Inspire the Large Language Model by External Knowledge on BioMedical Named Entity Recognition
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Abstract (arXiv)
Large language models (LLMs) have demonstrated dominating performance in many NLP tasks, especially on generative tasks. However, they often fall short in some information extraction tasks, particularly those requiring domain-specific knowledge, such as Biomedical Named Entity Recognition (NER). In this paper, inspired by Chain-of-thought, we leverage the LLM to solve the Biomedical NER step-by-step: break down the NER task into entity span extraction and entity type determination. Additionally, for entity type determination, we inject entity knowledge to address the problem that LLM's lack of domain knowledge when predicting entity category. Experimental results show a significant improvement in our two-step BioNER approach compared to previous few-shot LLM baseline. Additionally, the incorporation of external knowledge significantly enhances entity category determination performance.
Key facts. Cited by 7 papers in the map (data through 14 Oct 2026). Builds on 13 of its 23 references that are in the map. First posted on arXiv 21 Sep 2023.
Builds on
13 of 23 references.
References · 13
- 2018BERT: Pre-training of Deep Bidirectional Transformers for Language Understandingcited by 40,399
- 2022Chain-of-Thought Prompting Elicits Reasoning in Large Language Modelscited by 12,459
- 2019BioBERT: a pre-trained biomedical language representation model for biomedical text miningcited by 1,947
- 2016End-to-end Sequence Labeling via Bi-directional LSTM-CNNs-CRFcited by 341
- 2022Unified Structure Generation for Universal Information Extractioncited by 221
- 2019A Unified MRC Framework for Named Entity Recognitioncited by 199
- 2023GPT-NER: Named Entity Recognition via Large Language Modelscited by 160
- 2023Verify-and-Edit: A Knowledge-Enhanced Chain-of-Thought Frameworkcited by 139
- 2023UniversalNER: Targeted Distillation from Large Language Models for Open Named Entity Recognitioncited by 72
- 2018Cross-type Biomedical Named Entity Recognition with Deep Multi-Task Learningcited by 28
- 2020HunFlair: An Easy-to-Use Tool for State-of-the-Art Biomedical Named Entity Recognitioncited by 26
- 2022AIONER: All-in-one scheme-based biomedical named entity recognition using deep learningcited by 13
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Citing papers per year: 2023: 1; 2024: 2; 2025: 1; 2026: 3.
7 papers.
- 2023Large Language Models for Generative Information Extraction: A Surveycited by 185
- 2024Leveraging Large Language Models for Enhanced NLP Task Performance through Knowledge Distillation and Optimized Training Strategiescited by 6
- 2024VANER: Leveraging Large Language Model for Versatile and Adaptive Biomedical Named Entity Recognitioncited by 2
- 2026FMI@SU ToxHabits: Evaluating LLMs Performance on Toxic Habit Extraction in Spanish Clinical Textscited by 1
- 2026A Guideline-Augmented Multi-Agent Framework for Schema-as-Code Biomedical Named Entity Recognitioncited by 1
- 2025Synthesized Annotation Guidelines are Knowledge-Lite Boosters for Clinical Information Extractioncited by 0
- 2026RexDrug: Reliable Multi-Drug Combination Extraction through Reasoning-Enhanced LLMscited by 0
- 2026A Guideline-Augmented Multi-Agent Framework for Schema-as-Code Biomedical Named Entity Recognition2 Oct 2026
- 2026FMI@SU ToxHabits: Evaluating LLMs Performance on Toxic Habit Extraction in Spanish Clinical Texts7 Apr 2026
- 2026RexDrug: Reliable Multi-Drug Combination Extraction through Reasoning-Enhanced LLMs9 Mar 2026
- 2025Synthesized Annotation Guidelines are Knowledge-Lite Boosters for Clinical Information Extraction1 Apr 2025
- 2024VANER: Leveraging Large Language Model for Versatile and Adaptive Biomedical Named Entity Recognition27 Apr 2024
- 2024Leveraging Large Language Models for Enhanced NLP Task Performance through Knowledge Distillation and Optimized Training Strategies14 Feb 2024
- 2023Large Language Models for Generative Information Extraction: A Survey29 Dec 2023
Similar, not cited
Close in wording, no citation either way
- 2024LLMs in Biomedicine: A study on clinical Named Entity Recognition
- 2024LLMs are not Zero-Shot Reasoners for Biomedical Information Extraction
- 2024Large Language Models Struggle in Token-Level Clinical Named Entity Recognition
- 2025An evaluation of DeepSeek Models in Biomedical Natural Language Processing
- 2025Retrieval augmented generation based dynamic prompting for few-shot biomedical named entity recognition using large language models
- 2024VerifiNER: Verification-augmented NER via Knowledge-grounded Reasoning with Large Language Models
- 2025KoGNER: A Novel Framework for Knowledge Graph Distillation on Biomedical Named Entity Recognition
- 2026Efficient and Reliable Estimation of Named Entity Linking Quality: A Case Study on GutBrainIE