TCM-SD: A Benchmark for Probing Syndrome Differentiation via Natural Language Processing
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Abstract (arXiv)
Traditional Chinese Medicine (TCM) is a natural, safe, and effective therapy that has spread and been applied worldwide. The unique TCM diagnosis and treatment system requires a comprehensive analysis of a patient's symptoms hidden in the clinical record written in free text. Prior studies have shown that this system can be informationized and intelligentized with the aid of artificial intelligence (AI) technology, such as natural language processing (NLP). However, existing datasets are not of sufficient quality nor quantity to support the further development of data-driven AI technology in TCM. Therefore, in this paper, we focus on the core task of the TCM diagnosis and treatment system -- syndrome differentiation (SD) -- and we introduce the first public large-scale dataset for SD, called TCM-SD. Our dataset contains 54,152 real-world clinical records covering 148 syndromes. Furthermore, we collect a large-scale unlabelled textual corpus in the field of TCM and propose a domain-specific pre-trained language model, called ZY-BERT. We conducted experiments using deep neural networks to establish a strong performance baseline, reveal various challenges in SD, and prove the potential of domain-specific pre-trained language model. Our study and analysis reveal opportunities for incorporating computer science and linguistics knowledge to explore the empirical validity of TCM theories.
Key facts. Cited by 6 papers in the map (data through 7 Oct 2026). Builds on 18 of its 41 references that are in the map. First posted on arXiv 21 Mar 2022.
Builds on
18 of 41 references.
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6 more
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Citing papers per year: 2024: 2; 2025: 2; 2026: 2.
6 papers.
- 2024BianCang: A Traditional Chinese Medicine Large Language Modelcited by 11
- 2025TACL: Threshold-Adaptive Curriculum Learning Strategy for Enhancing Medical Text Understandingcited by 2
- 2024Traditional Chinese Medicine Case Analysis System for High-Level Semantic Abstraction: Optimized with Prompt and RAGcited by 1
- 2025A benchmark dataset for evaluating Syndrome Differentiation and Treatment in large language modelscited by 0
- 2026TCM-DiffRAG: Personalized Syndrome Differentiation Reasoning Method for Traditional Chinese Medicine based on Knowledge Graph and Chain of Thoughtcited by 0
- 2026Query-Conditioned Knowledge Alignment for Reliable Cross-System Medical Reasoningcited by 0
- 2026Query-Conditioned Knowledge Alignment for Reliable Cross-System Medical Reasoning18 May 2026
- 2026TCM-DiffRAG: Personalized Syndrome Differentiation Reasoning Method for Traditional Chinese Medicine based on Knowledge Graph and Chain of Thought26 Feb 2026
- 2025A benchmark dataset for evaluating Syndrome Differentiation and Treatment in large language models2 Dec 2025
- 2025TACL: Threshold-Adaptive Curriculum Learning Strategy for Enhancing Medical Text Understanding17 Oct 2025
- 2024Traditional Chinese Medicine Case Analysis System for High-Level Semantic Abstraction: Optimized with Prompt and RAG23 Nov 2024
- 2024BianCang: A Traditional Chinese Medicine Large Language Model17 Nov 2024