetry-Aware Loss Functions28 Apr 2025
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- 2024Pre-training on High Definition X-ray Images: An Experimental Study27 Apr 2024
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- 2023Masked Contrastive Reconstruction for Cross-modal Medical Image-Report Retrieval26 Dec 2023
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