SECP-Net: SE-Connection Pyramid Network of Organ At Risk Segmentation for Nasopharyngeal Carcinoma

Nasopharyngeal carcinoma (NPC) is a kind of malignant tumor. Accurate and automatic segmentation of organs at risk (OAR) of computed tomography (CT) images is clinically significant. In recent years, deep learning models represented by U-Net have been widely applied in medical image segmentation tasks, which can help doctors with reduction of workload and get accurate results more quickly. In OAR segmentation of NPC, the sizes of OAR are variable, especially, some of them are small. Traditional deep neural networks underperform during segmentation due to the lack use of global and multi-size information. This paper proposes a new SE-Connection Pyramid Network (SECP-Net). SECP-Net extracts global and multi-size information flow with se connection (SEC) modules and a pyramid structure of network for improving the segmentation performance, especially that of small organs. SECP-Net also designs an auto-context cascaded network to further improve the segmentation performance. Comparative experiments are conducted between SECP-Net and other recently methods on a dataset with CT images of head and neck. Five-fold cross validation is used to evaluate the performance based on two metrics, i.e., Dice and Jaccard similarity. Experimental results show that SECP-Net can achieve SOTA performance in this challenging task.