UNeXt: MLP-based Rapid Medical Image Segmentation Network
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Abstract (arXiv)
UNet and its latest extensions like TransUNet have been the leading medical image segmentation methods in recent years. However, these networks cannot be effectively adopted for rapid image segmentation in point-of-care applications as they are parameter-heavy, computationally complex and slow to use. To this end, we propose UNeXt which is a Convolutional multilayer perceptron (MLP) based network for image segmentation. We design UNeXt in an effective way with an early convolutional stage and a MLP stage in the latent stage. We propose a tokenized MLP block where we efficiently tokenize and project the convolutional features and use MLPs to model the representation. To further boost the performance, we propose shifting the channels of the inputs while feeding in to MLPs so as to focus on learning local dependencies. Using tokenized MLPs in latent space reduces the number of parameters and computational complexity while being able to result in a better representation to help segmentation. The network also consists of skip connections between various levels of encoder and decoder. We test UNeXt on multiple medical image segmentation datasets and show that we reduce the number of parameters by 72x, decrease the computational complexity by 68x, and improve the inference speed by 10x while also obtaining better segmentation performance over the state-of-the-art medical image segmentation architectures. Code is available at https://github.com/jeya-maria-jose/UNeXt-pytorch
Key facts. Cited by 185 papers in the map (data through 7 Oct 2026). Builds on 24 of its 26 references that are in the map. First posted on arXiv 9 Mar 2022.
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24 of 26 references.
References · 24
- 2018BERT: Pre-training of Deep Bidirectional Transformers for Language Understandingcited by 40,204
- 2020An Image is Worth 16x16 Words: Transformers for Image Recognition at Scalecited by 29,915
- 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,604
- 2016Gaussian Error Linear Units (GELUs)cited by 3,431
- 2021SegFormer: Simple and Efficient Design for Semantic Segmentation with Transformerscited by 2,923
- 2016V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentationcited by 2,284
- 2021TransUNet: Transformers Make Strong Encoders for Medical Image Segmentationcited by 1,552
- 2018UNet++: A Nested U-Net Architecture for Medical Image Segmentationcited by 1,518
- 20163D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotationcited by 1,471
- 2021MLP-Mixer: An all-MLP Architecture for Visioncited by 1,441
- 2021Swin-Unet: Unet-like Pure Transformer for Medical Image Segmentationcited by 1,218
- 2021UNETR: Transformers for 3D Medical Image Segmentationcited by 954
12 more
- 2017Skin Lesion Analysis Toward Melanoma Detection: A Challenge at the 2017 International Symposium on Biomedical Imaging (ISBI), Hosted by the International Skin Imaging Collaboration (ISIC)cited by 549
- 2021ResMLP: Feedforward networks for image classification with data-efficient trainingcited by 338
- 2017Road Extraction by Deep Residual U-Netcited by 333
- 2020UNet 3+: A Full-Scale Connected UNet for Medical Image Segmentationcited by 331
- 2020Axial-DeepLab: Stand-Alone Axial-Attention for Panoptic Segmentationcited by 326
- 2021Medical Transformer: Gated Axial-Attention for Medical Image Segmentationcited by 319
- 2021TransBTS: Multimodal Brain Tumor Segmentation Using Transformercited by 265
- 2021AS-MLP: An Axial Shifted MLP Architecture for Visioncited by 101
- 2021S2-MLP: Spatial-Shift MLP Architecture for Visioncited by 83
- 2020KiU-Net: Towards Accurate Segmentation of Biomedical Images using Over-complete Representationscited by 49
- 2018Y-Net: Joint Segmentation and Classification for Diagnosis of Breast Biopsy Imagescited by 42
- 2020KiU-Net: Overcomplete Convolutional Architectures for Biomedical Image and Volumetric Segmentationcited by 32
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Citing papers per year: 2022: 8; 2023: 39; 2024: 42; 2025: 56; 2026: 40.
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