Unsupervised Medical Image Translation Using Cycle-MedGAN
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Abstract (arXiv)
Image-to-image translation is a new field in computer vision with multiple potential applications in the medical domain. However, for supervised image translation frameworks, co-registered datasets, paired in a pixel-wise sense, are required. This is often difficult to acquire in realistic medical scenarios. On the other hand, unsupervised translation frameworks often result in blurred translated images with unrealistic details. In this work, we propose a new unsupervised translation framework which is titled Cycle-MedGAN. The proposed framework utilizes new non-adversarial cycle losses which direct the framework to minimize the textural and perceptual discrepancies in the translated images. Qualitative and quantitative comparisons against other unsupervised translation approaches demonstrate the performance of the proposed framework for PET-CT translation and MR motion correction.
Key facts. Cited by 44 papers in the map (data through 7 Oct 2026). First posted on arXiv 8 Mar 2019.
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Citing papers per year: 2021: 10; 2022: 11; 2023: 9; 2024: 9; 2025: 5.
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- 2021Image-to-Image Translation: Methods and Applicationscited by 116
- 2021Anomaly Detection in Medical Imaging -- A Mini Reviewcited by 44
- 2023Echo from noise: synthetic ultrasound image generation using diffusion models for real image segmentationcited by 33
- 2021Conditional Frechet Inception Distancecited by 16
- 2021Uncertainty-Guided Progressive GANs for Medical Image Translationcited by 16
- 2021CyTran: A Cycle-Consistent Transformer with Multi-Level Consistency for Non-Contrast to Contrast CT Translationcited by 15
- 2023MRI Reconstruction with Side Information using Diffusion Modelscited by 15
- 2022Assessing the ability of generative adversarial networks to learn canonical medical image statisticscited by 11
- 2021Is Image-to-Image Translation the Panacea for Multimodal Image Registration? A Comparative Studycited by 9
- 2023Cross Attention Transformers for Multi-modal Unsupervised Whole-Body PET Anomaly Detectioncited by 7
- 2021Simultaneous super-resolution and motion artifact removal in diffusion-weighted MRI using unsupervised deep learningcited by 6
- 2021Bridging the gap between paired and unpaired medical image translationcited by 6
32 more
- 2022Anatomically constrained CT image translation for heterogeneous blood vessel segmentationcited by 6
- 2021Multi-Texture GAN: Exploring the Multi-Scale Texture Translation for Brain MR Imagescited by 4
- 2022Deep neural networks can stably solve high-dimensional, noisy, non-linear inverse problemscited by 3
- 2022ChrSNet: Chromosome Straightening using Self-attention Guided Networkscited by 3
- 2025DIMA: DIffusing Motion Artifacts for unsupervised correction in brain MRI imagescited by 3
- 2021ASL to PET Translation by a Semi-supervised Residual-based Attention-guided Convolutional Neural Networkcited by 2
- 2022Synthetic PET via Domain Translation of 3D MRIcited by 2
- 2022Brain MRI-to-PET Synthesis using 3D Convolutional Attention Networkscited by 2
- 2024ContourDiff: Unpaired Medical Image Translation with Structural Consistencycited by 2
- 2024Anatomical Conditioning for Contrastive Unpaired Image-to-Image Translation of Optical Coherence Tomography Imagescited by 2
- 2024Cyclic 2.5D Perceptual Loss for Cross-Modal 3D Medical Image Synthesis: T1w MRI to Tau PETcited by 2
