One shot PACS: Patient specific Anatomic Context and Shape prior aware recurrent registration-segmentation of longitudinal thoracic cone beam CTs
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Abstract (arXiv)
Image-guided adaptive lung radiotherapy requires accurate tumor and organs segmentation from during treatment cone-beam CT (CBCT) images. Thoracic CBCTs are hard to segment because of low soft-tissue contrast, imaging artifacts, respiratory motion, and large treatment induced intra-thoracic anatomic changes. Hence, we developed a novel Patient-specific Anatomic Context and Shape prior or PACS-aware 3D recurrent registration-segmentation network for longitudinal thoracic CBCT segmentation. Segmentation and registration networks were concurrently trained in an end-to-end framework and implemented with convolutional long-short term memory models. The registration network was trained in an unsupervised manner using pairs of planning CT (pCT) and CBCT images and produced a progressively deformed sequence of images. The segmentation network was optimized in a one-shot setting by combining progressively deformed pCT (anatomic context) and pCT delineations (shape context) with CBCT images. Our method, one-shot PACS was significantly more accurate (p<0.001) for tumor (DSC of 0.83 ± 0.08, surface DSC [sDSC] of 0.97 ± 0.06, and Hausdorff distance at 95th percentile [HD95] of 3.97±3.02mm) and the esophagus (DSC of 0.78 ± 0.13, sDSC of 0.90±0.14, HD95 of 3.22±2.02) segmentation than multiple methods. Ablation tests and comparative experiments were also done.
Key facts. Cited by 8 papers in the map (data through 7 Oct 2026). Builds on 20 of its 46 references that are in the map. First posted on arXiv 26 Jan 2022.
Builds on
20 of 46 references.
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8 more
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Citing papers per year: 2022: 1; 2023: 1; 2024: 4; 2025: 2.
8 papers.
- 2023SADIR: Shape-Aware Diffusion Models for 3D Image Reconstructioncited by 12
- 2024Multimodal Data Integration for Precision Oncology: Challenges and Future Directionscited by 10
- 2022Progressively refined deep joint registration segmentation (ProRSeg) of gastrointestinal organs at risk: Application to MRI and cone-beam CTcited by 5
- 2024ModeTv2: GPU-accelerated Motion Decomposition Transformer for Pairwise Optimization in Medical Image Registrationcited by 4
- 2024Tumor aware recurrent inter-patient deformable image registration of computed tomography scans with lung cancercited by 2
- 2025Modality-Aware Feature Matching in Visual and Vision-Language Applications: A Comprehensive Surveycited by 2
- 2024Distillation Learning Guided by Image Reconstruction for One-Shot Medical Image Segmentationcited by 1
- 2025Efficient Large-Deformation Medical Image Registration via Recurrent Dynamic Correlationcited by 0
- 2025Efficient Large-Deformation Medical Image Registration via Recurrent Dynamic Correlation25 Oct 2025
- 2025Modality-Aware Feature Matching in Visual and Vision-Language Applications: A Comprehensive Survey30 Jul 2025
- 2024Tumor aware recurrent inter-patient deformable image registration of computed tomography scans with lung cancer18 Sep 2024
- 2024Distillation Learning Guided by Image Reconstruction for One-Shot Medical Image Segmentation7 Aug 2024
- 2024Multimodal Data Integration for Precision Oncology: Challenges and Future Directions28 Jun 2024
- 2024ModeTv2: GPU-accelerated Motion Decomposition Transformer for Pairwise Optimization in Medical Image Registration25 Mar 2024
- 2023SADIR: Shape-Aware Diffusion Models for 3D Image Reconstruction6 Sep 2023
- 2022Progressively refined deep joint registration segmentation (ProRSeg) of gastrointestinal organs at risk: Application to MRI and cone-beam CT25 Oct 2022