DischargeBench: Pre-Deployment Evaluation of LLM Discharge Educators through Persona-Grounded Patient Simulation
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Abstract (arXiv)
Effective discharge education is personalized: a clinician adapts the discharge plan to each patient's literacy, recall, and personality. Before large language models (LLMs) take on this role with real patients, they need to be evaluated in conversations with diverse patients, yet existing evaluations target static, artifact-generation, or question-answering tasks. We introduce **DischargeBench**, a pre-deployment benchmark in which a candidate LLM educator teaches a persona-grounded simulated patient in an open-ended, multi-turn conversation. We curate **MIMIC-IV-Ext-DischargeBench**, 320 cases across 16 ICD chapters, each paired with a patient persona that varies personality, education level, health literacy, and recall. Each conversation is scored on Conversation Quality, Topic Checklist Score (TCS), Simulated Comprehension Score (SCS), and a Claim-Level Safety Audit (CLSA) by an LLM judge validated against physician annotations. Across eight closed- and open-source LLMs, the best model scored only 0.70 on TCS and 0.72 on SCS, and distrustful and anxious patients lowered comprehension for every model. DischargeBench is intended as a screening step before human evaluation, not as evidence of readiness to educate patients.
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12 of 68 references.
References · 12
- 2019Sentence-BERT: Sentence Embeddings using Siamese BERT-Networkscited by 9,170
- 2023AutoGen: Enabling Next-Gen LLM Applications via Multi-Agent Conversationcited by 1,988
- 2021QuestEval: Summarization Asks for Fact-based Evaluationcited by 244
- 2024AgentClinic: a multimodal agent benchmark to evaluate AI in simulated clinical environmentscited by 231
- 2024Roleplay-doh: Enabling Domain-Experts to Create LLM-simulated Patients via Eliciting and Adhering to Principlescited by 73
- 2024EHRNoteQA: An LLM Benchmark for Real-World Clinical Practice Using Discharge Summariescited by 35
- 2025LLMEval-Med: A Real-world Clinical Benchmark for Medical LLMs with Physician Validationcited by 34
- 2025PatientSim: A Persona-Driven Simulator for Realistic Doctor-Patient Interactionscited by 32
- 2025Advancing Conversational Diagnostic AI with Multimodal Reasoningcited by 20
- 2025DischargeSim: A Simulation Benchmark for Educational Doctor-Patient Communication at Dischargecited by 7
- 2025ChatThero: An LLM-Supported Chatbot for Behavior Change and Therapeutic Support in Addiction Recoverycited by 4
- 2025Chatbot To Help Patients Understand Their Healthcited by 4
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