- 2024CAS-GAN for Contrast-free Angiography Synthesiscited by 2
- 2022Multi-task Deep Learning for Cerebrovascular Disease Classification and MRI-to-PET Translationcited by 1
- 2023Counterfactual Explanation and Instance-Generation using Cycle-Consistent Generative Adversarial Networkscited by 1
- 2023PaCaNet: A Study on CycleGAN with Transfer Learning for Diversifying Fused Chinese Painting and Calligraphycited by 1
- 2024Cross-Modality Translation with Generative Adversarial Networks to Unveil Alzheimer's Disease Biomarkerscited by 1
- 2024Efficient Semantic Diffusion Architectures for Model Training on Synthetic Echocardiogramscited by 1
- 2024Enhancing frozen histological section images using permanent-section-guided deep learning with nuclei attentioncited by 1
- 2025Schr"odinger Diffusion Driven Signal Recovery in 3T BOLD fMRI Using Unmatched 7T Observationscited by 1
- 2025GAN-based synthetic FDG PET images from T1 brain MRI can serve to improve performance of deep unsupervised anomaly detection modelscited by 1
- 2022Deep Learning-Assisted Co-registration of Full-Spectral Autofluorescence Lifetime Microscopic Images with H&E-Stained Histology Imagescited by 0
- 2022MDT-Net: Multi-domain Transfer by Perceptual Supervision for Unpaired Images in OCT Scancited by 0
- 2022Structure Unbiased Adversarial Model for Medical Image Segmentationcited by 0
- 2022Disentangled Uncertainty and Out of Distribution Detection in Medical Generative Modelscited by 0
- 2023Exploring the Power of Generative Deep Learning for Image-to-Image Translation and MRI Reconstruction: A Cross-Domain Reviewcited by 0
- 2023XVertNet: Unsupervised Contrast Enhancement of Vertebral Structures with Dynamic Self-Tuning Guidance and Multi-Stage Analysiscited by 0
- 2023Domain Transfer Through Image-to-Image Translation for Uncertainty-Aware Prostate Cancer Classificationcited by 0
- 2023A Strictly Bounded Deep Network for Unpaired Cyclic Translation of Medical Imagescited by 0
- 2024Leveraging Multimodal CycleGAN for the Generation of Anatomically Accurate Synthetic CT Scans from MRIscited by 0
- 2024DeepSPV: A Deep Learning Pipeline for 3D Spleen Volume Estimation from 2D Ultrasound Imagescited by 0
- 2025Structure-Accurate Medical Image Translation via Dynamic Frequency Balance and Knowledge Guidancecited by 0
- 2025Diffusion-based translation between unpaired spontaneous premature neonatal EEG and fetal MEGcited by 0
- 2025Diffusion-based translation between unpaired spontaneous premature neonatal EEG and fetal MEG16 Jul 2025
- 2025GAN-based synthetic FDG PET images from T1 brain MRI can serve to improve performance of deep unsupervised anomaly detection models12 May 2025
- 2025Structure-Accurate Medical Image Translation via Dynamic Frequency Balance and Knowledge Guidance13 Apr 2025
- 2025DIMA: DIffusing Motion Artifacts for unsupervised correction in brain MRI images9 Apr 2025
- 2025Schr"odinger Diffusion Driven Signal Recovery in 3T BOLD fMRI Using Unmatched 7T Observations1 Apr 2025
- 2024DeepSPV: A Deep Learning Pipeline for 3D Spleen Volume Estimation from 2D Ultrasound Images17 Nov 2024
- 2024Enhancing frozen histological section images using permanent-section-guided deep learning with nuclei attention10 Nov 2024
- 2024CAS-GAN for Contrast-free Angiography Synthesis11 Oct 2024
- 2024Efficient Semantic Diffusion Architectures for Model Training on Synthetic Echocardiograms28 Sep 2024
- 2024Leveraging Multimodal CycleGAN for the Generation of Anatomically Accurate Synthetic CT Scans from MRIs15 Jul 2024
