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CliniQG4QA: Generating Diverse Questions for Domain Adaptation of Clinical Question Answering

arXiv 2010.16021 ↗First posted 30 Oct 2020cs.CLcited by 26

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Abstract (arXiv)

Clinical question answering (QA) aims to automatically answer questions from medical professionals based on clinical texts. Studies show that neural QA models trained on one corpus may not generalize well to new clinical texts from a different institute or a different patient group, where large-scale QA pairs are not readily available for model retraining. To address this challenge, we propose a simple yet effective framework, CliniQG4QA, which leverages question generation (QG) to synthesize QA pairs on new clinical contexts and boosts QA models without requiring manual annotations. In order to generate diverse types of questions that are essential for training QA models, we further introduce a seq2seq-based question phrase prediction (QPP) module that can be used together with most existing QG models to diversify the generation. Our comprehensive experiment results show that the QA corpus generated by our framework can improve QA models on the new contexts (up to 8% absolute gain in terms of Exact Match), and that the QPP module plays a crucial role in achieving the gain.

Key facts. Cited by 26 papers in the map (data through 7 Oct 2026). First posted on arXiv 30 Oct 2020.

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Citing papers per year: 2021: 3; 2022: 7; 2023: 7; 2024: 3; 2025: 6.

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  1. 2024Benchmarking Large Language Models on Answering and Explaining Challenging Medical Questionscited by 106
  2. 2023MedAlign: A Clinician-Generated Dataset for Instruction Following with Electronic Medical Recordscited by 54
  3. 2021Biomedical Question Answering: A Survey of Approaches and Challengescited by 46
  4. 2024EHRNoteQA: An LLM Benchmark for Real-World Clinical Practice Using Discharge Summariescited by 33
  5. 2023Task-Adaptive Tokenization: Enhancing Long-Form Text Generation Efficacy in Mental Health and Beyondcited by 22
  6. 2023PaniniQA: Enhancing Patient Education Through Interactive Question Answeringcited by 21
  7. 2022Question Generation for Reading Comprehension Assessment by Modeling How and What to Askcited by 20
  8. 2022DrugEHRQA: A Question Answering Dataset on Structured and Unstructured Electronic Health Records For Medicine Related Queriescited by 17
  9. 2022Learning to Ask Like a Physiciancited by 16
  10. 2025Learning Facts at Scale with Active Readingcited by 11
  11. 2025Experience Retrieval-Augmentation with Electronic Health Records Enables Accurate Discharge QAcited by 9
  12. 2023Question Answering for Electronic Health Records: A Scoping Review of datasets and modelscited by 7
14 more
  1. 2023MOKA: Moral Knowledge Augmentation for Moral Event Extractioncited by 7
  2. 2022Generative Entity-to-Entity Stance Detection with Knowledge Graph Augmentationcited by 6
  3. 2025RGAR: Recurrence Generation-augmented Retrieval for Factual-aware Medical Question Answeringcited by 5
  4. 2024Dynamic Q&A of Clinical Documents with Large Language Modelscited by 4
  5. 2021Automated question generation and question answering from Turkish textscited by 3
  6. 2022BioADAPT-MRC: Adversarial Learning-based Domain Adaptation Improves Biomedical Machine Reading Comprehension Taskcited by 3
  7. 2022Source-Free Domain Adaptation for Question Answering with Masked Self-trainingcited by 3
  8. 2021Towards More Robust Natural Language Understandingcited by 2
  9. 2022QA Domain Adaptation using Hidden Space Augmentation and Self-Supervised Contrastive Adaptationcited by 2
  10. 2023JCSE: Contrastive Learning of Japanese Sentence Embeddings and Its Applicationscited by 1
  11. 2025Domain Adaptation for Japanese Sentence Embeddings with Contrastive Learning based on Synthetic Sentence Generationcited by 1
  12. 2025Domain-Specific Data Generation Framework for RAG Adaptationcited by 1
  13. 2023XAIQA: Explainer-Based Data Augmentation for Extractive Question Answeringcited by 0
  14. 2025Investigating LLM Capabilities on Long Context Comprehension for Medical Question Answeringcited by 0