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Explaining BiomedCLIP with Weighted Banzhaf Interactions Supported by Tree-Gram Parsing

arXiv 2607.23368 ↗First posted 25 Jul 2026cs.CV cs.AI cs.CLcited by 0

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Abstract (arXiv)

Vision-Language Models (VLMs) are demonstrating significant capabilities in medical tasks like radiology analysis, yet providing faithful and interpretable explanations remains a key consideration for their responsible deployment in clinical settings. However, existing explanation methods, such as the widely used FIxLIP framework, often struggle with the fine-grained nature of modern tokenizers. The tokenization problem fragments clinical concepts---splitting terms like "saddle embolus" into scattered, meaningless subwords---which leads to noisy, semantically incoherent cross-modal attributions. Such fragmentation also results in a combinatorial explosion of interaction possibilities, obscuring the model's true reasoning. To address this, we introduce ParseFIxLIP, an extension that incorporates the Tree-Gram Parsing into the Banzhaf interaction game used by FIxLIP. This semantically informed strategy utilizes dependency parsing trees to define explanation players by grouping related text tokens into semantically coherent units. Our smart_depth grouping strategy, merging tokens according to spaCy token dependency tree, successfully mitigates concept fragmentation, yielding substantially more interpretable cross-modal interactions by unifying complex medical concepts. Quantitatively, while baselines struggled with the high dimensionality of long captions, our parsing approach maintained statistical robustness and semantic parsimony. Qualitative analysis on BiomedCLIP, validated on medical imagery (ROCOv2) and general examples, confirms that the approach accurately captures the synergistic influence of grouped words on model predictions. In conclusion, our work offers intuitive and clinically relevant insights into VLM decision-making, fulfilling the critical need for coherent explanations in the medical domain.

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References · 15

  1. 2021Learning Transferable Visual Models From Natural Language Supervisioncited by 33,456
  2. 2022BLIP: Bootstrapping Language-Image Pre-training for Unified Vision-Language Understanding and Generationcited by 4,310
  3. 2021Scaling Up Visual and Vision-Language Representation Learning With Noisy Text Supervisioncited by 3,848
  4. 2021Generic Attention-model Explainability for Interpreting Bi-Modal and Encoder-Decoder Transformerscited by 316
  5. 2022Post-hoc Concept Bottleneck Modelscited by 289
  6. 2020Explaining by Removing: A Unified Framework for Model Explanationcited by 218
  7. 2020Byte Pair Encoding is Suboptimal for Language Model Pretrainingcited by 189
  8. 2020Improving KernelSHAP: Practical Shapley Value Estimation via Linear Regressioncited by 153
  9. 2022CLIP-Dissect: Automatic Description of Neuron Representations in Deep Vision Networkscited by 144
  10. 2021Between words and characters: A Brief History of Open-Vocabulary Modeling and Tokenization in NLPcited by 130
  11. 2022From Shapley Values to Generalized Additive Models and backcited by 59
  12. 2024ROCOv2: Radiology Objects in COntext Version 2, an Updated Multimodal Image Datasetcited by 54
3 more
  1. 2023SHAP-IQ: Unified Approximation of any-order Shapley Interactionscited by 50
  2. 2022A k-additive Choquet integral-based approach to approximate the SHAP values for local interpretability in machine learningcited by 8
  3. 2025Explaining Similarity in Vision-Language Encoders with Weighted Banzhaf Interactionscited by 6

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  1. 2025An Explainable Biomedical Foundation Model via Large-Scale Concept-Enhanced Vision-Language Pre-training
  2. 2025MedXplain-VQA: Multi-Component Explainable Medical Visual Question Answering
  3. 2024Envisioning MedCLIP: A Deep Dive into Explainability for Medical Vision-Language Models
  4. 2025From Compound Figures to Composite Understanding: Developing a Multi-Modal LLM from Biomedical Literature with Medical Multiple-Image Benchmarking and Validation
  5. 2025BiomedXPro: Prompt Optimization for Explainable Diagnosis with Biomedical Vision Language Models
  6. 2026KANEx: Translating Kolmogorov-Arnold Networks' Interpretability to Medical Explainability
  7. 2025MedAtlas: Evaluating LLMs for Multi-Round, Multi-Task Medical Reasoning Across Diverse Imaging Modalities and Clinical Text
  8. 2024MedViLaM: A multimodal large language model with advanced generalizability and explainability for medical data understanding and generation