mlsanityData to 7 Oct 2026

Semi-Supervised Medical Image Segmentation via Cross Teaching between CNN and Transformer

arXiv 2112.04894 ↗First posted 9 Dec 2021eess.IV cs.CVcited by 99

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Abstract (arXiv)

Recently, deep learning with Convolutional Neural Networks (CNNs) and Transformers has shown encouraging results in fully supervised medical image segmentation. However, it is still challenging for them to achieve good performance with limited annotations for training. In this work, we present a very simple yet efficient framework for semi-supervised medical image segmentation by introducing the cross teaching between CNN and Transformer. Specifically, we simplify the classical deep co-training from consistency regularization to cross teaching, where the prediction of a network is used as the pseudo label to supervise the other network directly end-to-end. Considering the difference in learning paradigm between CNN and Transformer, we introduce the Cross Teaching between CNN and Transformer rather than just using CNNs. Experiments on a public benchmark show that our method outperforms eight existing semi-supervised learning methods just with a simpler framework. Notably, this work may be the first attempt to combine CNN and transformer for semi-supervised medical image segmentation and achieve promising results on a public benchmark. The code will be released at: https://github.com/HiLab-git/SSL4MIS.

Key facts. Cited by 99 papers in the map (data through 7 Oct 2026). Builds on 35 of its 46 references that are in the map. First posted on arXiv 9 Dec 2021.

Builds on

35 of 46 references.

References · 35

  1. 2020An Image is Worth 16x16 Words: Transformers for Image Recognition at Scalecited by 29,915
  2. 2019PyTorch: An Imperative Style, High-Performance Deep Learning Librarycited by 20,160
  3. 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,604
  4. 2021Swin Transformer: Hierarchical Vision Transformer using Shifted Windowscited by 12,082
  5. 2021Masked Autoencoders Are Scalable Vision Learnerscited by 7,339
  6. 2020Training data-efficient image transformers & distillation through attentioncited by 4,560
  7. 2021Pyramid Vision Transformer: A Versatile Backbone for Dense Prediction without Convolutionscited by 1,960
  8. 2021TransUNet: Transformers Make Strong Encoders for Medical Image Segmentationcited by 1,552
  9. 2021Swin-Unet: Unet-like Pure Transformer for Medical Image Segmentationcited by 1,218
  10. 2018Co-teaching: Robust Training of Deep Neural Networks with Extremely Noisy Labelscited by 1,053
  11. 2021UNETR: Transformers for 3D Medical Image Segmentationcited by 954
  12. 2021Transformer in Transformercited by 632
23 more
  1. 2018ADVENT: Adversarial Entropy Minimization for Domain Adaptation in Semantic Segmentationcited by 623
  2. 2021Semi-Supervised Semantic Segmentation with Cross Pseudo Supervisioncited by 462
  3. 2021Self-Supervised Pre-Training of Swin Transformers for 3D Medical Image Analysiscited by 418
  4. 2019Uncertainty-aware Self-ensembling Model for Semi-supervised 3D Left Atrium Segmentationcited by 378
  5. 2020Semi-Supervised Semantic Segmentation with Cross-Consistency Trainingcited by 375
  6. 2019Interpolation Consistency Training for Semi-Supervised Learningcited by 248
  7. 2021CoTr: Efficiently Bridging CNN and Transformer for 3D Medical Image Segmentationcited by 227
  8. 2020Semi-supervised Medical Image Segmentation through Dual-task Consistencycited by 215
  9. 2018Deep Co-Training for Semi-Supervised Image Recognitioncited by 145
  10. 2019Transformation Consistent Self-ensembling Model for Semi-supervised Medical Image Segmentationcited by 138
  11. 2017DeepIGeoS: A Deep Interactive Geodesic Framework for Medical Image Segmentationcited by 110
  12. 2020Efficient Semi-Supervised Gross Target Volume of Nasopharyngeal Carcinoma Segmentation via Uncertainty Rectified Pyramid Consistencycited by 102
  13. 2021SimCVD: Simple Contrastive Voxel-Wise Representation Distillation for Semi-Supervised Medical Image Segmentationcited by 86
  14. 2020Uncertainty-aware multi-view co-training for semi-supervised medical image segmentation and domain adaptationcited by 81
  15. 2021Recurrent Mask Refinement for Few-Shot Medical Image Segmentationcited by 63
  16. 2019Multi-Task Attention-Based Semi-Supervised Learning for Medical Image Segmentationcited by 55
  17. 2021Momentum Contrastive Voxel-wise Representation Learning for Semi-supervised Volumetric Medical Image Segmentationcited by 49
  18. 2021MIDeepSeg: Minimally Interactive Segmentation of Unseen Objects from Medical Images Using Deep Learningcited by 45
  19. 2018Semi-Supervised Multi-Organ Segmentation via Deep Multi-Planar Co-Trainingcited by 40
  20. 2021Every Annotation Counts: Multi-label Deep Supervision for Medical Image Segmentationcited by 37
  21. 2021Self-Paced Contrastive Learning for Semi-supervised Medical Image Segmentation with Meta-labelscited by 32
  22. 2019Curriculum semi-supervised segmentationcited by 27
  23. 2021Semi-Supervised Segmentation of Radiation-Induced Pulmonary Fibrosis from Lung CT Scans with Multi-Scale Guided Dense Attentioncited by 14

