mlsanityData to 7 Oct 2026

Math Agents: Computational Infrastructure, Mathematical Embedding, and Genomics

arXiv 2307.02502 ↗First posted 4 Jul 2023q-bio.OT cs.AI cs.CLcited by 15

On the map: LLM agents and tool use → Educational agents and math problem solving

Abstract (arXiv)

The advancement in generative AI could be boosted with more accessible mathematics. Beyond human-AI chat, large language models (LLMs) are emerging in programming, algorithm discovery, and theorem proving, yet their genomics application is limited. This project introduces Math Agents and mathematical embedding as fresh entries to the "Moore's Law of Mathematics", using a GPT-based workflow to convert equations from literature into LaTeX and Python formats. While many digital equation representations exist, there's a lack of automated large-scale evaluation tools. LLMs are pivotal as linguistic user interfaces, providing natural language access for human-AI chat and formal languages for large-scale AI-assisted computational infrastructure. Given the infinite formal possibility spaces, Math Agents, which interact with math, could potentially shift us from "big data" to "big math". Math, unlike the more flexible natural language, has properties subject to proof, enabling its use beyond traditional applications like high-validation math-certified icons for AI alignment aims. This project aims to use Math Agents and mathematical embeddings to address the ageing issue in information systems biology by applying multiscalar physics mathematics to disease models and genomic data. Generative AI with episodic memory could help analyse causal relations in longitudinal health records, using SIR Precision Health models. Genomic data is suggested for addressing the unsolved Alzheimer's disease problem.

Key facts. Cited by 15 papers in the map (data through 7 Oct 2026). Placed in Educational agents and math problem solving, one of 16 directions in LLM agents and tool use. Builds on 6 of its 47 references that are in the map. First posted on arXiv 4 Jul 2023.

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6 of 47 references.

References · 6

  1. 2023LeanDojo: Theorem Proving with Retrieval-Augmented Language Modelscited by 414
  2. 2023HyenaDNA: Long-Range Genomic Sequence Modeling at Single Nucleotide Resolutioncited by 187
  3. 2020The Unreasonable Effectiveness of Deep Learning in Artificial Intelligencecited by 57
  4. 2015A formal proof of the Kepler conjecturecited by 42
  5. 2023WizMap: Scalable Interactive Visualization for Exploring Large Machine Learning Embeddingscited by 28
  6. 2021Document Embedding for Scientific Articles: Efficacy of Word Embeddings vs TFIDFcited by 3

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Citing papers per year: 2023: 2; 2024: 7; 2025: 5; 2026: 1.

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  1. 2025MM-Agent: LLM as Agents for Real-world Mathematical Modeling Problem
  2. 2026From Solvers to Research: Large Language Model-Driven Formal Mathematics at the Research Frontier
  3. 2023MathChat: Converse to Tackle Challenging Math Problems with LLM Agents
  4. 2023math-PVS: A Large Language Model Framework to Map Scientific Publications to PVS Theories
  5. 2025Evaluating Frontier LLMs on PhD-Level Mathematical Reasoning: A Benchmark on a Textbook in Theoretical Computer Science about Randomized Algorithms
  6. 2024LLMs for Mathematical Modeling: Towards Bridging the Gap between Natural and Mathematical Languages
  7. 2026SciText2Eq: Assessing LLMs for Explainable Equation Generation for Scientific Creativity
  8. 2025Mathematical Computation and Reasoning Errors by Large Language Models