- 2024Cyclic 2.5D Perceptual Loss for Cross-Modal 3D Medical Image Synthesis: T1w MRI to Tau PET18 Jun 2024
- 2024Cross-Modality Translation with Generative Adversarial Networks to Unveil Alzheimer's Disease Biomarkers8 May 2024
32 more
- 2024Anatomical Conditioning for Contrastive Unpaired Image-to-Image Translation of Optical Coherence Tomography Images8 Apr 2024
- 2024ContourDiff: Unpaired Medical Image Translation with Structural Consistency16 Mar 2024
- 2023A Strictly Bounded Deep Network for Unpaired Cyclic Translation of Medical Images4 Nov 2023
- 2023Domain Transfer Through Image-to-Image Translation for Uncertainty-Aware Prostate Cancer Classification2 Jul 2023
- 2023XVertNet: Unsupervised Contrast Enhancement of Vertebral Structures with Dynamic Self-Tuning Guidance and Multi-Stage Analysis6 Jun 2023
- 2023Echo from noise: synthetic ultrasound image generation using diffusion models for real image segmentation9 May 2023
- 2023Cross Attention Transformers for Multi-modal Unsupervised Whole-Body PET Anomaly Detection14 Apr 2023
- 2023MRI Reconstruction with Side Information using Diffusion Models26 Mar 2023
- 2023Exploring the Power of Generative Deep Learning for Image-to-Image Translation and MRI Reconstruction: A Cross-Domain Review16 Mar 2023
- 2023PaCaNet: A Study on CycleGAN with Transfer Learning for Diversifying Fused Chinese Painting and Calligraphy30 Jan 2023
- 2023Counterfactual Explanation and Instance-Generation using Cycle-Consistent Generative Adversarial Networks21 Jan 2023
- 2022Brain MRI-to-PET Synthesis using 3D Convolutional Attention Networks22 Nov 2022
- 2022Disentangled Uncertainty and Out of Distribution Detection in Medical Generative Models11 Nov 2022
- 2022Anatomically constrained CT image translation for heterogeneous blood vessel segmentation4 Oct 2022
- 2022ChrSNet: Chromosome Straightening using Self-attention Guided Networks1 Jul 2022
- 2022Synthetic PET via Domain Translation of 3D MRI11 Jun 2022
- 2022Deep neural networks can stably solve high-dimensional, noisy, non-linear inverse problems2 Jun 2022
- 2022Structure Unbiased Adversarial Model for Medical Image Segmentation25 May 2022
- 2022Assessing the ability of generative adversarial networks to learn canonical medical image statistics26 Apr 2022
- 2022MDT-Net: Multi-domain Transfer by Perceptual Supervision for Unpaired Images in OCT Scan12 Mar 2022
- 2022Deep Learning-Assisted Co-registration of Full-Spectral Autofluorescence Lifetime Microscopic Images with H&E-Stained Histology Images15 Feb 2022
- 2022Multi-task Deep Learning for Cerebrovascular Disease Classification and MRI-to-PET Translation12 Feb 2022
- 2021Bridging the gap between paired and unpaired medical image translation15 Oct 2021
- 2021CyTran: A Cycle-Consistent Transformer with Multi-Level Consistency for Non-Contrast to Contrast CT Translation12 Oct 2021
- 2021Anomaly Detection in Medical Imaging -- A Mini Review25 Aug 2021
- 2021Uncertainty-Guided Progressive GANs for Medical Image Translation29 Jun 2021
- 2021Simultaneous super-resolution and motion artifact removal in diffusion-weighted MRI using unsupervised deep learning1 May 2021
- 2021Is Image-to-Image Translation the Panacea for Multimodal Image Registration? A Comparative Study30 Mar 2021
- 2021Conditional Frechet Inception Distance21 Mar 2021
- 2021ASL to PET Translation by a Semi-supervised Residual-based Attention-guided Convolutional Neural Network8 Mar 2021
- 2021Multi-Texture GAN: Exploring the Multi-Scale Texture Translation for Brain MR Images14 Feb 2021
- 2021Image-to-Image Translation: Methods and Applications21 Jan 2021
