Knowledge Graph-based Question Answering with Electronic Health Records
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Abstract (arXiv)
Question Answering (QA) is a widely-used framework for developing and evaluating an intelligent machine. In this light, QA on Electronic Health Records (EHR), namely EHR QA, can work as a crucial milestone towards developing an intelligent agent in healthcare. EHR data are typically stored in a relational database, which can also be converted to a directed acyclic graph, allowing two approaches for EHR QA: Table-based QA and Knowledge Graph-based QA. We hypothesize that the graph-based approach is more suitable for EHR QA as graphs can represent relations between entities and values more naturally compared to tables, which essentially require JOIN operations. In this paper, we propose a graph-based EHR QA where natural language queries are converted to SPARQL instead of SQL. To validate our hypothesis, we create four EHR QA datasets (graph-based VS table-based, and simplified database schema VS original database schema), based on a table-based dataset MIMICSQL. We test both a simple Seq2Seq model and a state-of-the-art EHR QA model on all datasets where the graph-based datasets facilitated up to 34% higher accuracy than the table-based dataset without any modification to the model architectures. Finally, all datasets are open-sourced to encourage further EHR QA research in both directions.
Key facts. Cited by 19 papers in the map (data through 7 Oct 2026). First posted on arXiv 19 Oct 2020.
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Citing papers per year: 2021: 2; 2022: 3; 2023: 4; 2024: 3; 2025: 5; 2026: 2.
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- 2021Biomedical Question Answering: A Survey of Approaches and Challengescited by 46
- 2023EHRSQL: A Practical Text-to-SQL Benchmark for Electronic Health Recordscited by 42
- 2022Graph-Text Multi-Modal Pre-training for Medical Representation Learningcited by 10
- 2024SM3-Text-to-Query: Synthetic Multi-Model Medical Text-to-Query Benchmarkcited by 10
- 2025Tabular Data Understanding with LLMs: A Survey of Recent Advances and Challengescited by 10
- 2021Question Answering for Complex Electronic Health Records Database using Unified Encoder-Decoder Architecturecited by 9
- 2023LeafAI: query generator for clinical cohort discovery rivaling a human programmercited by 8
- 2023Question Answering for Electronic Health Records: A Scoping Review of datasets and modelscited by 7
- 2024LG AI Research & KAIST at EHRSQL 2024: Self-Training Large Language Models with Pseudo-Labeled Unanswerable Questions for a Reliable Text-to-SQL System on EHRscited by 7
- 2022Uncertainty-Aware Text-to-Program for Question Answering on Structured Electronic Health Recordscited by 4
- 2025BioMol-MQA: A Multi-Modal Question Answering Dataset For LLM Reasoning Over Bio-Molecular Interactionscited by 4
- 2024FathomGPT: A Natural Language Interface for Interactively Exploring Ocean Science Datacited by 3
7 more
- 2022A Comparative Study of Question Answering over Knowledge Basescited by 2
- 2026EHRBench: An Automated and Reliable EHR-based Benchmark for Clinical Decision Making with LLMscited by 2
- 2025From EMR Data to Clinical Insight: An LLM-Driven Framework for Automated Pre-Consultation Questionnaire Generationcited by 1
- 2025HealthBranches: Synthesizing Clinically-Grounded Question Answering Datasets via Decision Pathwayscited by 1
- 2026EHRNavigator: A Multi-Agent System for Patient-Level Clinical Question Answering over Heterogeneous Electronic Health Recordscited by 1
- 2023CLIFT: Analysing Natural Distribution Shift on Question Answering Models in Clinical Domaincited by 0
- 2025SCARE: A Benchmark for SQL Correction and Question Answerability Classification for Reliable EHR Question Answeringcited by 0
- 2026EHRBench: An Automated and Reliable EHR-based Benchmark for Clinical Decision Making with LLMs28 May 2026
- 2026EHRNavigator: A Multi-Agent System for Patient-Level Clinical Question Answering over Heterogeneous Electronic Health Records15 Jan 2026
- 2025SCARE: A Benchmark for SQL Correction and Question Answerability Classification for Reliable EHR Question Answering13 Nov 2025
