Beyond Information Seeking: Severity-Aware Question Supervision for Proactive Medical Dialogue
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Abstract (arXiv)
Proactive medical dialogue requires an agent to decide what to ask from incomplete patient information. Existing information-seeking approaches commonly prioritize questions that most reduce diagnostic uncertainty, but this criterion overlooks an important property of medical diagnosis: different diagnostic errors can carry substantially different consequences. The most informative question may therefore differ from the one most valuable for the downstream decision. We propose Expected-Severity-Risk (ESR), a consequence-aware question-supervision objective that values each candidate by its expected reduction in severity-aware terminal risk. Because questions must be selected before their answers are observed, ESR marginalizes over possible answers using train-only population statistics. Its rankings are then distilled into a prefix-only language policy, requiring no teacher-side risk computation at deployment. Across three matched Qwen3-4B training seeds on DDxPlus, ESR reduces mean high-severity diagnostic miss from 0.0645 to 0.0455 (29.5% relative reduction) and improves mean diagnostic accuracy from 0.9123 to 0.9320 while requiring only 0.14 additional questions per dialogue. Fixed-budget analyses show that the distinction persists when question count is controlled, while a matched expected-0/1-risk student control further isolates the contribution of asymmetric severity weighting. These results support moving proactive medical dialogue beyond uncertainty reduction toward consequence-aware evidence acquisition.
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References · 14
- 2021LoRA: Low-Rank Adaptation of Large Language Modelscited by 14,084
- 2025Qwen3 Technical Reportcited by 8,195
- 2017On Calibration of Modern Neural Networkscited by 4,860
- 2022DDXPlus: A New Dataset For Automatic Medical Diagnosiscited by 87
- 2018EDDI: Efficient Dynamic Discovery of High-Value Information with Partial VAEcited by 85
- 2019End-to-End Knowledge-Routed Relational Dialogue System for Automatic Diagnosiscited by 70
- 2020Active Feature Acquisition with Generative Surrogate Modelscited by 53
- 2025Qwen Look Again: Guiding Vision-Language Reasoning Models to Re-attention Visual Informationcited by 27
- 2025ProMed: Shapley Information Gain Guided Reinforcement Learning for Proactive Medical LLMscited by 12
- 2025Doctor-R1: Mastering Clinical Inquiry with Experiential Agentic Reinforcement Learningcited by 11
- 2026ATPO: Adaptive Tree Policy Optimization for Multi-Turn Medical Dialoguecited by 8
- 2021Knowledge Grounded Conversational Symptom Detection with Graph Memory Networkscited by 6
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