mlsanityData to 7 Oct 2026

UNeXt: MLP-based Rapid Medical Image Segmentation Network

arXiv 2203.04967 ↗First posted 9 Mar 2022eess.IV cs.CVcited by 185

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Abstract (arXiv)

UNet and its latest extensions like TransUNet have been the leading medical image segmentation methods in recent years. However, these networks cannot be effectively adopted for rapid image segmentation in point-of-care applications as they are parameter-heavy, computationally complex and slow to use. To this end, we propose UNeXt which is a Convolutional multilayer perceptron (MLP) based network for image segmentation. We design UNeXt in an effective way with an early convolutional stage and a MLP stage in the latent stage. We propose a tokenized MLP block where we efficiently tokenize and project the convolutional features and use MLPs to model the representation. To further boost the performance, we propose shifting the channels of the inputs while feeding in to MLPs so as to focus on learning local dependencies. Using tokenized MLPs in latent space reduces the number of parameters and computational complexity while being able to result in a better representation to help segmentation. The network also consists of skip connections between various levels of encoder and decoder. We test UNeXt on multiple medical image segmentation datasets and show that we reduce the number of parameters by 72x, decrease the computational complexity by 68x, and improve the inference speed by 10x while also obtaining better segmentation performance over the state-of-the-art medical image segmentation architectures. Code is available at https://github.com/jeya-maria-jose/UNeXt-pytorch

Key facts. Cited by 185 papers in the map (data through 7 Oct 2026). Builds on 24 of its 26 references that are in the map. First posted on arXiv 9 Mar 2022.

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24 of 26 references.

References · 24

  1. 2018BERT: Pre-training of Deep Bidirectional Transformers for Language Understandingcited by 40,204
  2. 2020An Image is Worth 16x16 Words: Transformers for Image Recognition at Scalecited by 29,915
  3. 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,604
  4. 2016Gaussian Error Linear Units (GELUs)cited by 3,431
  5. 2021SegFormer: Simple and Efficient Design for Semantic Segmentation with Transformerscited by 2,923
  6. 2016V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentationcited by 2,284
  7. 2021TransUNet: Transformers Make Strong Encoders for Medical Image Segmentationcited by 1,552
  8. 2018UNet++: A Nested U-Net Architecture for Medical Image Segmentationcited by 1,518
  9. 20163D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotationcited by 1,471
  10. 2021MLP-Mixer: An all-MLP Architecture for Visioncited by 1,441
  11. 2021Swin-Unet: Unet-like Pure Transformer for Medical Image Segmentationcited by 1,218
  12. 2021UNETR: Transformers for 3D Medical Image Segmentationcited by 954
12 more
  1. 2017Skin Lesion Analysis Toward Melanoma Detection: A Challenge at the 2017 International Symposium on Biomedical Imaging (ISBI), Hosted by the International Skin Imaging Collaboration (ISIC)cited by 549
  2. 2021ResMLP: Feedforward networks for image classification with data-efficient trainingcited by 338
  3. 2017Road Extraction by Deep Residual U-Netcited by 333
  4. 2020UNet 3+: A Full-Scale Connected UNet for Medical Image Segmentationcited by 331
  5. 2020Axial-DeepLab: Stand-Alone Axial-Attention for Panoptic Segmentationcited by 326
  6. 2021Medical Transformer: Gated Axial-Attention for Medical Image Segmentationcited by 319
  7. 2021TransBTS: Multimodal Brain Tumor Segmentation Using Transformercited by 265
  8. 2021AS-MLP: An Axial Shifted MLP Architecture for Visioncited by 101
  9. 2021S2-MLP: Spatial-Shift MLP Architecture for Visioncited by 83
  10. 2020KiU-Net: Towards Accurate Segmentation of Biomedical Images using Over-complete Representationscited by 49
  11. 2018Y-Net: Joint Segmentation and Classification for Diagnosis of Breast Biopsy Imagescited by 42
  12. 2020KiU-Net: Overcomplete Convolutional Architectures for Biomedical Image and Volumetric Segmentationcited by 32

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Cited by year (2026 to 7 Oct)

Citing papers per year: 2022: 8; 2023: 39; 2024: 42; 2025: 56; 2026: 40.

185 papers.

