Deep Active Learning for Joint Classification & Segmentation with Weak Annotator
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Abstract (arXiv)
CNN visualization and interpretation methods, like class-activation maps (CAMs), are typically used to highlight the image regions linked to class predictions. These models allow to simultaneously classify images and extract class-dependent saliency maps, without the need for costly pixel-level annotations. However, they typically yield segmentations with high false-positive rates and, therefore, coarse visualisations, more so when processing challenging images, as encountered in histology. To mitigate this issue, we propose an active learning (AL) framework, which progressively integrates pixel-level annotations during training. Given training data with global image-level labels, our deep weakly-supervised learning model jointly performs supervised image-level classification and active learning for segmentation, integrating pixel annotations by an oracle. Unlike standard AL methods that focus on sample selection, we also leverage large numbers of unlabeled images via pseudo-segmentations (i.e., self-learning at the pixel level), and integrate them with the oracle-annotated samples during training. We report extensive experiments over two challenging benchmarks -- high-resolution medical images (histology GlaS data for colon cancer) and natural images (CUB-200-2011 for bird species). Our results indicate that, by simply using random sample selection, the proposed approach can significantly outperform state-of the-art CAMs and AL methods, with an identical oracle-supervision budget. Our code is publicly available.
Key facts. Cited by 16 papers in the map (data through 7 Oct 2026). First posted on arXiv 10 Oct 2020.
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Citing papers per year: 2021: 7; 2022: 2; 2023: 2; 2024: 4; 2025: 0; 2026: 1.
16 papers.
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- 2021CoNeRF: Controllable Neural Radiance Fieldscited by 65
- 2021Multi-Layer Pseudo-Supervision for Histopathology Tissue Semantic Segmentation using Patch-level Classification Labelscited by 43
- 2022WSSS4LUAD: Grand Challenge on Weakly-supervised Tissue Semantic Segmentation for Lung Adenocarcinomacited by 32
- 2021F-CAM: Full Resolution Class Activation Maps via Guided Parametric Upscalingcited by 26
- 2021Medical Image Segmentation with Limited Supervision: A Review of Deep Network Modelscited by 21
- 2023Label-Efficient Deep Learning in Medical Image Analysis: Challenges and Future Directionscited by 14
- 2021Weak Adaptation Learning -- Addressing Cross-domain Data Insufficiency with Weak Annotatorcited by 8
- 2022Negative Evidence Matters in Interpretable Histology Image Classificationcited by 8
- 2021Reducing Annotating Load: Active Learning with Synthetic Images in Surgical Instrument Segmentationcited by 6
- 2024Edge-guided and Class-balanced Active Learning for Semantic Segmentation of Aerial Imagescited by 4
- 2021Practical Active Learning with Model Selection for Small Datacited by 2
- 2023Active Learning for Fine-Grained Sketch-Based Image Retrievalcited by 2
4 more
- 2024ProtoAL: Interpretable Deep Active Learning with prototypes for medical imagingcited by 2
- 2024Advancing Histopathology with Deep Learning Under Data Scarcity: A Decade in Reviewcited by 1
- 2024Foundation Model Makes Clustering A Better Initialization For Cold-Start Active Learningcited by 0
- 2026iSAGE: A Human-in-the-Loop Framework for Remote Sensing Semantic Segmentation via Sparse Point Supervisioncited by 0
- 2026iSAGE: A Human-in-the-Loop Framework for Remote Sensing Semantic Segmentation via Sparse Point Supervision8 Jun 2026
- 2024Advancing Histopathology with Deep Learning Under Data Scarcity: A Decade in Review18 Oct 2024