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Cited by year (2026 to 7 Oct)

Citing papers per year: 2022: 10; 2023: 30; 2024: 27; 2025: 22; 2026: 10.

99 papers.

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  1. 2022Revisiting Weak-to-Strong Consistency in Semi-Supervised Semantic Segmentationcited by 177
  2. 2022Learning with Limited Annotations: A Survey on Deep Semi-Supervised Learning for Medical Image Segmentationcited by 74
  3. 2023Advances in Medical Image Analysis with Vision Transformers: A Comprehensive Reviewcited by 62
  4. 2023Towards Label-free Scene Understanding by Vision Foundation Modelscited by 54
  5. 2022Transformers in Medical Image Analysis: A Reviewcited by 41
  6. 2022Transforming medical imaging with Transformers? A comparative review of key properties, current progresses, and future perspectivescited by 32
  7. 2023A comprehensive survey on deep active learning in medical image analysiscited by 32
  8. 2023Correlation-Aware Mutual Learning for Semi-supervised Medical Image Segmentationcited by 30
  9. 2024Weak-Mamba-UNet: Visual Mamba Makes CNN and ViT Work Better for Scribble-based Medical Image Segmentationcited by 29
  10. 2024Adaptive Bidirectional Displacement for Semi-Supervised Medical Image Segmentationcited by 29
  11. 2023RCPS: Rectified Contrastive Pseudo Supervision for Semi-Supervised Medical Image Segmentationcited by 27
  12. 2023Diverse Cotraining Makes Strong Semi-Supervised Segmentorcited by 26
38 more
  1. 2024ScribFormer: Transformer Makes CNN Work Better for Scribble-based Medical Image Segmentationcited by 24
  2. 2023ScribbleVC: Scribble-supervised Medical Image Segmentation with Vision-Class Embeddingcited by 23
  3. 2023Alternate Diverse Teaching for Semi-supervised Medical Image Segmentationcited by 21
  4. 2024Semi-Mamba-UNet: Pixel-Level Contrastive and Pixel-Level Cross-Supervised Visual Mamba-based UNet for Semi-Supervised Medical Image Segmentationcited by 20
  5. 2022Transformer-CNN Cohort: Semi-supervised Semantic Segmentation by the Best of Both Studentscited by 16
  6. 2023Orthogonal Annotation Benefits Barely-supervised Medical Image Segmentationcited by 15
  7. 2022PyMIC: A deep learning toolkit for annotation-efficient medical image segmentationcited by 14
  8. 2023Label-Efficient Deep Learning in Medical Image Analysis: Challenges and Future Directionscited by 14
  9. 2024DiffRect: Latent Diffusion Label Rectification for Semi-supervised Medical Image Segmentationcited by 14
  10. 2022Translation Consistent Semi-supervised Segmentation for 3D Medical Imagescited by 13
  11. 2022When CNN Meet with ViT: Towards Semi-Supervised Learning for Multi-Class Medical Image Semantic Segmentationcited by 13
  12. 2024Beyond Pixels: Semi-Supervised Semantic Segmentation with a Multi-scale Patch-based Multi-Label Classifiercited by 12
  13. 2022CTooth+: A Large-scale Dental Cone Beam Computed Tomography Dataset and Benchmark for Tooth Volume Segmentationcited by 11
