Lethe: How Hard Is It to Forget? A Benchmark for Federated Unlearning in Medical Imaging
On the map: LLM safety and security → Machine unlearning
Abstract (arXiv)
Federated learning enables medical-imaging models to be trained across hospitals, and privacy law, most explicitly the GDPR ``right to be forgotten'', turns removing a hospital's, a class's, or a patient's influence from such a model into a federated unlearning problem. This need is most acute in medicine, where patients withdraw consent and hospitals leave collaborations. Yet nearly all unlearning evidence comes from natural images, whose heterogeneity and task structure differ sharply from clinical data, so it is unclear whether existing methods transfer, and no shared protocol covers clinical data. We present Lethe, a benchmark for federated unlearning in medical imaging. It evaluates twelve methods across eight task families, from classification and segmentation to denoising, cross-modality synthesis, and vision-language question answering, at three forgetting granularities and against a retrained gold standard on utility, privacy, and cost. The central result is that what separates methods is the difficulty of the forgetting request, not the method itself. The easy removals that dominate the literature leave the methods that preserve utility indistinguishable, while only hard ones separate them. More striking, on the many medical tasks that generalize across sites, forgetting a client barely changes task performance, leaving residual membership as the signal that must be erased.
Key facts. No citing papers in the map yet (data through 14 Oct 2026). Placed in Machine unlearning, one of 12 directions in LLM safety and security. Builds on 31 of its 50 references that are in the map. First posted on arXiv 2 Aug 2026.
Builds on
31 of 50 references.
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Same direction, newest first
- 2024Deep Unlearn: Benchmarking Machine Unlearning for Image Classification2 Oct
- 2024Inexact Unlearning Needs More Careful Evaluations to Avoid a False Sense of Privacy2 Mar
Other references · 29
- 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,713
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- 2020WILDS: A Benchmark of in-the-Wild Distribution Shiftscited by 1,375
- 2021Membership Inference Attacks From First Principlescited by 878
- 2019Measuring the Effects of Non-Identical Data Distribution for Federated Visual Classificationcited by 851
- 2021MedMNIST v2 -- A large-scale lightweight benchmark for 2D and 3D biomedical image classificationcited by 690
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17 more
- 2021SLAKE: A Semantically-Labeled Knowledge-Enhanced Dataset for Medical Visual Question Answeringcited by 449
- 2022FLamby: Datasets and Benchmarks for Cross-Silo Federated Learning in Realistic Healthcare Settingscited by 125
- 2021Federated Unlearning via Class-Discriminative Pruningcited by 115
- 2022Federated Unlearning: How to Efficiently Erase a Client in FL?cited by 95
- 2023Prompt Federated Learning for Weather Forecasting: Toward Foundation Models on Meteorological Datacited by 40
- 2024Federated Unlearning: A Survey on Methods, Design Guidelines, and Evaluation Metricscited by 27
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- 2025NoT: Federated Unlearning via Weight Negationcited by 15
- 2024Federated Foundation Models on Heterogeneous Time Seriescited by 13
- 2025FeDaL: Federated Dataset Learning for General Time Series Foundation Modelscited by 10
- 2024Enable the Right to be Forgotten with Federated Client Unlearning in Medical Imagingcited by 9
- 2022Interpretable CNN-Multilevel Attention Transformer for Rapid Recognition of Pneumonia from Chest X-Ray Imagescited by 8
- 2024FedQUIT: On-Device Federated Unlearning via a Quasi-Competent Virtual Teachercited by 2
- 2026FedCARE: Federated Unlearning with Conflict-Aware Projection and Relearning-Resistant Recoverycited by 2
- 2025Federated Unlearning Made Practical: Seamless Integration via Negated Pseudo-Gradientscited by 1
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