Misspecification-robust Sequential Neural Likelihood for Simulation-based Inference
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Abstract (arXiv)
Simulation-based inference techniques are indispensable for parameter estimation of mechanistic and simulable models with intractable likelihoods. While traditional statistical approaches like approximate Bayesian computation and Bayesian synthetic likelihood have been studied under well-specified and misspecified settings, they often suffer from inefficiencies due to wasted model simulations. Neural approaches, such as sequential neural likelihood (SNL) avoid this wastage by utilising all model simulations to train a neural surrogate for the likelihood function. However, the performance of SNL under model misspecification is unreliable and can result in overconfident posteriors centred around an inaccurate parameter estimate. In this paper, we propose a novel SNL method, which through the incorporation of additional adjustment parameters, is robust to model misspecification and capable of identifying features of the data that the model is not able to recover. We demonstrate the efficacy of our approach through several illustrative examples, where our method gives more accurate point estimates and uncertainty quantification than SNL.
Key facts. Cited by 8 papers in the map (data through 7 Oct 2026). Builds on 55 of its 112 references that are in the map. First posted on arXiv 31 Jan 2023.
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55 of 112 references.
References · 55
- 2014Adam: A Method for Stochastic Optimizationcited by 36,960
- 2019PyTorch: An Imperative Style, High-Performance Deep Learning Librarycited by 20,160
- 2016Simple and Scalable Predictive Uncertainty Estimation using Deep Ensemblescited by 3,888
- 2016A Baseline for Detecting Misclassified and Out-of-Distribution Examples in Neural Networkscited by 2,362
- 2020Sharpness-Aware Minimization for Efficiently Improving Generalizationcited by 1,404
- 2019Normalizing Flows for Probabilistic Modeling and Inferencecited by 1,315
- 2015Automatic differentiation in machine learning: a surveycited by 846
- 2021Generalized Out-of-Distribution Detection: A Surveycited by 796
- 2017Masked Autoregressive Flow for Density Estimationcited by 680
- 2019Neural Spline Flowscited by 590
- 2019The frontier of simulation-based inferencecited by 490
- 2018Pyro: Deep Universal Probabilistic Programmingcited by 379
38 more
- 2022On Neural Differential Equationscited by 264
- 2016Revisiting Classifier Two-Sample Testscited by 258
- 2020Why Normalizing Flows Fail to Detect Out-of-Distribution Datacited by 220
- 2018Sequential Neural Likelihood: Fast Likelihood-free Inference with Autoregressive Flowscited by 217
- 2019Automatic Posterior Transformation for Likelihood-Free Inferencecited by 216
- 2019Composable Effects for Flexible and Accelerated Probabilistic Programming in NumPyrocited by 187
- 2013A General Framework for Updating Belief Distributionscited by 172
- 2021Benchmarking Simulation-Based Inferencecited by 160
- 2020BayesFlow: Learning complex stochastic models with invertible neural networkscited by 139
- 2018Validating Bayesian Inference Algorithms with Simulation-Based Calibrationcited by 118
- 2020On Contrastive Learning for Likelihood-free Inferencecited by 96
- 2019Rank-normalization, folding, and localization: An improved widehatR for assessing convergence of MCMCcited by 90
- 2016Likelihood-free inference by ratio estimationcited by 80
- 2021Robust Generalised Bayesian Inference for Intractable Likelihoodscited by 53
- 2016Fast ε-free Inference of Simulation Models with Bayesian Conditional Density Estimationcited by 50
- 2022Sequential Neural Score Estimation: Likelihood-Free Inference with Conditional Score Based Diffusion Modelscited by 50
- 2021Detecting Model Misspecification in Amortized Bayesian Inference with Neural Networkscited by 48
- 2020Bayesian Workflowcited by 47
- 2022Robust Neural Posterior Estimation and Statistical Model Criticismcited by 45
- 2022Investigating the Impact of Model Misspecification in Neural Simulation-based Inferencecited by 44
- 2022Variational methods for simulation-based inferencecited by 43
- 2022Robust Bayesian Inference for Simulator-based Models via the MMD Posterior Bootstrapcited by 41
- 2019MMD-Bayes: Robust Bayesian Estimation via Maximum Mean Discrepancycited by 35
- 2021Sequential Neural Posterior and Likelihood Approximationcited by 30
- 2022Towards Reliable Simulation-Based Inference with Balanced Neural Ratio Estimationcited by 27
- 2017Visualization in Bayesian workflowcited by 25
- 2022Reliable amortized variational inference with physics-based latent distribution correctioncited by 25
- 2020Score Matched Neural Exponential Families for Likelihood-Free Inferencecited by 21
- 2020Generalized Posteriors in Approximate Bayesian Computationcited by 19
- 2021Preconditioned training of normalizing flows for variational inference in inverse problemscited by 19
- 2019Robust Approximate Bayesian Inference with Synthetic Likelihoodcited by 14
- 2020Towards constraining warm dark matter with stellar streams through neural simulation-based inferencecited by 14
- 2017ELFI: Engine for Likelihood-Free Inferencecited by 10
- 2021A Comparison of Likelihood-Free Methods With and Without Summary Statisticscited by 9
- 2022Learning Summary Statistics for Bayesian Inference with Autoencoderscited by 9
- 2018Bayesian Restricted Likelihood Methods: Conditioning on Insufficient Statistics in Bayesian Regressioncited by 6
- 2020Robust Approximate Bayesian Computation: An Adjustment Approachcited by 5
- 2021Synthetic likelihood in misspecified modelscited by 5
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Citing papers per year: 2023: 3; 2024: 4; 2025: 1.
8 papers.
- 2023Learning Robust Statistics for Simulation-based Inference under Model Misspecificationcited by 48
- 2024Neural Methods for Amortized Inferencecited by 36
- 2024Addressing Misspecification in Simulation-based Inference through Data-driven Calibrationcited by 26
- 2023Generalized Bayesian Inference for Scientific Simulators via Amortized Cost Estimationcited by 17
- 2025Does Unsupervised Domain Adaptation Improve the Robustness of Amortized Bayesian Inference? A Systematic Evaluationcited by 10
- 2024Detecting Model Misspecification in Amortized Bayesian Inference with Neural Networks: An Extended Investigationcited by 8
- 2024Preconditioned Neural Posterior Estimation for Likelihood-free Inferencecited by 6
- 2023Bayesian calibration of differentiable agent-based modelscited by 4
- 2025Does Unsupervised Domain Adaptation Improve the Robustness of Amortized Bayesian Inference? A Systematic Evaluation7 Feb 2025
- 2024Detecting Model Misspecification in Amortized Bayesian Inference with Neural Networks: An Extended Investigation5 Jun 2024
- 2024Addressing Misspecification in Simulation-based Inference through Data-driven Calibration14 May 2024
- 2024Preconditioned Neural Posterior Estimation for Likelihood-free Inference21 Apr 2024
- 2024Neural Methods for Amortized Inference18 Apr 2024
- 2023Learning Robust Statistics for Simulation-based Inference under Model Misspecification25 May 2023
- 2023Bayesian calibration of differentiable agent-based models24 May 2023
- 2023Generalized Bayesian Inference for Scientific Simulators via Amortized Cost Estimation24 May 2023