Bounding Box Tightness Prior for Weakly Supervised Image Segmentation
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Abstract (arXiv)
This paper presents a weakly supervised image segmentation method that adopts tight bounding box annotations. It proposes generalized multiple instance learning (MIL) and smooth maximum approximation to integrate the bounding box tightness prior into the deep neural network in an end-to-end manner. In generalized MIL, positive bags are defined by parallel crossing lines with a set of different angles, and negative bags are defined as individual pixels outside of any bounding boxes. Two variants of smooth maximum approximation, i.e., α-softmax function and α-quasimax function, are exploited to conquer the numeral instability introduced by maximum function of bag prediction. The proposed approach was evaluated on two pubic medical datasets using Dice coefficient. The results demonstrate that it outperforms the state-of-the-art methods. The codes are available at urlhttps://github.com/wangjuan313/wsis-boundingbox.
Key facts. Cited by 19 papers in the map (data through 14 Oct 2026). Builds on 13 of its 21 references that are in the map. First posted on arXiv 3 Oct 2021.
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13 of 21 references.
References · 13
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Citing papers per year: 2022: 3; 2023: 5; 2024: 8; 2025: 3.
19 papers.
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- 2023Label-Efficient Deep Learning in Medical Image Analysis: Challenges and Future Directionscited by 16
- 2024BoNuS: Boundary Mining for Nuclei Segmentation with Partial Point Labelscited by 8
- 2023Data efficient deep learning for medical image analysis: A surveycited by 6
- 2024FedLPPA: Learning Personalized Prompt and Aggregation for Federated Weakly-supervised Medical Image Segmentationcited by 6
- 2024MonoBox: Tightness-free Box-supervised Polyp Segmentation using Monotonicity Constraintcited by 5
- 2024Automating MedSAM by Learning Prompts with Weak Few-Shot Supervisioncited by 5
- 2024Beyond Pixel-Wise Supervision for Medical Image Segmentation: From Traditional Models to Foundation Modelscited by 4
- 2023Weakly Supervised Image Segmentation Beyond Tight Bounding Box Annotationscited by 3
- 2024From Few to More: Scribble-based Medical Image Segmentation via Masked Context Modeling and Continuous Pseudo Labelscited by 3
- 2025COIN: Confidence Score-Guided Distillation for Annotation-Free Cell Segmentationcited by 3
- 2023IBoxCLA: Towards Robust Box-supervised Segmentation of Polyp via Improved Box-dice and Contrastive Latent-anchorscited by 2
- 2024OOD-SEG: Exploiting out-of-distribution detection techniques for learning image segmentation from sparse multi-class positive-only annotationscited by 2
7 more
- 2025Prompt learning with bounding box constraints for medical image segmentationcited by 2
- 2022Polar Transformation Based Multiple Instance Learning Assisting Weakly Supervised Image Segmentation With Loose Bounding Box Annotationscited by 1
- 2022Cardiac Adipose Tissue Segmentation via Image-Level Annotationscited by 1
- 2023BoxCell: Leveraging SAM for Cell Segmentation with Box Supervisioncited by 1
- 2024Weakly-Supervised Learning via Multi-Lateral Decoder Branching for Tool Segmentation in Robot-Assisted Cardiovascular Catheterizationcited by 1
- 2022Coarse Retinal Lesion Annotations Refinement via Prototypical Learningcited by 0
- 2025Label tree semantic losses for rich multi-class medical image segmentationcited by 0
- 2025Label tree semantic losses for rich multi-class medical image segmentation21 Jul 2025
- 2025Prompt learning with bounding box constraints for medical image segmentation3 Jul 2025
- 2025COIN: Confidence Score-Guided Distillation for Annotation-Free Cell Segmentation14 Mar 2025
- 2024OOD-SEG: Exploiting out-of-distribution detection techniques for learning image segmentation from sparse multi-class positive-only annotations14 Nov 2024
- 2024Automating MedSAM by Learning Prompts with Weak Few-Shot Supervision30 Sep 2024
- 2024From Few to More: Scribble-based Medical Image Segmentation via Masked Context Modeling and Continuous Pseudo Labels23 Aug 2024
