VinDr-SpineXR: A deep learning framework for spinal lesions detection and classification from radiographs
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Abstract (arXiv)
Radiographs are used as the most important imaging tool for identifying spine anomalies in clinical practice. The evaluation of spinal bone lesions, however, is a challenging task for radiologists. This work aims at developing and evaluating a deep learning-based framework, named VinDr-SpineXR, for the classification and localization of abnormalities from spine X-rays. First, we build a large dataset, comprising 10,468 spine X-ray images from 5,000 studies, each of which is manually annotated by an experienced radiologist with bounding boxes around abnormal findings in 13 categories. Using this dataset, we then train a deep learning classifier to determine whether a spine scan is abnormal and a detector to localize 7 crucial findings amongst the total 13. The VinDr-SpineXR is evaluated on a test set of 2,078 images from 1,000 studies, which is kept separate from the training set. It demonstrates an area under the receiver operating characteristic curve (AUROC) of 88.61% (95% CI 87.19%, 90.02%) for the image-level classification task and a mean average precision ([email protected]) of 33.56% for the lesion-level localization task. These results serve as a proof of concept and set a baseline for future research in this direction. To encourage advances, the dataset, codes, and trained deep learning models are made publicly available.
Key facts. Cited by 20 papers in the map (data through 14 Oct 2026). Builds on 8 of its 38 references that are in the map. First posted on arXiv 24 Jun 2021.
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8 of 38 references.
References · 8
- 2015Faster R-CNN: Towards Real-Time Object Detection with Region Proposal Networkscited by 9,639
- 2016Densely Connected Convolutional Networkscited by 6,720
- 2019EfficientDet: Scalable and Efficient Object Detectioncited by 1,020
- 2020Sparse R-CNN: End-to-End Object Detection with Learnable Proposalscited by 495
- 2017CheXNet: Radiologist-Level Pneumonia Detection on Chest X-Rays with Deep Learningcited by 461
- 2017Deep Learning for Medical Image Analysiscited by 401
- 2019Learning Data Augmentation Strategies for Object Detectioncited by 139
- 2020A New Window Loss Function for Bone Fracture Detection and Localization in X-ray Images with Point-based Annotationcited by 4
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Citing papers per year: 2022: 7; 2023: 5; 2024: 4; 2025: 3; 2026: 1.
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- 2024Interpretable Bilingual Multimodal Large Language Model for Diverse Biomedical Taskscited by 24
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- 2024Large Language Model Benchmarks in Medical Taskscited by 17
- 2022Learning from Multiple Expert Annotators for Enhancing Anomaly Detection in Medical Image Analysiscited by 13
- 2022An Accurate and Explainable Deep Learning System Improves Interobserver Agreement in the Interpretation of Chest Radiographcited by 7
- 2023K-Diag: Knowledge-enhanced Disease Diagnosis in Radiographic Imagingcited by 6
- 2022Learning to diagnose common thorax diseases on chest radiographs from radiology reports in Vietnamesecited by 5
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- 2023Improving Object Detection in Medical Image Analysis through Multiple Expert Annotators: An Empirical Investigationcited by 1
- 2024Spinal Osteophyte Detection via Robust Patch Extraction on minimally annotated X-rayscited by 1
- 2022Generative Adversarial Network Based Synthetic Learning and a Novel Domain Relevant Loss Term for Spine Radiographscited by 0
- 2025SpineBench: Benchmarking Multimodal LLMs for Spinal Pathology Analysiscited by 0
- 2025MedGEN-Bench: A Contextually Entangled Benchmark for Open-ended Multimodal Medical Generationcited by 0
- 2026Project Imaging-X: A Survey of 1000+ Open-Access Medical Imaging Datasets for Foundation Model Development29 Mar 2026
- 2025MedGEN-Bench: A Contextually Entangled Benchmark for Open-ended Multimodal Medical Generation17 Nov 2025
- 2025SpineBench: Benchmarking Multimodal LLMs for Spinal Pathology Analysis14 Oct 2025
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- 2024Large Language Model Benchmarks in Medical Tasks28 Oct 2024
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- 2024MedViLaM: A multimodal large language model with advanced generalizability and explainability for medical data understanding and generation29 Sep 2024
- 2024Spinal Osteophyte Detection via Robust Patch Extraction on minimally annotated X-rays29 Feb 2024
- 2023Large-scale Long-tailed Disease Diagnosis on Radiology Images26 Dec 2023