- 2023Echo from noise: synthetic ultrasound image generation using diffusion models for real image segmentationcited by 33
- 2023MRI Reconstruction with Side Information using Diffusion Modelscited by 15
- 2025DIMA: DIffusing Motion Artifacts for unsupervised correction in brain MRI imagescited by 3
- 2024ContourDiff: Unpaired Medical Image Translation with Structural Consistencycited by 2
- 2024Efficient Semantic Diffusion Architectures for Model Training on Synthetic Echocardiogramscited by 1
- 2025DIMA: DIffusing Motion Artifacts for unsupervised correction in brain MRI images9 Apr 2025
- 2024Efficient Semantic Diffusion Architectures for Model Training on Synthetic Echocardiograms28 Sep 2024
- 2024ContourDiff: Unpaired Medical Image Translation with Structural Consistency16 Mar 2024
- 2023Echo from noise: synthetic ultrasound image generation using diffusion models for real image segmentation9 May 2023
- 2023MRI Reconstruction with Side Information using Diffusion Models26 Mar 2023
- 2021Image-to-Image Translation: Methods and Applicationscited by 116
- 2021Anomaly Detection in Medical Imaging -- A Mini Reviewcited by 44
- 2021Conditional Frechet Inception Distancecited by 16
- 2021Uncertainty-Guided Progressive GANs for Medical Image Translationcited by 16
- 2021CyTran: A Cycle-Consistent Transformer with Multi-Level Consistency for Non-Contrast to Contrast CT Translationcited by 15
- 2022Assessing the ability of generative adversarial networks to learn canonical medical image statisticscited by 11
- 2021Is Image-to-Image Translation the Panacea for Multimodal Image Registration? A Comparative Studycited by 9
- 2023Cross Attention Transformers for Multi-modal Unsupervised Whole-Body PET Anomaly Detectioncited by 7
- 2021Simultaneous super-resolution and motion artifact removal in diffusion-weighted MRI using unsupervised deep learningcited by 6
- 2021Bridging the gap between paired and unpaired medical image translationcited by 6
- 2022Anatomically constrained CT image translation for heterogeneous blood vessel segmentationcited by 6
- 2021Multi-Texture GAN: Exploring the Multi-Scale Texture Translation for Brain MR Imagescited by 4
12 most cited of 39 All 39 (JSON)
- 2025Diffusion-based translation between unpaired spontaneous premature neonatal EEG and fetal MEG16 Jul 2025
- 2025GAN-based synthetic FDG PET images from T1 brain MRI can serve to improve performance of deep unsupervised anomaly detection models12 May 2025
- 2025Structure-Accurate Medical Image Translation via Dynamic Frequency Balance and Knowledge Guidance13 Apr 2025
- 2025Schr"odinger Diffusion Driven Signal Recovery in 3T BOLD fMRI Using Unmatched 7T Observations1 Apr 2025
- 2024DeepSPV: A Deep Learning Pipeline for 3D Spleen Volume Estimation from 2D Ultrasound Images17 Nov 2024
- 2024Enhancing frozen histological section images using permanent-section-guided deep learning with nuclei attention10 Nov 2024
- 2024CAS-GAN for Contrast-free Angiography Synthesis11 Oct 2024
- 2024Leveraging Multimodal CycleGAN for the Generation of Anatomically Accurate Synthetic CT Scans from MRIs15 Jul 2024
- 2024Cyclic 2.5D Perceptual Loss for Cross-Modal 3D Medical Image Synthesis: T1w MRI to Tau PET18 Jun 2024
- 2024Cross-Modality Translation with Generative Adversarial Networks to Unveil Alzheimer's Disease Biomarkers8 May 2024
- 2024Anatomical Conditioning for Contrastive Unpaired Image-to-Image Translation of Optical Coherence Tomography Images8 Apr 2024
- 2023A Strictly Bounded Deep Network for Unpaired Cyclic Translation of Medical Images4 Nov 2023
12 newest of 39 All 39 (JSON)