- 2024Edge-guided and Class-balanced Active Learning for Semantic Segmentation of Aerial Images28 May 2024
- 2024ProtoAL: Interpretable Deep Active Learning with prototypes for medical imaging6 Apr 2024
- 2024Foundation Model Makes Clustering A Better Initialization For Cold-Start Active Learning4 Feb 2024
- 2023Active Learning for Fine-Grained Sketch-Based Image Retrieval15 Sep 2023
- 2023Label-Efficient Deep Learning in Medical Image Analysis: Challenges and Future Directions22 Mar 2023
- 2022WSSS4LUAD: Grand Challenge on Weakly-supervised Tissue Semantic Segmentation for Lung Adenocarcinoma13 Apr 2022
- 2022Negative Evidence Matters in Interpretable Histology Image Classification7 Jan 2022
- 2021Practical Active Learning with Model Selection for Small Data21 Dec 2021
- 2021CoNeRF: Controllable Neural Radiance Fields3 Dec 2021
- 2021Multi-Layer Pseudo-Supervision for Histopathology Tissue Semantic Segmentation using Patch-level Classification Labels14 Oct 2021
4 more
- 2021F-CAM: Full Resolution Class Activation Maps via Guided Parametric Upscaling15 Sep 2021
- 2021Reducing Annotating Load: Active Learning with Synthetic Images in Surgical Instrument Segmentation7 Aug 2021
- 2021Medical Image Segmentation with Limited Supervision: A Review of Deep Network Models28 Feb 2021
- 2021Weak Adaptation Learning -- Addressing Cross-domain Data Insufficiency with Weak Annotator15 Feb 2021
- 2021CoNeRF: Controllable Neural Radiance Fieldscited by 65
- 2021Multi-Layer Pseudo-Supervision for Histopathology Tissue Semantic Segmentation using Patch-level Classification Labelscited by 43
- 2022WSSS4LUAD: Grand Challenge on Weakly-supervised Tissue Semantic Segmentation for Lung Adenocarcinomacited by 32
- 2021F-CAM: Full Resolution Class Activation Maps via Guided Parametric Upscalingcited by 26
- 2021Medical Image Segmentation with Limited Supervision: A Review of Deep Network Modelscited by 21
- 2023Label-Efficient Deep Learning in Medical Image Analysis: Challenges and Future Directionscited by 14
- 2021Weak Adaptation Learning -- Addressing Cross-domain Data Insufficiency with Weak Annotatorcited by 8
- 2022Negative Evidence Matters in Interpretable Histology Image Classificationcited by 8
- 2021Reducing Annotating Load: Active Learning with Synthetic Images in Surgical Instrument Segmentationcited by 6
- 2024Edge-guided and Class-balanced Active Learning for Semantic Segmentation of Aerial Imagescited by 4
- 2021Practical Active Learning with Model Selection for Small Datacited by 2
- 2023Active Learning for Fine-Grained Sketch-Based Image Retrievalcited by 2
12 most cited of 16 All 16 (JSON)
- 2026iSAGE: A Human-in-the-Loop Framework for Remote Sensing Semantic Segmentation via Sparse Point Supervision8 Jun 2026
- 2024Advancing Histopathology with Deep Learning Under Data Scarcity: A Decade in Review18 Oct 2024
- 2024Edge-guided and Class-balanced Active Learning for Semantic Segmentation of Aerial Images28 May 2024
- 2024ProtoAL: Interpretable Deep Active Learning with prototypes for medical imaging6 Apr 2024
- 2024Foundation Model Makes Clustering A Better Initialization For Cold-Start Active Learning4 Feb 2024
- 2023Active Learning for Fine-Grained Sketch-Based Image Retrieval15 Sep 2023
- 2023Label-Efficient Deep Learning in Medical Image Analysis: Challenges and Future Directions22 Mar 2023
- 2022WSSS4LUAD: Grand Challenge on Weakly-supervised Tissue Semantic Segmentation for Lung Adenocarcinoma13 Apr 2022
- 2022Negative Evidence Matters in Interpretable Histology Image Classification7 Jan 2022
- 2021Practical Active Learning with Model Selection for Small Data21 Dec 2021
- 2021CoNeRF: Controllable Neural Radiance Fields3 Dec 2021
- 2021Multi-Layer Pseudo-Supervision for Histopathology Tissue Semantic Segmentation using Patch-level Classification Labels14 Oct 2021
12 newest of 16 All 16 (JSON)