- 2024Beyond Pixel-Wise Supervision for Medical Image Segmentation: From Traditional Models to Foundation Models20 Apr 2024
- 2024Weakly-Supervised Learning via Multi-Lateral Decoder Branching for Tool Segmentation in Robot-Assisted Cardiovascular Catheterization11 Apr 2024
- 2024MonoBox: Tightness-free Box-supervised Polyp Segmentation using Monotonicity Constraint1 Apr 2024
- 2024FedLPPA: Learning Personalized Prompt and Aggregation for Federated Weakly-supervised Medical Image Segmentation27 Feb 2024
- 2024BoNuS: Boundary Mining for Nuclei Segmentation with Partial Point Labels15 Jan 2024
- 2023BoxCell: Leveraging SAM for Cell Segmentation with Box Supervision29 Nov 2023
7 more
- 2023IBoxCLA: Towards Robust Box-supervised Segmentation of Polyp via Improved Box-dice and Contrastive Latent-anchors11 Oct 2023
- 2023Data efficient deep learning for medical image analysis: A survey10 Oct 2023
- 2023Label-Efficient Deep Learning in Medical Image Analysis: Challenges and Future Directions22 Mar 2023
- 2023Weakly Supervised Image Segmentation Beyond Tight Bounding Box Annotations28 Jan 2023
- 2022Coarse Retinal Lesion Annotations Refinement via Prototypical Learning30 Aug 2022
- 2022Cardiac Adipose Tissue Segmentation via Image-Level Annotations9 Jun 2022
- 2022Polar Transformation Based Multiple Instance Learning Assisting Weakly Supervised Image Segmentation With Loose Bounding Box Annotations3 Mar 2022
- 2023Label-Efficient Deep Learning in Medical Image Analysis: Challenges and Future Directionscited by 16
- 2024BoNuS: Boundary Mining for Nuclei Segmentation with Partial Point Labelscited by 8
- 2023Data efficient deep learning for medical image analysis: A surveycited by 6
- 2024FedLPPA: Learning Personalized Prompt and Aggregation for Federated Weakly-supervised Medical Image Segmentationcited by 6
- 2024MonoBox: Tightness-free Box-supervised Polyp Segmentation using Monotonicity Constraintcited by 5
- 2024Automating MedSAM by Learning Prompts with Weak Few-Shot Supervisioncited by 5
- 2024Beyond Pixel-Wise Supervision for Medical Image Segmentation: From Traditional Models to Foundation Modelscited by 4
- 2023Weakly Supervised Image Segmentation Beyond Tight Bounding Box Annotationscited by 3
- 2024From Few to More: Scribble-based Medical Image Segmentation via Masked Context Modeling and Continuous Pseudo Labelscited by 3
- 2025COIN: Confidence Score-Guided Distillation for Annotation-Free Cell Segmentationcited by 3
- 2023IBoxCLA: Towards Robust Box-supervised Segmentation of Polyp via Improved Box-dice and Contrastive Latent-anchorscited by 2
- 2024OOD-SEG: Exploiting out-of-distribution detection techniques for learning image segmentation from sparse multi-class positive-only annotationscited by 2
12 most cited of 19 All 19 (JSON)
- 2025Label tree semantic losses for rich multi-class medical image segmentation21 Jul 2025
- 2025Prompt learning with bounding box constraints for medical image segmentation3 Jul 2025
- 2025COIN: Confidence Score-Guided Distillation for Annotation-Free Cell Segmentation14 Mar 2025
- 2024OOD-SEG: Exploiting out-of-distribution detection techniques for learning image segmentation from sparse multi-class positive-only annotations14 Nov 2024
- 2024Automating MedSAM by Learning Prompts with Weak Few-Shot Supervision30 Sep 2024
- 2024From Few to More: Scribble-based Medical Image Segmentation via Masked Context Modeling and Continuous Pseudo Labels23 Aug 2024
- 2024Beyond Pixel-Wise Supervision for Medical Image Segmentation: From Traditional Models to Foundation Models20 Apr 2024
- 2024Weakly-Supervised Learning via Multi-Lateral Decoder Branching for Tool Segmentation in Robot-Assisted Cardiovascular Catheterization11 Apr 2024
- 2024MonoBox: Tightness-free Box-supervised Polyp Segmentation using Monotonicity Constraint1 Apr 2024
- 2024FedLPPA: Learning Personalized Prompt and Aggregation for Federated Weakly-supervised Medical Image Segmentation27 Feb 2024
- 2024BoNuS: Boundary Mining for Nuclei Segmentation with Partial Point Labels15 Jan 2024
- 2023BoxCell: Leveraging SAM for Cell Segmentation with Box Supervision29 Nov 2023
12 newest of 19 All 19 (JSON)