  14. 2023Compete to Win: Enhancing Pseudo Labels for Barely-supervised Medical Image Segmentationcited by 10
  15. 2024Intrapartum Ultrasound Image Segmentation of Pubic Symphysis and Fetal Head Using Dual Student-Teacher Framework with CNN-ViT Collaborative Learningcited by 9
  16. 2024SDCL: Students Discrepancy-Informed Correction Learning for Semi-supervised Medical Image Segmentationcited by 9
  17. 2023Multi-Level Global Context Cross Consistency Model for Semi-Supervised Ultrasound Image Segmentation with Diffusion Modelcited by 8
  18. 2023Semi-supervised Pathological Image Segmentation via Cross Distillation of Multiple Attentionscited by 8
  19. 2024Generative AI Enables Medical Image Segmentation in Ultra Low-Data Regimescited by 8
  20. 20233D Medical Image Segmentation with Sparse Annotation via Cross-Teaching between 3D and 2D Networkscited by 7
  21. 2023Data efficient deep learning for medical image analysis: A surveycited by 6
  22. 2025MetaSSL: A General Heterogeneous Loss for Semi-Supervised Medical Image Segmentationcited by 6
  23. 2023Shifting to Machine Supervision: Annotation-Efficient Semi and Self-Supervised Learning for Automatic Medical Image Segmentation and Classificationcited by 5
  24. 2024Multi-modal Data Binding for Survival Analysis Modeling with Incomplete Data and Annotationscited by 5
  25. 2024XNet v2: Fewer Limitations, Better Results and Greater Universalitycited by 5
  26. 2025Uncertainty-aware Cross-training for Semi-supervised Medical Image Segmentationcited by 5
  27. 2023Multi-Scale Cross Contrastive Learning for Semi-Supervised Medical Image Segmentationcited by 4
  28. 2025Learning Disentangled Stain and Structural Representations for Semi-Supervised Histopathology Segmentationcited by 4
  29. 2025Semi-MoE: Mixture-of-Experts meets Semi-Supervised Histopathology Segmentationcited by 4
  30. 2023Towards more precise automatic analysis: a comprehensive survey of deep learning-based multi-organ segmentationcited by 3
  31. 2023Inherent Consistent Learning for Accurate Semi-supervised Medical Image Segmentationcited by 3
  32. 2023Confidence-Guided Semi-supervised Learning in Land Cover Classificationcited by 3
  33. 2024Segmenting Medical Images with Limited Datacited by 3
  34. 2024Prototype Learning Guided Hybrid Network for Breast Tumor Segmentation in DCE-MRIcited by 3
  35. 2025Balancing Multi-Target Semi-Supervised Medical Image Segmentation with Collaborative Generalist and Specialistscited by 3
  36. 2025HDC: Hierarchical Distillation for Multi-level Noisy Consistency in Semi-Supervised Fetal Ultrasound Segmentationcited by 3
  37. 2023Expectation Maximization Pseudo Labelscited by 2
  38. 2023Rethinking Data Perturbation and Model Stabilization for Semi-supervised Medical Image Segmentationcited by 2

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