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  1. 2024U-KAN Makes Strong Backbone for Medical Image Segmentation and Generationcited by 176
  2. 2023Ambiguous Medical Image Segmentation using Diffusion Modelscited by 92
  3. 2024EMCAD: Efficient Multi-scale Convolutional Attention Decoding for Medical Image Segmentationcited by 64
  4. 2022MALUNet: A Multi-Attention and Light-weight UNet for Skin Lesion Segmentationcited by 59
  5. 2023EGE-UNet: an Efficient Group Enhanced UNet for skin lesion segmentationcited by 53
  6. 2022Transforming medical imaging with Transformers? A comparative review of key properties, current progresses, and future perspectivescited by 32
  7. 2023CMUNeXt: An Efficient Medical Image Segmentation Network based on Large Kernel and Skip Fusioncited by 31
  8. 2022CMU-Net: A Strong ConvMixer-based Medical Ultrasound Image Segmentation Networkcited by 29
  9. 2023Advancing Medical Imaging with Language Models: A Journey from N-grams to ChatGPTcited by 28
  10. 2023TransNetR: Transformer-based Residual Network for Polyp Segmentation with Multi-Center Out-of-Distribution Testingcited by 26
  11. 2023ACC-UNet: A Completely Convolutional UNet model for the 2020scited by 26
  12. 2024Kolmogorov-Arnold Convolutions: Design Principles and Empirical Studiescited by 26
38 more
  1. 2022A Survey on Deep Learning for Skin Lesion Segmentationcited by 22
  2. 2023Alternate Diverse Teaching for Semi-supervised Medical Image Segmentationcited by 21
  3. 2025SegDINO: An Efficient Design for Medical and Natural Image Segmentation with DINO-V3cited by 20
  4. 2023Unite-Divide-Unite: Joint Boosting Trunk and Structure for High-accuracy Dichotomous Image Segmentationcited by 17
  5. 2023E2ENet: Dynamic Sparse Feature Fusion for Accurate and Efficient 3D Medical Image Segmentationcited by 16
  6. 2023Dual Cross-Attention for Medical Image Segmentationcited by 15
  7. 20231M parameters are enough? A lightweight CNN-based model for medical image segmentationcited by 15
  8. 2023Disruptive Autoencoders: Leveraging Low-level features for 3D Medical Image Pre-trainingcited by 15
  9. 2023TransNuSeg: A Lightweight Multi-Task Transformer for Nuclei Segmentationcited by 14
  10. 2023FedA3I: Annotation Quality-Aware Aggregation for Federated Medical Image Segmentation against Heterogeneous Annotation Noisecited by 14
  11. 2025BRISC: Annotated Dataset for Brain Tumor Segmentation and Classificationcited by 14
  12. 2025MK-UNet: Multi-kernel Lightweight CNN for Medical Image Segmentationcited by 12
  13. 2024Clustering Propagation for Universal Medical Image Segmentationcited by 11
  14. 2024CC-SAM: SAM with Cross-feature Attention and Context for Ultrasound Image Segmentationcited by 11
  15. 2023Learning with Explicit Shape Priors for Medical Image Segmentationcited by 10
  16. 2026ReCo-KD: Region- and Context-Aware Knowledge Distillation for Efficient 3D Medical Image Segmentationcited by 10
  17. 2025Rethinking Brain Tumor Segmentation from the Frequency Domain Perspectivecited by 9
  18. 2023Continuous U-Net: Faster, Greater and Noiselesscited by 8
  19. 2023Multi-Level Global Context Cross Consistency Model for Semi-Supervised Ultrasound Image Segmentation with Diffusion Modelcited by 8
  20. 2024OFMPNet: Deep End-to-End Model for Occupancy and Flow Prediction in Urban Environmentcited by 8
  21. 2024Polyp SAM 2: Advancing Zero shot Polyp Segmentation in Colorectal Cancer Detectioncited by 8
  22. 2025RWKV-UNet: Improving UNet with Long-Range Cooperation for Effective Medical Image Segmentationcited by 7
  23. 2025Pre-Trained LLM is a Semantic-Aware and Generalizable Segmentation Boostercited by 7
  24. 2023U-Netmer: U-Net meets Transformer for medical image segmentationcited by 6
  25. 2023Full-resolution MLPs Empower Medical Dense Predictioncited by 6
  26. 2024CT Liver Segmentation via PVT-based Encoding and Refined Decodingcited by 6
  27. 2024Chameleon: A Data-Efficient Generalist for Dense Visual Prediction in the Wildcited by 6
  28. 2024LV-UNet: A Lightweight and Vanilla Model for Medical Image Segmentationcited by 6
  29. 2024Self-Prompting Polyp Segmentation in Colonoscopy using Hybrid Yolo-SAM 2 Modelcited by 6
  30. 2024EViT-Unet: U-Net Like Efficient Vision Transformer for Medical Image Segmentation on Mobile and Edge Devicescited by 6
  31. 2025STPNet: Scale-aware Text Prompt Network for Medical Image Segmentationcited by 6
  32. 2025Mobile U-ViT: Revisiting large kernel and U-shaped ViT for efficient medical image segmentationcited by 6
  33. 2024MUCM-Net: A Mamba Powered UCM-Net for Skin Lesion Segmentationcited by 5
  34. 2024A Lightweight U-like Network Utilizing Neural Memory Ordinary Differential Equations for Slimming the Decodercited by 5
  35. 2025MambaVesselNet++: A Hybrid CNN-Mamba Architecture for Medical Image Segmentationcited by 5
  36. 2023MobileUtr: Revisiting the relationship between light-weight CNN and Transformer for efficient medical image segmentationcited by 4
  37. 2023SRSNetwork: Siamese Reconstruction-Segmentation Networks based on Dynamic-Parameter Convolutioncited by 4
  38. 2024MatchSeg: Towards Better Segmentation via Reference Image Matchingcited by 4

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