CliniQG4QA: Generating Diverse Questions for Domain Adaptation of Clinical Question Answering
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Abstract (arXiv)
Clinical question answering (QA) aims to automatically answer questions from medical professionals based on clinical texts. Studies show that neural QA models trained on one corpus may not generalize well to new clinical texts from a different institute or a different patient group, where large-scale QA pairs are not readily available for model retraining. To address this challenge, we propose a simple yet effective framework, CliniQG4QA, which leverages question generation (QG) to synthesize QA pairs on new clinical contexts and boosts QA models without requiring manual annotations. In order to generate diverse types of questions that are essential for training QA models, we further introduce a seq2seq-based question phrase prediction (QPP) module that can be used together with most existing QG models to diversify the generation. Our comprehensive experiment results show that the QA corpus generated by our framework can improve QA models on the new contexts (up to 8% absolute gain in terms of Exact Match), and that the QPP module plays a crucial role in achieving the gain.
Key facts. Cited by 26 papers in the map (data through 7 Oct 2026). First posted on arXiv 30 Oct 2020.
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Citing papers per year: 2021: 3; 2022: 7; 2023: 7; 2024: 3; 2025: 6.
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- 2024Benchmarking Large Language Models on Answering and Explaining Challenging Medical Questionscited by 106
- 2023MedAlign: A Clinician-Generated Dataset for Instruction Following with Electronic Medical Recordscited by 54
- 2021Biomedical Question Answering: A Survey of Approaches and Challengescited by 46
- 2024EHRNoteQA: An LLM Benchmark for Real-World Clinical Practice Using Discharge Summariescited by 33
- 2023Task-Adaptive Tokenization: Enhancing Long-Form Text Generation Efficacy in Mental Health and Beyondcited by 22
- 2023PaniniQA: Enhancing Patient Education Through Interactive Question Answeringcited by 21
- 2022Question Generation for Reading Comprehension Assessment by Modeling How and What to Askcited by 20
- 2022DrugEHRQA: A Question Answering Dataset on Structured and Unstructured Electronic Health Records For Medicine Related Queriescited by 17
- 2022Learning to Ask Like a Physiciancited by 16
- 2025Learning Facts at Scale with Active Readingcited by 11
- 2025Experience Retrieval-Augmentation with Electronic Health Records Enables Accurate Discharge QAcited by 9
- 2023Question Answering for Electronic Health Records: A Scoping Review of datasets and modelscited by 7
14 more
- 2023MOKA: Moral Knowledge Augmentation for Moral Event Extractioncited by 7
- 2022Generative Entity-to-Entity Stance Detection with Knowledge Graph Augmentationcited by 6
- 2025RGAR: Recurrence Generation-augmented Retrieval for Factual-aware Medical Question Answeringcited by 5
- 2024Dynamic Q&A of Clinical Documents with Large Language Modelscited by 4
- 2021Automated question generation and question answering from Turkish textscited by 3
- 2022BioADAPT-MRC: Adversarial Learning-based Domain Adaptation Improves Biomedical Machine Reading Comprehension Taskcited by 3
- 2022Source-Free Domain Adaptation for Question Answering with Masked Self-trainingcited by 3
- 2021Towards More Robust Natural Language Understandingcited by 2
- 2022QA Domain Adaptation using Hidden Space Augmentation and Self-Supervised Contrastive Adaptationcited by 2
- 2023JCSE: Contrastive Learning of Japanese Sentence Embeddings and Its Applicationscited by 1
- 2025Domain Adaptation for Japanese Sentence Embeddings with Contrastive Learning based on Synthetic Sentence Generationcited by 1
- 2025Domain-Specific Data Generation Framework for RAG Adaptationcited by 1
- 2023XAIQA: Explainer-Based Data Augmentation for Extractive Question Answeringcited by 0
- 2025Investigating LLM Capabilities on Long Context Comprehension for Medical Question Answeringcited by 0
- 2025Investigating LLM Capabilities on Long Context Comprehension for Medical Question Answering21 Oct 2025
- 2025Domain-Specific Data Generation Framework for RAG Adaptation13 Oct 2025
- 2025Learning Facts at Scale with Active Reading13 Aug 2025
- 2025Experience Retrieval-Augmentation with Electronic Health Records Enables Accurate Discharge QA23 Mar 2025
- 2025Domain Adaptation for Japanese Sentence Embeddings with Contrastive Learning based on Synthetic Sentence Generation12 Mar 2025
