Ophtha-LLaMA2: A Large Language Model for Ophthalmology
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Abstract (arXiv)
In recent years, pre-trained large language models (LLMs) have achieved tremendous success in the field of Natural Language Processing (NLP). Prior studies have primarily focused on general and generic domains, with relatively less research on specialized LLMs in the medical field. The specialization and high accuracy requirements for diagnosis in the medical field, as well as the challenges in collecting large-scale data, have constrained the application and development of LLMs in medical scenarios. In the field of ophthalmology, clinical diagnosis mainly relies on doctors' interpretation of reports and making diagnostic decisions. In order to take advantage of LLMs to provide decision support for doctors, we collected three modalities of ophthalmic report data and fine-tuned the LLaMA2 model, successfully constructing an LLM termed the "Ophtha-LLaMA2" specifically tailored for ophthalmic disease diagnosis. Inference test results show that even with a smaller fine-tuning dataset, Ophtha-LLaMA2 performs significantly better in ophthalmic diagnosis compared to other LLMs. It demonstrates that the Ophtha-LLaMA2 exhibits satisfying accuracy and efficiency in ophthalmic disease diagnosis, making it a valuable tool for ophthalmologists to provide improved diagnostic support for patients. This research provides a useful reference for the application of LLMs in the field of ophthalmology, while showcasing the immense potential and prospects in this domain.
Key facts. Cited by 9 papers in the map (data through 14 Oct 2026). Builds on 23 of its 39 references that are in the map. First posted on arXiv 8 Dec 2023.
Builds on
23 of 39 references.
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Citing papers per year: 2024: 6; 2025: 2; 2026: 1.
9 papers.
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- 2024Potential of Multimodal Large Language Models for Data Mining of Medical Images and Free-text Reportscited by 6
- 2025Large Language Models for Bioinformaticscited by 3
- 2026X-PCR: A Benchmark for Cross-modality Progressive Clinical Reasoning in Ophthalmic Diagnosiscited by 0
- 2026X-PCR: A Benchmark for Cross-modality Progressive Clinical Reasoning in Ophthalmic Diagnosis22 Apr 2026
- 2025Multimodal Large Language Models for Medicine: A Comprehensive Survey29 Apr 2025
- 2025Large Language Models for Bioinformatics10 Jan 2025
- 2024Opportunities and Challenges of Large Language Models for Low-Resource Languages in Humanities Research30 Nov 2024
- 2024Transcending Language Boundaries: Harnessing LLMs for Low-Resource Language Translation18 Nov 2024
- 2024Large Language Models for Manufacturing28 Oct 2024
- 2024Potential of Multimodal Large Language Models for Data Mining of Medical Images and Free-text Reports8 Jul 2024
- 2024Reasoning before Comparison: LLM-Enhanced Semantic Similarity Metrics for Domain Specialized Text Analysis17 Feb 2024
- 2024Revolutionizing Finance with LLMs: An Overview of Applications and Insights22 Jan 2024