Approaching adverse event detection utilizing transformers on clinical time-series
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Abstract (arXiv)
Patients being admitted to a hospital will most often be associated with a certain clinical development during their stay. However, there is always a risk of patients being subject to the wrong diagnosis or to a certain treatment not pertaining to the desired effect, potentially leading to adverse events. Our research aims to develop an anomaly detection system for identifying deviations from expected clinical trajectories. To address this goal we analyzed 16 months of vital sign recordings obtained from the Nordland Hospital Trust (NHT). We employed an self-supervised framework based on the STraTS transformer architecture to represent the time series data in a latent space. These representations were then subjected to various clustering techniques to explore potential patient phenotypes based on their clinical progress. While our preliminary results from this ongoing research are promising, they underscore the importance of enhancing the dataset with additional demographic information from patients. This additional data will be crucial for a more comprehensive evaluation of the method's performance.
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References · 8
- 2014Learning Phrase Representations using RNN Encoder-Decoder for Statistical Machine Translationcited by 4,057
- 2016Recurrent Neural Networks for Multivariate Time Series with Missing Valuescited by 554
- 2020Benchmarking Multivariate Time Series Classification Algorithmscited by 145
- 2021Self-Supervised Transformer for Sparse and Irregularly Sampled Multivariate Clinical Time-Seriescited by 96
- 2019Interpolation-Prediction Networks for Irregularly Sampled Time Seriescited by 89
- 2017Time Series Cluster Kernel for Learning Similarities between Multivariate Time Series with Missing Datacited by 11
- 2019Time series cluster kernels to exploit informative missingness and incomplete label informationcited by 6
- 2020Application of Deep Interpolation Network for Clustering of Physiologic Time Seriescited by 1
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