mlsanityData to 14 Oct 2026

Counterfactual Auditing of Bias in Open-Source Large Language Models for Clinical Triage

arXiv 2610.01963 ↗First posted 1 Oct 2026cs.AI cs.CL cs.LGcited by 0

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Abstract (arXiv)

Emergency department (ED) triage is a high-stakes prioritization task in which demographic, socioeconomic, and system-context information may improperly influence acuity assignment. Although open-source large language models (LLMs) are increasingly considered for local and privacy-preserving clinical decision support, it remains unclear how counterfactual bias varies across model families, sizes, medical-domain models, and domain-adapted models. We present a comparative counterfactual audit of ten open-source LLMs for pediatric Emergency Severity Index (ESI) prediction. Starting from real and handbook-style clinical vignettes, we construct paired counterfactual variants that change only one injected demographic, socioeconomic, healthcare-access, behavioral, social, or system-context variable while holding the clinical presentation fixed. Models include Qwen2.5-7B, Qwen2.5-14B-Instruct, a QLoRA fine-tuned Qwen2.5-7B, MedGemma variants, MedLLaMA2-7B, GPT-OSS-20B, and GPT-OSS-120B. We measure any counterfactual shift, undertriage, overtriage, shifts greater than one ESI level, mean shift, and mean absolute shift. Counterfactual sensitivity varied substantially and did not consistently decrease with larger model size or medical-domain pretraining. The fine-tuned Qwen2.5-7B showed the lowest overall sensitivity, with a 5.27% any-shift rate and mean absolute shift of 0.0534, versus 16.02% and 0.1706 for the base model. Several larger or medical-domain models showed more significant shifts. Stratified and correlation analyses further revealed clinically important directionality and shared failure patterns hidden by aggregate rates. These findings support counterfactual auditing as a lightweight, clinically interpretable framework for comparing fairness risks in open-source LLMs before clinical deployment.

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References · 11

  1. 2021LoRA: Low-Rank Adaptation of Large Language Modelscited by 14,380
  2. 2024Qwen2.5 Technical Reportcited by 4,942
  3. 2023QLoRA: Efficient Finetuning of Quantized LLMscited by 3,418
  4. 2016Equality of Opportunity in Supervised Learningcited by 2,007
  5. 2025gpt-oss-120b & gpt-oss-20b Model Cardcited by 1,386
  6. 2017Counterfactual Fairnesscited by 804
  7. 2025MedGemma Technical Reportcited by 436
  8. 2024A Toolbox for Surfacing Health Equity Harms and Biases in Large Language Modelscited by 45
  9. 2024Mitigating the Risk of Health Inequity Exacerbated by Large Language Modelscited by 21
  10. 2025From Promising Capability to Pervasive Bias: Assessing Large Language Models for Emergency Department Triagecited by 5
  11. 2026Domain-Adapted Small Language Models for Reliable Clinical Triagecited by 1

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