- 2025HealthBranches: Synthesizing Clinically-Grounded Question Answering Datasets via Decision Pathways10 Aug 2025
- 2025From EMR Data to Clinical Insight: An LLM-Driven Framework for Automated Pre-Consultation Questionnaire Generation1 Aug 2025
- 2025Tabular Data Understanding with LLMs: A Survey of Recent Advances and Challenges31 Jul 2025
- 2025BioMol-MQA: A Multi-Modal Question Answering Dataset For LLM Reasoning Over Bio-Molecular Interactions6 Jun 2025
- 2024FathomGPT: A Natural Language Interface for Interactively Exploring Ocean Science Data3 Dec 2024
- 2024SM3-Text-to-Query: Synthetic Multi-Model Medical Text-to-Query Benchmark8 Nov 2024
- 2024LG AI Research & KAIST at EHRSQL 2024: Self-Training Large Language Models with Pseudo-Labeled Unanswerable Questions for a Reliable Text-to-SQL System on EHRs18 May 2024
- 2023CLIFT: Analysing Natural Distribution Shift on Question Answering Models in Clinical Domain19 Oct 2023
- 2023Question Answering for Electronic Health Records: A Scoping Review of datasets and models12 Oct 2023
7 more
- 2023LeafAI: query generator for clinical cohort discovery rivaling a human programmer13 Apr 2023
- 2023EHRSQL: A Practical Text-to-SQL Benchmark for Electronic Health Records16 Jan 2023
- 2022A Comparative Study of Question Answering over Knowledge Bases15 Nov 2022
- 2022Graph-Text Multi-Modal Pre-training for Medical Representation Learning18 Mar 2022
- 2022Uncertainty-Aware Text-to-Program for Question Answering on Structured Electronic Health Records14 Mar 2022
- 2021Question Answering for Complex Electronic Health Records Database using Unified Encoder-Decoder Architecture14 Nov 2021
- 2021Biomedical Question Answering: A Survey of Approaches and Challenges10 Feb 2021
- 2021Biomedical Question Answering: A Survey of Approaches and Challengescited by 46
- 2023EHRSQL: A Practical Text-to-SQL Benchmark for Electronic Health Recordscited by 42
- 2022Graph-Text Multi-Modal Pre-training for Medical Representation Learningcited by 10
- 2024SM3-Text-to-Query: Synthetic Multi-Model Medical Text-to-Query Benchmarkcited by 10
- 2021Question Answering for Complex Electronic Health Records Database using Unified Encoder-Decoder Architecturecited by 9
- 2023LeafAI: query generator for clinical cohort discovery rivaling a human programmercited by 8
- 2023Question Answering for Electronic Health Records: A Scoping Review of datasets and modelscited by 7
- 2022Uncertainty-Aware Text-to-Program for Question Answering on Structured Electronic Health Recordscited by 4
- 2024FathomGPT: A Natural Language Interface for Interactively Exploring Ocean Science Datacited by 3
- 2022A Comparative Study of Question Answering over Knowledge Basescited by 2
- 2026EHRBench: An Automated and Reliable EHR-based Benchmark for Clinical Decision Making with LLMscited by 2
- 2025From EMR Data to Clinical Insight: An LLM-Driven Framework for Automated Pre-Consultation Questionnaire Generationcited by 1
12 most cited of 15 All 15 (JSON)
- 2026EHRBench: An Automated and Reliable EHR-based Benchmark for Clinical Decision Making with LLMs28 May 2026
- 2026EHRNavigator: A Multi-Agent System for Patient-Level Clinical Question Answering over Heterogeneous Electronic Health Records15 Jan 2026
- 2025SCARE: A Benchmark for SQL Correction and Question Answerability Classification for Reliable EHR Question Answering13 Nov 2025
- 2025From EMR Data to Clinical Insight: An LLM-Driven Framework for Automated Pre-Consultation Questionnaire Generation1 Aug 2025
- 2024FathomGPT: A Natural Language Interface for Interactively Exploring Ocean Science Data3 Dec 2024
- 2024SM3-Text-to-Query: Synthetic Multi-Model Medical Text-to-Query Benchmark8 Nov 2024
- 2023CLIFT: Analysing Natural Distribution Shift on Question Answering Models in Clinical Domain19 Oct 2023
- 2023Question Answering for Electronic Health Records: A Scoping Review of datasets and models12 Oct 2023
- 2023LeafAI: query generator for clinical cohort discovery rivaling a human programmer13 Apr 2023
- 2023EHRSQL: A Practical Text-to-SQL Benchmark for Electronic Health Records16 Jan 2023
- 2022A Comparative Study of Question Answering over Knowledge Bases15 Nov 2022
- 2022Graph-Text Multi-Modal Pre-training for Medical Representation Learning18 Mar 2022
12 newest of 15 All 15 (JSON)