mlsanityData to 7 Oct 2026

Beyond Information Seeking: Severity-Aware Question Supervision for Proactive Medical Dialogue

arXiv 2608.24521 ↗First posted 25 Aug 2026cs.CLcited by 0

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Abstract (arXiv)

Proactive medical dialogue requires an agent to decide what to ask from incomplete patient information. Existing information-seeking approaches commonly prioritize questions that most reduce diagnostic uncertainty, but this criterion overlooks an important property of medical diagnosis: different diagnostic errors can carry substantially different consequences. The most informative question may therefore differ from the one most valuable for the downstream decision. We propose Expected-Severity-Risk (ESR), a consequence-aware question-supervision objective that values each candidate by its expected reduction in severity-aware terminal risk. Because questions must be selected before their answers are observed, ESR marginalizes over possible answers using train-only population statistics. Its rankings are then distilled into a prefix-only language policy, requiring no teacher-side risk computation at deployment. Across three matched Qwen3-4B training seeds on DDxPlus, ESR reduces mean high-severity diagnostic miss from 0.0645 to 0.0455 (29.5% relative reduction) and improves mean diagnostic accuracy from 0.9123 to 0.9320 while requiring only 0.14 additional questions per dialogue. Fixed-budget analyses show that the distinction persists when question count is controlled, while a matched expected-0/1-risk student control further isolates the contribution of asymmetric severity weighting. These results support moving proactive medical dialogue beyond uncertainty reduction toward consequence-aware evidence acquisition.

Key facts. No citing papers in the map yet (data through 7 Oct 2026). Builds on 14 of its 24 references that are in the map. First posted on arXiv 25 Aug 2026.

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14 of 24 references.

References · 14

  1. 2021LoRA: Low-Rank Adaptation of Large Language Modelscited by 14,084
  2. 2025Qwen3 Technical Reportcited by 8,195
  3. 2017On Calibration of Modern Neural Networkscited by 4,860
  4. 2022DDXPlus: A New Dataset For Automatic Medical Diagnosiscited by 87
  5. 2018EDDI: Efficient Dynamic Discovery of High-Value Information with Partial VAEcited by 85
  6. 2019End-to-End Knowledge-Routed Relational Dialogue System for Automatic Diagnosiscited by 70
  7. 2020Active Feature Acquisition with Generative Surrogate Modelscited by 53
  8. 2025Qwen Look Again: Guiding Vision-Language Reasoning Models to Re-attention Visual Informationcited by 27
  9. 2025ProMed: Shapley Information Gain Guided Reinforcement Learning for Proactive Medical LLMscited by 12
  10. 2025Doctor-R1: Mastering Clinical Inquiry with Experiential Agentic Reinforcement Learningcited by 11
  11. 2026ATPO: Adaptive Tree Policy Optimization for Multi-Turn Medical Dialoguecited by 8
  12. 2021Knowledge Grounded Conversational Symptom Detection with Graph Memory Networkscited by 6
2 more
  1. 2026Residual Decoding: Mitigating Hallucinations in Large Vision-Language Models via History-Aware Residual Guidancecited by 5
  2. 2026MedClarify: An information-seeking AI agent for medical diagnosis with case-specific follow-up questionscited by 3

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