- 2025RGAR: Recurrence Generation-augmented Retrieval for Factual-aware Medical Question Answering19 Feb 2025
- 2024Benchmarking Large Language Models on Answering and Explaining Challenging Medical Questions28 Feb 2024
- 2024EHRNoteQA: An LLM Benchmark for Real-World Clinical Practice Using Discharge Summaries25 Feb 2024
- 2024Dynamic Q&A of Clinical Documents with Large Language Models19 Jan 2024
- 2023XAIQA: Explainer-Based Data Augmentation for Extractive Question Answering6 Dec 2023
- 2023MOKA: Moral Knowledge Augmentation for Moral Event Extraction16 Nov 2023
- 2023Question Answering for Electronic Health Records: A Scoping Review of datasets and models12 Oct 2023
14 more
- 2023Task-Adaptive Tokenization: Enhancing Long-Form Text Generation Efficacy in Mental Health and Beyond9 Oct 2023
- 2023MedAlign: A Clinician-Generated Dataset for Instruction Following with Electronic Medical Records27 Aug 2023
- 2023PaniniQA: Enhancing Patient Education Through Interactive Question Answering7 Aug 2023
- 2023JCSE: Contrastive Learning of Japanese Sentence Embeddings and Its Applications19 Jan 2023
- 2022Source-Free Domain Adaptation for Question Answering with Masked Self-training19 Dec 2022
- 2022Generative Entity-to-Entity Stance Detection with Knowledge Graph Augmentation2 Nov 2022
- 2022QA Domain Adaptation using Hidden Space Augmentation and Self-Supervised Contrastive Adaptation19 Oct 2022
- 2022Learning to Ask Like a Physician6 Jun 2022
- 2022DrugEHRQA: A Question Answering Dataset on Structured and Unstructured Electronic Health Records For Medicine Related Queries3 May 2022
- 2022Question Generation for Reading Comprehension Assessment by Modeling How and What to Ask6 Apr 2022
- 2022BioADAPT-MRC: Adversarial Learning-based Domain Adaptation Improves Biomedical Machine Reading Comprehension Task26 Feb 2022
- 2021Towards More Robust Natural Language Understanding1 Dec 2021
- 2021Automated question generation and question answering from Turkish texts11 Nov 2021
- 2021Biomedical Question Answering: A Survey of Approaches and Challenges10 Feb 2021
- 2025Domain-Specific Data Generation Framework for RAG Adaptation13 Oct 2025
- 2024Benchmarking Large Language Models on Answering and Explaining Challenging Medical Questionscited by 106
- 2023MedAlign: A Clinician-Generated Dataset for Instruction Following with Electronic Medical Recordscited by 54
- 2021Biomedical Question Answering: A Survey of Approaches and Challengescited by 46
- 2024EHRNoteQA: An LLM Benchmark for Real-World Clinical Practice Using Discharge Summariescited by 33
- 2023Task-Adaptive Tokenization: Enhancing Long-Form Text Generation Efficacy in Mental Health and Beyondcited by 22
- 2023PaniniQA: Enhancing Patient Education Through Interactive Question Answeringcited by 21
- 2022Question Generation for Reading Comprehension Assessment by Modeling How and What to Askcited by 20
- 2022DrugEHRQA: A Question Answering Dataset on Structured and Unstructured Electronic Health Records For Medicine Related Queriescited by 17
- 2022Learning to Ask Like a Physiciancited by 16
- 2025Learning Facts at Scale with Active Readingcited by 11
- 2023Question Answering for Electronic Health Records: A Scoping Review of datasets and modelscited by 7
- 2023MOKA: Moral Knowledge Augmentation for Moral Event Extractioncited by 7
12 most cited of 23 All 23 (JSON)
- 2025Investigating LLM Capabilities on Long Context Comprehension for Medical Question Answering21 Oct 2025
- 2025Learning Facts at Scale with Active Reading13 Aug 2025
- 2025Domain Adaptation for Japanese Sentence Embeddings with Contrastive Learning based on Synthetic Sentence Generation12 Mar 2025
- 2024Benchmarking Large Language Models on Answering and Explaining Challenging Medical Questions28 Feb 2024
- 2024EHRNoteQA: An LLM Benchmark for Real-World Clinical Practice Using Discharge Summaries25 Feb 2024
- 2024Dynamic Q&A of Clinical Documents with Large Language Models19 Jan 2024
- 2023XAIQA: Explainer-Based Data Augmentation for Extractive Question Answering6 Dec 2023
- 2023MOKA: Moral Knowledge Augmentation for Moral Event Extraction16 Nov 2023
- 2023Question Answering for Electronic Health Records: A Scoping Review of datasets and models12 Oct 2023
- 2023Task-Adaptive Tokenization: Enhancing Long-Form Text Generation Efficacy in Mental Health and Beyond9 Oct 2023
- 2023MedAlign: A Clinician-Generated Dataset for Instruction Following with Electronic Medical Records27 Aug 2023
- 2023PaniniQA: Enhancing Patient Education Through Interactive Question Answering7 Aug 2023
12 newest of 23 All 23 (JSON)