Beyond Demographic Balance: Multi-Metric and Intersectional Evaluation of Fairness in MIMIC-IV Mortality Prediction
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Abstract (arXiv)
Fairness conclusions in clinical prediction can depend strongly on both the metrics reported and the demographic resolution at which performance is evaluated. We revisit these evaluation choices for ICU mortality prediction on MIMIC-IV, comparing predictive-utility and subgroup-error metrics across several fairness interventions. As a complementary case study, we introduce a lightweight adaptation strategy that jointly balances ethnicity--gender--insurance representation without conditioning on mortality outcomes, allowing demographic representation balancing to be examined separately from outcome-conditioned or direct error-rate interventions. We evaluate its behavior at both marginal and corresponding three-way intersectional subgroup levels, while accounting for the statistical support of finer-grained estimates. The results show that interventions can receive substantially different assessments across accuracy/AUROC, sensitivity, and false-positive rate, and that marginal demographic summaries can conceal heterogeneous error profiles within their constituent intersections, including among larger subgroups. These findings highlight the importance of evaluating fairness interventions at both complementary metric and subgroup resolutions, while accounting for the intervention target and the reliability of subgroup estimates.
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References · 8
- 2016Equality of Opportunity in Supervised Learningcited by 2,000
- 2016Fair prediction with disparate impact: A study of bias in recidivism prediction instrumentscited by 671
- 2017On Fairness and Calibrationcited by 406
- 2022An Extensive Data Processing Pipeline for MIMIC-IVcited by 39
- 2023On Fairness of Medical Image Classification with Multiple Sensitive Attributes via Learning Orthogonal Representationscited by 17
- 2023Last-Layer Fairness Fine-tuning is Simple and Effective for Neural Networkscited by 17
- 2021MIMIC-IF: Interpretability and Fairness Evaluation of Deep Learning Models on MIMIC-IV Datasetcited by 15
- 2023M3Fair: Mitigating Bias in Healthcare Data through Multi-Level and Multi-Sensitive-Attribute Reweighting Methodcited by 4
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