mlsanityData to 14 Oct 2026

Are We Measuring Scientific Intelligence? Rethinking the Evaluation of AI Scientists

arXiv 2610.04915 ↗First posted 4 Oct 2026cs.AIcited by 0

New in LLM reasoning; no direction yet. LLM reasoning

Abstract (arXiv)

AI agents can now carry out data-driven scientific analyses end to end, and benchmarks assess them by giving an agent a question and a dataset and scoring its final answer against a fixed key. These benchmarks assume that a correct answer was derived from the supplied data, a property we call evidence grounding. However, an agent can also reach the key from prior knowledge or by ruling out the other options, and a score based on a single run cannot tell these cases apart. We show how to test this assumption and find that it often fails. For each question, we build versions of its data files in which the evidence for the answer is left intact, withdrawn or reversed, check each edit with a pre-registered reference statistic, and run the same agent on every version. We then measure evidence-grounded accuracy, which credits a correct answer only if the agent also responds when the evidence is withdrawn and follows it when it is reversed. We evaluate three agent scaffolds and five models on 18 single-cell questions from BAISBench and four synthetic problems from GeneBench-Pro. On the single-cell questions, the Claude agents are 95% accurate and answer 83% correctly without any data, but their evidence-grounded accuracy is only 41%. Hiding gene names raises the share of runs that follow reversed evidence from 58% to 93% on ten gene tasks, suggesting that prior knowledge competes with the supplied data. The benchmark score and LLM judges can also reward answers that ignore the changed evidence. Measuring scientific intelligence rather than recall therefore requires checking whether answers follow the evidence and whether scores reward them for it.

Key facts. No citing papers in the map yet (data through 14 Oct 2026). Builds on 40 of its 49 references that are in the map. First posted on arXiv 4 Oct 2026.

Builds on

40 of 49 references.

References · 40

  1. 2020Measuring Massive Multitask Language Understandingcited by 7,963
  2. 2023Let's Verify Step by Stepcited by 3,789
  3. 2023GPQA: A Graduate-Level Google-Proof Q&A Benchmarkcited by 2,879
  4. 2023Language Models Don't Always Say What They Think: Unfaithful Explanations in Chain-of-Thought Promptingcited by 1,122
  5. 2024The AI Scientist: Towards Fully Automated Open-Ended Scientific Discoverycited by 1,071
  6. 2020Beyond Accuracy: Behavioral Testing of NLP models with CheckListcited by 1,006
  7. 2024Are We on the Right Way for Evaluating Large Vision-Language Models?cited by 914
  8. 2018Annotation Artifacts in Natural Language Inference Datacited by 671
  9. 2024MLE-bench: Evaluating Machine Learning Agents on Machine Learning Engineeringcited by 469
  10. 2019Learning the Difference that Makes a Difference with Counterfactually-Augmented Datacited by 439
  11. 2025Reasoning Models Don't Always Say What They Thinkcited by 415
  12. 2025Accelerating scientific discovery with Co-Scientistcited by 401
28 more
  1. 2025Monitoring Reasoning Models for Misbehavior and the Risks of Promoting Obfuscationcited by 384
  2. 2021Entity-Based Knowledge Conflicts in Question Answeringcited by 356
  3. 2023Adaptive Chameleon or Stubborn Sloth: Revealing the Behavior of Large Language Models in Knowledge Conflictscited by 341
  4. 2025PaperBench: Evaluating AI's Ability to Replicate AI Researchcited by 321
  5. 2018Hypothesis Only Baselines in Natural Language Inferencecited by 295
  6. 2024Agent-as-a-Judge: Evaluate Agents with Agentscited by 238
  7. 2024ScienceAgentBench: Toward Rigorous Assessment of Language Agents for Data-Driven Scientific Discoverycited by 235
  8. 2024SciCode: A Research Coding Benchmark Curated by Scientistscited by 178
  9. 2024LAB-Bench: Measuring Capabilities of Language Models for Biology Researchcited by 156
  10. 2024When Benchmarks are Targets: Revealing the Sensitivity of Large Language Model Leaderboardscited by 137
  11. 2024CORE-Bench: Fostering the Credibility of Published Research Through a Computational Reproducibility Agent Benchmarkcited by 123
  12. 2025Measuring what Matters: Construct Validity in Large Language Model Benchmarkscited by 119
  13. 2023SciEval: A Multi-Level Large Language Model Evaluation Benchmark for Scientific Researchcited by 115
  14. 2024DiscoveryBench: Towards Data-Driven Discovery with Large Language Modelscited by 109
  15. 2025AgentRewardBench: Evaluating Automatic Evaluations of Web Agent Trajectoriescited by 108
  16. 2025BixBench: a Comprehensive Benchmark for LLM-based Agents in Computational Biologycited by 89
  17. 2018How Much Reading Does Reading Comprehension Require? A Critical Investigation of Popular Benchmarkscited by 88
  18. 2024BLADE: Benchmarking Language Model Agents for Data-Driven Sciencecited by 77
  19. 2024Artifacts or Abduction: How Do LLMs Answer Multiple-Choice Questions Without the Question?cited by 71
  20. 2025ImpossibleBench: Measuring LLMs' Propensity of Exploiting Test Casescited by 65
  21. 2025R&D-Agent: An LLM-Agent Framework Towards Autonomous Data Sciencecited by 41
  22. 2026HeurekaBench: A Benchmarking Framework for AI Co-scientistcited by 12
  23. 2025Benchmarking AI scientists for omics data driven biological discoverycited by 7
  24. 2026Beyond Accuracy: Evaluating Visual Grounding In Multimodal Medical Reasoningcited by 7
  25. 2026BixBench3: Benchmarking AI agents on research-study-scale computational biology taskscited by 5
  26. 2026scBench: Evaluating AI Agents on Single-Cell RNA-seq Analysiscited by 2
  27. 2026Right Answer, Wrong Method: Shortcut Hacking Misleads the Evaluation of LLM Reasoning on Frontier Science Benchmarkscited by 2
  28. 2026scBench-Long: Verifiable Benchmarking of Long-Horizon Single-Cell Biologycited by 1

Built on by

Not cited yet.

Similar, not cited

Close in wording, no citation either way

  1. 2026Can AI Agents Synthesize Scientific Conclusions?
  2. 2026AI scientists produce results without reasoning scientifically
  3. 2026TruthInsightBench: An Evidence-Grounded Benchmark for Automated Evaluation of Open-Ended Scientific Discovery Agents
  4. 2026Skill-based Agentic Evaluation for Real-time Data Science Tasks
  5. 2026K-Bench: measuring model performance on real scientific agent requests
  6. 2026Benchmarking AI Agents for Addressing Scientific Challenges Across Scales
  7. 2026AgentIdeaBench: Benchmarking Scientific Ideation in the Agent Era
  8. 2026Sci-MMR: Benchmarking Multi-Step Evidence-Grounded Scientific Reasoning in Multimodal Agents