- 2023MoCo-Transfer: Investigating out-of-distribution contrastive learning for limited-data domains15 Nov 2023
- 2023Towards Generalist Foundation Model for Radiology by Leveraging Web-scale 2D&3D Medical Data4 Aug 2023
- 2023Improving Object Detection in Medical Image Analysis through Multiple Expert Annotators: An Empirical Investigation29 Mar 2023
8 more
- 2023K-Diag: Knowledge-enhanced Disease Diagnosis in Radiographic Imaging22 Feb 2023
- 2022Learning to diagnose common thorax diseases on chest radiographs from radiology reports in Vietnamese11 Sep 2022
- 2022An Accurate and Explainable Deep Learning System Improves Interobserver Agreement in the Interpretation of Chest Radiograph6 Aug 2022
- 2022Slice-level Detection of Intracranial Hemorrhage on CT Using Deep Descriptors of Adjacent Slices5 Aug 2022
- 2022Automating Detection of Papilledema in Pediatric Fundus Images with Explainable Machine Learning10 Jul 2022
- 2022Explainable Deep Learning Methods in Medical Image Classification: A Survey10 May 2022
- 2022Generative Adversarial Network Based Synthetic Learning and a Novel Domain Relevant Loss Term for Spine Radiographs5 May 2022
- 2022Learning from Multiple Expert Annotators for Enhancing Anomaly Detection in Medical Image Analysis20 Mar 2022
- 2024Interpretable Bilingual Multimodal Large Language Model for Diverse Biomedical Taskscited by 24
- 2024MedViLaM: A multimodal large language model with advanced generalizability and explainability for medical data understanding and generationcited by 17
- 2025SpineBench: Benchmarking Multimodal LLMs for Spinal Pathology Analysiscited by 0
- 2025MedGEN-Bench: A Contextually Entangled Benchmark for Open-ended Multimodal Medical Generationcited by 0
- 2025MedGEN-Bench: A Contextually Entangled Benchmark for Open-ended Multimodal Medical Generation17 Nov 2025
- 2025SpineBench: Benchmarking Multimodal LLMs for Spinal Pathology Analysis14 Oct 2025
- 2024Interpretable Bilingual Multimodal Large Language Model for Diverse Biomedical Tasks24 Oct 2024
- 2024MedViLaM: A multimodal large language model with advanced generalizability and explainability for medical data understanding and generation29 Sep 2024
- 2023Towards Generalist Foundation Model for Radiology by Leveraging Web-scale 2D&3D Medical Datacited by 179
- 2022Explainable Deep Learning Methods in Medical Image Classification: A Surveycited by 32
- 2023Large-scale Long-tailed Disease Diagnosis on Radiology Imagescited by 17
- 2024Large Language Model Benchmarks in Medical Taskscited by 17
- 2022Learning from Multiple Expert Annotators for Enhancing Anomaly Detection in Medical Image Analysiscited by 13
- 2022An Accurate and Explainable Deep Learning System Improves Interobserver Agreement in the Interpretation of Chest Radiographcited by 7
- 2023K-Diag: Knowledge-enhanced Disease Diagnosis in Radiographic Imagingcited by 6
- 2022Learning to diagnose common thorax diseases on chest radiographs from radiology reports in Vietnamesecited by 5
- 2023MoCo-Transfer: Investigating out-of-distribution contrastive learning for limited-data domainscited by 3
- 2022Automating Detection of Papilledema in Pediatric Fundus Images with Explainable Machine Learningcited by 2
- 2025Multi-Modal Explainable Medical AI Assistant for Trustworthy Human-AI Collaborationcited by 2
- 2026Project Imaging-X: A Survey of 1000+ Open-Access Medical Imaging Datasets for Foundation Model Developmentcited by 2
12 most cited of 16 All 16 (JSON)
- 2026Project Imaging-X: A Survey of 1000+ Open-Access Medical Imaging Datasets for Foundation Model Development29 Mar 2026
- 2025Multi-Modal Explainable Medical AI Assistant for Trustworthy Human-AI Collaboration11 May 2025
- 2024Large Language Model Benchmarks in Medical Tasks28 Oct 2024
- 2024Spinal Osteophyte Detection via Robust Patch Extraction on minimally annotated X-rays29 Feb 2024
- 2023Large-scale Long-tailed Disease Diagnosis on Radiology Images26 Dec 2023
- 2023MoCo-Transfer: Investigating out-of-distribution contrastive learning for limited-data domains15 Nov 2023
- 2023Towards Generalist Foundation Model for Radiology by Leveraging Web-scale 2D&3D Medical Data4 Aug 2023
- 2023Improving Object Detection in Medical Image Analysis through Multiple Expert Annotators: An Empirical Investigation29 Mar 2023
- 2023K-Diag: Knowledge-enhanced Disease Diagnosis in Radiographic Imaging22 Feb 2023
- 2022Learning to diagnose common thorax diseases on chest radiographs from radiology reports in Vietnamese11 Sep 2022
- 2022An Accurate and Explainable Deep Learning System Improves Interobserver Agreement in the Interpretation of Chest Radiograph6 Aug 2022
- 2022Slice-level Detection of Intracranial Hemorrhage on CT Using Deep Descriptors of Adjacent Slices5 Aug 2022
12 newest of 16 All 16 (JSON)