Graph-Text Multi-Modal Pre-training for Medical Representation Learning
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Abstract (arXiv)
As the volume of Electronic Health Records (EHR) sharply grows, there has been emerging interest in learning the representation of EHR for healthcare applications. Representation learning of EHR requires appropriate modeling of the two dominant modalities in EHR: structured data and unstructured text. In this paper, we present MedGTX, a pre-trained model for multi-modal representation learning of the structured and textual EHR data. MedGTX uses a novel graph encoder to exploit the graphical nature of structured EHR data, and a text encoder to handle unstructured text, and a cross-modal encoder to learn a joint representation space. We pre-train our model through four proxy tasks on MIMIC-III, an open-source EHR data, and evaluate our model on two clinical benchmarks and three novel downstream tasks which tackle real-world problems in EHR data. The results consistently show the effectiveness of pre-training the model for joint representation of both structured and unstructured information from EHR. Given the promising performance of MedGTX, we believe this work opens a new door to jointly understanding the two fundamental modalities of EHR data.
Key facts. Cited by 10 papers in the map (data through 14 Oct 2026). Builds on 28 of its 51 references that are in the map. First posted on arXiv 18 Mar 2022.
Builds on
28 of 51 references.
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16 more
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Citing papers per year: 2022: 1; 2023: 1; 2024: 6; 2025: 2.
10 papers.
- 2024EMERGE: Enhancing Multimodal Electronic Health Records Predictive Modeling with Retrieval-Augmented Generationcited by 17
- 2024Can Graph Neural Networks Learn Language with Extremely Weak Text Supervision?cited by 13
- 2022Unsupervised pre-training of graph transformers on patient population graphscited by 9
- 2024CTPD: Cross-Modal Temporal Pattern Discovery for Enhanced Multimodal Electronic Health Records Analysiscited by 6
- 2024Bridging Stepwise Lab-Informed Pretraining and Knowledge-Guided Learning for Diagnostic Reasoningcited by 3
- 2023Multi-modal Graph Learning over UMLS Knowledge Graphscited by 2
- 2025CAST: Cross Attention based multimodal fusion of Structure and Text for materials property predictioncited by 2
- 2024From Basic to Extra Features: Hypergraph Transformer Pretrain-then-Finetuning for Balanced Clinical Predictions on EHRcited by 1
- 2024MPLite: Multi-Aspect Pretraining for Mining Clinical Health Recordscited by 1
- 2025Patient-level Information Extraction by Consistent Integration of Textual and Tabular Evidence with Bayesian Networkscited by 0
- 2025Patient-level Information Extraction by Consistent Integration of Textual and Tabular Evidence with Bayesian Networks21 Nov 2025
- 2025CAST: Cross Attention based multimodal fusion of Structure and Text for materials property prediction6 Feb 2025
- 2024Can Graph Neural Networks Learn Language with Extremely Weak Text Supervision?11 Dec 2024
- 2024MPLite: Multi-Aspect Pretraining for Mining Clinical Health Records17 Nov 2024
- 2024CTPD: Cross-Modal Temporal Pattern Discovery for Enhanced Multimodal Electronic Health Records Analysis1 Nov 2024
- 2024Bridging Stepwise Lab-Informed Pretraining and Knowledge-Guided Learning for Diagnostic Reasoning25 Oct 2024
- 2024From Basic to Extra Features: Hypergraph Transformer Pretrain-then-Finetuning for Balanced Clinical Predictions on EHR9 Jun 2024
- 2024EMERGE: Enhancing Multimodal Electronic Health Records Predictive Modeling with Retrieval-Augmented Generation27 May 2024
- 2023Multi-modal Graph Learning over UMLS Knowledge Graphs10 Jul 2023
- 2022Unsupervised pre-training of graph transformers on patient population graphs21 Jul 2022